Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Amy L Moore"'
Autor:
Ikenna G Madu, Megan Files, Dima N Gharaibeh, Amy L Moore, Kie-Hoon Jung, Brian B Gowen, Dongcheng Dai, Kevin F Jones, Shanthakumar R Tyavanagimatt, James R Burgeson, Marcus J Korth, Kristin M Bedard, Shawn P Iadonato, Sean M Amberg
Publikováno v:
PLoS Pathogens, Vol 14, Iss 12, p e1007439 (2018)
Arenaviruses are a significant cause of hemorrhagic fever, an often-fatal disease for which there is no approved antiviral therapy. Lassa fever in particular generates high morbidity and mortality in West Africa, where the disease is endemic, and a r
Externí odkaz:
https://doaj.org/article/158943d5f7714c32981e426acdf08c68
Autor:
Amy L. Moore, Lee Hasselbacher, Crystal P. Tyler, Anthony E. Rodriguez-Ortiz, Melissa Gilliam
Publikováno v:
Women's health issues : official publication of the Jacobs Institute of Women's Health.
Legislation allows adolescents to access comprehensive contraceptive care; however, provider practices remain unclear. We examined predictors of provider knowledge and comfort surrounding the provision of contraceptive care to adolescents.We mailed a
Publikováno v:
Archives of sexual behavior. 50(5)
The purported goals of commercial sex work criminalization policies in the United States have shifted over the past two decades as local jurisdictions have adopted End Demand reforms. These reforms aim to refocus arrest from individuals who sell sexu
Autor:
James R. Burgeson, Kristin Bedard, Sean M. Amberg, Megan Files, Kevin F. Jones, Shawn P. Iadonato, Marcus J. Korth, Dima N. Gharaibeh, Dongcheng Dai, Amy L. Moore, Ikenna G. Madu, Shanthakumar R. Tyavanagimatt, Kieh-Hoon Jung, Brian B. Gowen
Publikováno v:
PLoS Pathogens, Vol 14, Iss 12, p e1007439 (2018)
PLoS Pathogens
Animal, Dairy, and Veterinary Science Faculty Publications
PLoS Pathogens
Animal, Dairy, and Veterinary Science Faculty Publications
Arenaviruses are a significant cause of hemorrhagic fever, an often-fatal disease for which there is no approved antiviral therapy. Lassa fever in particular generates high morbidity and mortality in West Africa, where the disease is endemic, and a r
Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole
Autor:
Natasha R. Cerruti, James R. Burgeson, Sean M. Amberg, Ryan A. Larson, Dongcheng Dai, Dima N. Gharaibeh, Dennis E. Hruby, Amy L. Moore, Tove' C. Bolken
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:744-749
A chemically diverse library of about 400,000 small molecules was screened for antiviral activity against lentiviral pseudotypes with the Lassa virus envelope glycoprotein (LASV GP) gene incorporated. High-throughput screening resulted in discovery o
Autor:
James R. Burgeson, Amy L. Moore, Dima N. Gharaibeh, Dongcheng Dai, Natasha R. Cerruti, Ryan A. Larson, Dennis E. Hruby, Sean M. Amberg
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:750-756
A series of potent arenavirus inhibitors sharing a benzimidazole core were previously reported by our group. SAR studies were expanded beyond the previous analysis, which involved the attached phenyl rings and methylamino linker portion, to include m
Autor:
Stacy Cooper, Bailey, Michael K, Paasche-Orlow, William G, Adams, Samantha A, Brokenshire, Laura A, Hedlund, Ryan P, Hickson, Christine U, Oramasionwu, Amy L, Moore, Danielle M, McCarthy, Laura M, Curtis, Mary J, Kwasny, Michael S, Wolf
Publikováno v:
Contemporary clinical trials. 51
Background Adverse drug events (ADEs) affect millions of patients annually and place a significant burden on the healthcare system. The Food and Drug Administration (FDA) has developed patient safety information for high-risk medications that pose se
Autor:
Seth M. Daly, Erin K. Sully, David E. Greenberg, Christina M. Moody, Lixin Li, Michael Wong, Stacey M. Bailey, Amy L. Moore, Carolyn R. Sturge, Patrice Nordmann, Bruce L. Geller
Publikováno v:
The Journal of antimicrobial chemotherapy. 72(3)
Objectives The objective of this study was to test the efficacy of an inhibitor of the New Delhi metallo-β- lactamase (NDM-1). Inhibiting expression of this type of antibiotic-resistance gene has the potential to restore antibiotic susceptibility in
Autor:
Ryan A. Larson, Amy L. Moore, Sean M. Amberg, Dongcheng Dai, Dima N. Gharaibeh, Tove' C. Bolken, Dennis E. Hruby, James R. Burgeson
Previously we reported the optimization of antiviral scaffolds containing benzimidazole and related heterocycles possessing activity against a variety of arenaviruses. These series of compounds were discovered through an HTS campaign of a 400,000 sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc42c9ccfffc560a7c2e1a9e9ef4cbc
https://europepmc.org/articles/PMC3836667/
https://europepmc.org/articles/PMC3836667/
Autor:
J. John Mann, Matthew F. Muldoon, James M. Perel, Amy L. Moore, Stephen B. Manuck, Cathy L. Jansma
Publikováno v:
Biological Psychiatry. 39:761-768
The plasma prolactin response to a single-dose fenfluramine challenge is increasingly utilized in psychiatric research as an indirect and noninvasive measure of central serotonergic activity. However, the influences of age, gender, and body weight on