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AB569, a non-toxic combination of acidified nitrite and EDTA, is effective at killing the notorious Iraq/Afghanistan combat wound pathogens, multi-drug resistant Acinetobacter baumannii and Acinetobacter spp.

Autor: Amy L Bogue, Warunya Panmanee, Cameron T McDaniel, Joel E Mortensen, Edwin Kamau, Luis A Actis, Jay A Johannigman, Michael J Schurr, Latha Satish, Nalinikanth Kotagiri, Daniel J Hassett

Publikováno v: PLoS ONE, Vol 16, Iss 3, p e0247513 (2021)

Multi-drug resistant (MDR) Acinetobacter baumannii (Ab) and Acinetobacter spp. present monumental global health challenges. These organisms represent model Gram-negative pathogens with known antibiotic resistance and biofilm-forming properties. Herei

Externí odkaz: https://doaj.org/article/5f51ec5a25dc45d88d8165127110bad1

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Autor: Joel E. Mortensen, Latha Satish, Daniel J. Hassett, Luis A. Actis, Jay A. Johannigman, Michael J. Schurr, Cameron T. McDaniel, Edwin Kamau, Warunya Panmanee, Amy L. Bogue, Nalinikanth Kotagiri

Publikováno v: PLoS ONE, Vol 16, Iss 3, p e0247513 (2021)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddaccc9e28fba233b003ca8a68edb85
https://doaj.org/article/5f51ec5a25dc45d88d8165127110bad1

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AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria

Publikováno v: Proc Natl Acad Sci U S A

Antibiotic-resistant superbug bacteria represent a global health problem with no imminent solutions. Here we demonstrate that the combination (termed AB569) of acidified nitrite (A-NO 2 − ) and Na 2 -EDTA (disodium ethylenediaminetetraacetic acid)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdca1dcb1fd20e5c416cb0d0091e09f3
https://pubmed.ncbi.nlm.nih.gov/32071223

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