Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Amy L, Hazen"'
Autor:
Janelle M. Korf, Pedram Honarpisheh, Eric C. Mohan, Anik Banerjee, Maria P. Blasco-Conesa, Parisa Honarpisheh, Gary U. Guzman, Romeesa Khan, Bhanu P. Ganesh, Amy L. Hazen, Juneyoung Lee, Aditya Kumar, Louise D. McCullough, Anjali Chauhan
Publikováno v:
The Journal of Immunology. 209:288-300
Recent studies have highlighted the deleterious contributions of B cells to post-stroke recovery and cognitive decline. Different B cell subsets have been proposed on the basis of expression levels of transcription factors (e.g., T-bet) as well as sp
Autor:
William W. Won, Frank Blixt, Pedram Honarpisheh, Bhanu P. Ganesh, J. Weldon Furr, Robert M. Bryan, Jacob Hudobenko, Louise D. McCullough, Alexis S. Mobley, Katherine E. Brannick, M.S.D.V.M. Liang Zhu, Yashasvee Munshi, Amy L. Hazen, Maria P. Blasco Conesa, M.S. Juneyoung Lee, John d'Aigle
Publikováno v:
Brain Behav Immun
Aging is associated with dysfunction of the gut microbiota-immune-brain axis, a major regulatory axis in both brain health and in central nervous system (CNS) diseases. Antigen presenting cells (APCs) play a major role in sensing changes in the gut m
Autor:
Janelle M, Korf, Pedram, Honarpisheh, Eric C, Mohan, Anik, Banerjee, Maria P, Blasco-Conesa, Parisa, Honarpisheh, Gary U, Guzman, Romeesa, Khan, Bhanu P, Ganesh, Amy L, Hazen, Juneyoung, Lee, Aditya, Kumar, Louise D, McCullough, Anjali, Chauhan
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(2)
Recent studies have highlighted the deleterious contributions of B cells to post-stroke recovery and cognitive decline. Different B cell subsets have been proposed on the basis of expression levels of transcription factors (e.g., T-bet) as well as sp
Autor:
William W. Won, John d'Aigle, Frank Blixt, Juneyoung Lee, Darius F. Miranda-Sohrabji, Alexis S. Mobley, Robert M. Bryan, Amy L. Hazen, Maria P. Blasco Conesa, Jesus Bautista Garrido, Pedram Honarpisheh, Anjali Chauhan, Bhanu P. Ganesh, Louise D. McCullough
Publikováno v:
Stroke. 51
Aging is a non-modifiable risk factor for stroke. Aging is accompanied by chronic low-grade inflammation and gut dysbiosis (a pathological imbalance of microbial organisms in the gut). Age-related gut dysbiosis exacerbates stroke outcomes and can be
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical CytologyLiterature Cited. 97(2)
The rapid advancement of immunotherapy strategies has created a need for technologies that can reliably and reproducibly identify rare populations, detect subtle changes in modulatory signals, and assess antigenic expression patterns that are time-se
Publikováno v:
Methods (San Diego, Calif.).
With the release and use of the Becton Dickenson FACS Diva Software, the use of Area as the default parameter came into play. As such, the use of area as a calculated parameter, methods were needed to be employed to ensure doublet discrimination and
Publikováno v:
European Journal of Immunology. 42:1785-1795
We previously showed that germline or induced SHIP deficiency expands immunoregulatory cell numbers in T lymphoid and myeloid lineages. We postulated these increases could be interrelated. Here, we show that myeloid-specific ablation of SHIP leads to
Autor:
Holly Robinson, Melissa B. Aldrich, Mary A. Hall, Eva M. Sevick-Muraca, David L. Haviland, Amy L. Hazen, Pier Anne Lachance, Ali Azhdarinia
Publikováno v:
Contrast Media & Molecular Imaging. 7:338-345
Prior to imaging agent use in preclinical studies and clinical diagnostics, biological activity must be validated. The Lindmo assay has been used conventionally to quantify radiolabeled antibody (Ab) immunoreactivity, although published findings sugg
Autor:
M. James You, James G. Jackson, Tiffany M. Sills, Hussein A. Abbas, Karen K. Hirschi, Süleyman Coşkun, Guillermina Lozano, Amy L. Hazen, Daniela R. Maccio
Publikováno v:
Cell Stem Cell. 7(5):606-617
Mdm2 is an E3 ubiquitin ligase that targets p53 for degradation. p53(515C) (encoding p53R172P) is a hypomorphic allele of p53 that rescues the embryonic lethality of Mdm2(-/-) mice. Mdm2(-/-) p53(515C/515C) mice, however, die by postnatal day 13 resu
Autor:
Amy L. Hazen, Oliver Winter, Caroline Desponts, Michelle J. Smith, Katrin Moser, William G. Kerr
Publikováno v:
Blood. 113:2924-2933
SH2-domain-containing inositol 5′-phosphatase-1 (SHIP) deficiency significantly increases the number of hematopoietic stem cells (HSCs) present in the bone marrow (BM). However, the reconstitution capacity of these HSCs is severely impaired, sugges