Zobrazeno 1 - 10 of 54 pro vyhledávání: '"Amy Ku"'
1
Akademický článek
Soluble antigen arrays provide increased efficacy and safety over free peptides for tolerogenic immunotherapy
Autor: Rebuma Firdessa-Fite, Stephanie N. Johnson, Camillo Bechi Genzano, Martin A. Leon, Amy Ku, Fernando A. Ocampo Gonzalez, Joshua D. Milner, Joshua O. Sestak, Cory Berkland, Remi J. Creusot
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
Autoantigen-specific immunotherapy using peptides offers a more targeted approach to treat autoimmune diseases, but clinical implementation has been challenging. We previously showed that multivalent delivery of peptides as soluble antigen arrays (SA
Externí odkaz: https://doaj.org/article/49beca032d1f4ac2a42d36f7cf922cc6
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3
Data from Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer
Autor: Yi Li, Yi-Chieh Nancy Du, Susan G. Hilsenbeck, Lan Qin, Sagar Dhamne, Jyoti Kapali, Amy Ku, Weiyu Jiang, Wen Bu, Adelaide Young
Current chemopreventive strategies require 3–5 years of continuous treatment and have the concerns of significant side effects; therefore, new chemopreventive agents that require shorter and safer treatments are urgently needed. In this study, we d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ac7f72c07e07b3392ebc5a75ecefbcf
https://doi.org/10.1158/1940-6207.c.6547696.v1
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4
Akademický článek
Predicting disability and mortality in CV2/CRMP5‐IgG associated paraneoplastic neurologic disorders
Autor: Sanem P. Uysal, Yadi Li, Nicolas R. Thompson, Alex Milinovich, Justin R. Abbatemarco, Jeffrey A. Cohen, Devon S. Conway, Daniel Ontaneda, John A. Morren, Amy Kunchok
Publikováno v: Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 710-718 (2024)
Abstract Background We aimed to investigate the prognostic factors associated with clinical outcomes in CV2/Collapsin response‐mediator protein 5 (CRMP5)‐IgG paraneoplastic neurologic disorders (PND). Methods This is a retrospective study of pati
Externí odkaz: https://doaj.org/article/0c5436a9057f40379fe0b91e5f65da87
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5
Akademický článek
The Transition From Homogeneous to Heterogeneous Machine Learning in Neuropsychiatric Research
Autor: Qingyu Zhao, Kate B. Nooner, Susan F. Tapert, Ehsan Adeli, Kilian M. Pohl, Amy Kuceyeski, Mert R. Sabuncu
Publikováno v: Biological Psychiatry Global Open Science, Vol 5, Iss 1, Pp 100397- (2025)
Despite the advantage of neuroimaging-based machine learning (ML) models as pivotal tools for investigating brain-behavior relationships in neuropsychiatric studies, these data-driven predictive approaches have yet to yield substantial, clinically ac
Externí odkaz: https://doaj.org/article/85c8ecc45480465c9a62140f0b717cc2
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7
Akademický článek
Infarct‐related structural disconnection and delirium in surgical aortic valve replacement patients
Autor: Jeffrey N. Browndyke, Lewis E. Tomalin, Guray Erus, Jessica R. Overbey, Amy Kuceyeski, Alan J. Moskowitz, Emilia Bagiella, Alexander Iribarne, Michael Acker, Michael Mack, Joseph Mathew, Patrick O'Gara, Annetine C. Gelijns, Mayte Suarez‐Farinas, Steven R. Messé, for the Cardiothoracic Surgical Trials Network (CTSN) Investigators
Publikováno v: Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 263-277 (2024)
Abstract Objective Although acute brain infarcts are common after surgical aortic valve replacement (SAVR), they are often unassociated with clinical stroke symptoms. The relationship between clinically “silent” infarcts and in‐hospital deliriu
Externí odkaz: https://doaj.org/article/0ca0493bd977494bb21b2eaec3c71f1c
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8
Akademický článek
Inebilizumab reduces neuromyelitis optica spectrum disorder risk independent of FCGR3A polymorphism
Autor: Ho Jin Kim, Orhan Aktas, Kristina R. Patterson, Schaun Korff, Amy Kunchok, Jeffrey L. Bennett, Brian G. Weinshenker, Friedemann Paul, Hans‐Peter Hartung, Daniel Cimbora, Michael A. Smith, Nanette Mittereder, William A. Rees, Dewei She, Bruce A. C. Cree
Publikováno v: Annals of Clinical and Translational Neurology, Vol 10, Iss 12, Pp 2413-2420 (2023)
Abstract Inebilizumab, a humanized, glycoengineered, IgG1 monoclonal antibody that depletes CD19+ B‐cells, is approved to treat aquaporin 4 (AQP4) IgG‐seropositive neuromyelitis optica spectrum disorder (NMOSD). Inebilizumab is afucosylated and e
Externí odkaz: https://doaj.org/article/117e79e5e7134a03b6b3f3c65a13a5f5
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