Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Amy Kempf"'
Autor:
Xinyu Ning, Darshita Budhadev, Sara Pollastri, Inga Nehlmeier, Amy Kempf, Iain Manfield, W. Bruce Turnbull, Stefan Pöhlmann, Anna Bernardi, Xin Li, Yuan Guo, Dejian Zhou
Publikováno v:
JACS Au, Vol 4, Iss 8, Pp 3295-3309 (2024)
Externí odkaz:
https://doaj.org/article/757f82838ccf4e62a5f84306bc3cb42c
Autor:
Markus Hoffmann, Lok-Yin Roy Wong, Prerna Arora, Lu Zhang, Cheila Rocha, Abby Odle, Inga Nehlmeier, Amy Kempf, Anja Richter, Nico Joel Halwe, Jacob Schön, Lorenz Ulrich, Donata Hoffmann, Martin Beer, Christian Drosten, Stanley Perlman, Stefan Pöhlmann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The SARS-CoV-2 Omicron subvariants BA.1 and BA.2 exhibit reduced lung cell infection relative to previously circulating SARS-CoV-2 variants, which may account for their reduced pathogenicity. However, it is unclear whether lung cell infectio
Externí odkaz:
https://doaj.org/article/d5890df25e6a47a4a0fb537c6e7a81a4
Autor:
Lu Zhang, Alexandra Dopfer-Jablonka, Inga Nehlmeier, Amy Kempf, Luise Graichen, Noemí Calderón Hampel, Anne Cossmann, Metodi V. Stankov, Gema Morillas Ramos, Sebastian R. Schulz, Hans-Martin Jäck, Georg M. N. Behrens, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
Vaccines, Vol 12, Iss 5, p 487 (2024)
Transmissibility and immune evasion of the recently emerged, highly mutated SARS-CoV-2 BA.2.87.1 are unknown. Here, we report that BA.2.87.1 efficiently enters human cells but is more sensitive to antibody-mediated neutralization than the currently d
Externí odkaz:
https://doaj.org/article/cd69a4083c014053bc288930db5d3c65
Autor:
Markus Hoffmann, Anzhalika Sidarovich, Prerna Arora, Nadine Krüger, Inga Nehlmeier, Amy Kempf, Luise Graichen, Martin S. Winkler, Daniela Niemeyer, Christine Goffinet, Christian Drosten, Sebastian Schulz, Hans-Martin Jäck, Stefan Pöhlmann
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT SARS-CoV-2 variants of concern (VOC) acquired mutations in the spike (S) protein, including E484K, that confer resistance to neutralizing antibodies. However, it is incompletely understood how these mutations impact viral entry into host cel
Externí odkaz:
https://doaj.org/article/b456191be4ea4ac29d1a309a4697f9af
Autor:
Prerna Arora, Amy Kempf, Inga Nehlmeier, Luise Graichen, Martin S. Winkler, Martin Lier, Sebastian Schulz, Hans-Martin Jäck, Anne Cossmann, Metodi V. Stankov, Georg M.N. Behrens, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110754- (2022)
Summary: Rapid spread of SARS-CoV-2 variants C.1.2 and B.1.621 (Mu variant) in Africa and the Americas, respectively, as well as a high number of mutations in the viral spike proteins raised concerns that these variants might pose an elevated threat
Externí odkaz:
https://doaj.org/article/1fb852d0d9bb437db843675916e4b705
Autor:
Prerna Arora, Lu Zhang, Cheila Rocha, Luise Graichen, Inga Nehlmeier, Amy Kempf, Anne Cossmann, Gema Morillas Ramos, Eva Baier, Björn Tampe, Onnen Moerer, Steffen Dickel, Martin S. Winkler, Georg M. N. Behrens, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14057 (2022)
Recently, a recombinant SARS-CoV-2 lineage, XD, emerged that harbors a spike gene that is largely derived from the Omicron variant BA.1 in the genetic background of the Delta variant. This finding raised concerns that the recombinant virus might exhi
Externí odkaz:
https://doaj.org/article/14c4ce1145744cba81384e99b38a7b6f
Autor:
Anzhalika Sidarovich, Nadine Krüger, Cheila Rocha, Luise Graichen, Amy Kempf, Inga Nehlmeier, Martin Lier, Anne Cossmann, Metodi V. Stankov, Sebastian R. Schulz, Georg M. N. Behrens, Hans-Martin Jäck, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
Viruses, Vol 14, Iss 11, p 2475 (2022)
The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) facilitates viral entry into host cells and is the key target for neutralizing antibodies. The SARS-CoV-2 lineage B.1.620 carries fifteen mutations in the S protein
Externí odkaz:
https://doaj.org/article/5777d3dcf3384ed790818719c997e62a
Autor:
Markus Hoffmann, Lu Zhang, Nadine Krüger, Luise Graichen, Hannah Kleine-Weber, Heike Hofmann-Winkler, Amy Kempf, Stefan Nessler, Joachim Riggert, Martin Sebastian Winkler, Sebastian Schulz, Hans-Martin Jäck, Stefan Pöhlmann
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109017- (2021)
Summary: Transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from humans to farmed mink has been observed in Europe and the US. In the infected animals, viral variants arose that harbored mutations in the spike (S) protein, t
Externí odkaz:
https://doaj.org/article/cf114b85f78c491d9f80733acf2b0401
Autor:
Markus Hoffmann, Prerna Arora, Inga Nehlmeier, Amy Kempf, Anne Cossmann, Sebastian R. Schulz, Gema Morillas Ramos, Luis A. Manthey, Hans-Martin Jäck, Georg M. N. Behrens, Stefan Pöhlmann
Publikováno v:
Cellular & Molecular Immunology. 20:419-422
Autor:
Inga Nehlmeier, Amy Kempf, Prerna Arora, Anne Cossmann, Alexandra Dopfer-Jablonka, Metodi V. Stankov, Sebastian R. Schulz, Hans-Martin Jäck, Georg M. N. Behrens, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
Cellular & Molecular Immunology.