Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Amy K. Smith"'
Autor:
Cathy A. Larson, Edward A. Roth, Alycia J. Sterenberg Mahon, Michael Crinion, Kelsey Fischer, Sun Hye Yim, Amy K. Smith
Publikováno v:
Journal of Aging and Physical Activity. :1-12
Older adults must have the ability to walk at variable speeds/distances to meet community demands. This single group pre–post test study’s purposes were to examine if actual cadences after 7 weeks of rhythmic auditory stimulation gait training ma
Autor:
Shih-Chao Lin, Brian D Carey, Victoria Callahan, Ji-Hyun Lee, Nicole Bracci, Anurag Patnaik, Amy K Smith, Aarthi Narayanan, Benjamin Lepene, Kylene Kehn-Hall
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227058 (2020)
Nanotrap® (NT) particles are hydrogel microspheres developed for target analyte separation and discovery applications. NT particles consist of cross-linked N-isopropylacrylamide (NIPAm) copolymers that are functionalized with a variety of chemical a
Externí odkaz:
https://doaj.org/article/d51ffe3333f640558d8eb6c338de2a01
Autor:
Angela G. Mkindi, Yolice L. B. Tembo, Ernest R. Mbega, Amy K. Smith, Iain W. Farrell, Patrick A. Ndakidemi, Philip C. Stevenson, Steven R. Belmain
Publikováno v:
Plants, Vol 9, Iss 2, p 149 (2020)
Common bean (Phaseolus vulgaris) is an important food and cash crop in many countries. Bean crop yields in sub-Saharan Africa are on average 50% lower than the global average, which is largely due to severe problems with pests and diseases as well as
Externí odkaz:
https://doaj.org/article/aac4eb7f647f47138d2ae098fe085f78
Publikováno v:
ACS Chemical Neuroscience. 12:3225-3236
Using all-atom explicit solvent replica exchange molecular dynamics simulations, we studied the aggregation of oxidized (ox) Aβ25-35 peptides into dimers mediated by the zwitterionic dimyristoylphosphatidylcholine (DMPC) lipid bilayer. By comparing
Publikováno v:
Journal of Physical Therapy Education. 35:227-236
Publikováno v:
Journal of Chemical Information and Modeling. 59:5207-5217
Using replica exchange with solute tempering all-atom molecular dynamics we studied the equilibrium binding of Abeta25-35 peptide to the ternary bilayer composed of an equimolar mixture of dimyristoylphosphatidylcholine (DMPC), N-palmitoylsphingomyel
Autor:
Amy K. Smith, Dmitri K. Klimov
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
A potential mechanism of cytotoxicity attributed to Alzheimer’s Aβ peptides postulates that their aggregation disrupts membrane structure causing uncontrollable permeation of Ca2+ ions. To gain molecular insights into these processes, we have perf
Publikováno v:
The journal of physical chemistry. B. 125(10)
We used all-atom replica-exchange umbrella sampling molecular dynamics simulations to investigate the partitioning of the charged tetrapeptide KLVF and its neutral apolar counterpart VVIA into the blood-brain barrier (BBB)-mimetic bilayer. Our findin
Publikováno v:
ACS chemical neuroscience. 11(20)
The consequences of phosphorylation of the Aβ25-35 peptide at the position Ser26 on its aggregation have not been examined. To investigate them, we performed all-atom replica exchange simulations probing the binding of phosphorylated Aβ25-35 (pAβ2
Publikováno v:
Journal of chemical information and modeling. 60(8)
Using an all-atom explicit water model and replica exchange umbrella sampling simulations, we investigated the molecular mechanisms of benzoic acid partitioning into two model lipid bilayers. The first was formed of 1,2-dimyristoyl