Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Amy K, Wagner"'
Autor:
Ian G. Gober, Ashley L. Russell, Tyler J. Shick, Vincent A. Vagni, Jenna C. Carlson, Patrick M. Kochanek, Amy K. Wagner
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Uncontrolled neuroinflammation mediates traumatic brain injury (TBI) pathology and impairs recovery. Interleukin-6 (IL-6), a pleiotropic inflammatory regulator, is associated with poor clinical TBI outcomes. IL-6 operates via classical-signa
Externí odkaz:
https://doaj.org/article/203db4b4abdf484d8c8eb4b1304705c9
Autor:
Lauren B, Fisher, Joshua E, Curtiss, Daniel W, Klyce, Paul B, Perrin, Shannon B, Juengst, Kelli W, Gary, Janet P, Niemeier, Flora McConnell, Hammond, Thomas F, Bergquist, Amy K, Wagner, Amanda R, Rabinowitz, Joseph T, Giacino, Ross D, Zafonte
Publikováno v:
American journal of physical medicinerehabilitation.
To predict suicidal ideation one year after moderate to severe traumatic brain injury (TBI).Cross-sectional design with data collected through the prospective, longitudinal TBI Model Systems (TBIMS) network at hospitalization and one year after injur
Autor:
Georgios D. Kitsios, Daniel Kotok, Haopu Yang, Malcolm A. Finkelman, Yonglong Zhang, Noel Britton, Xiaoyun Li, Marina S. Levochkina, Amy K. Wagner, Caitlin Schaefer, John J. Villandre, Rui Guo, John W. Evankovich, William Bain, Faraaz Shah, Yingze Zhang, Barbara A. Methé, Panayiotis V. Benos, Bryan J. McVerry, Alison Morris
Publikováno v:
JCI Insight, Vol 6, Iss 14 (2021)
BACKGROUND The fungal cell wall constituent 1,3-β-d-glucan (BDG) is a pathogen-associated molecular pattern that can stimulate innate immunity. We hypothesized that BDG from colonizing fungi in critically ill patients may translocate into the system
Externí odkaz:
https://doaj.org/article/429f6cee0d194921b825ce997d3304ff
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-19 (2018)
Abstract Background Understanding the interdependencies among inflammatory mediators of tissue damage following traumatic brain injury (TBI) is essential in providing effective, patient-specific care. Activated microglia and elevated concentrations o
Externí odkaz:
https://doaj.org/article/38fe2e1c664e46b59ac9f3d2becb47ea
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 11, Iss , Pp 100185- (2021)
Background: Cognitive dysfunction adversely effects multiple functional outcomes and social roles after TBI. We hypothesize that chronic systemic inflammation exacerbates cognitive deficits post-injury and diminishes functional cognition and quality
Externí odkaz:
https://doaj.org/article/2a3e5b5719f440ab8ecb301f7438de6a
Autor:
Mingkuan Lin, Wan Huang, Nadine Kabbani, Mark M Theiss, John F Hamilton, James M Ecklund, Yvette P Conley, Yoram Vodovotz, David Brienza, Amy K Wagner, Emily Robbins, Gwendolyn A Sowa, Robert H Lipsky
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251110 (2021)
The α7 neuronal nicotinic acetylcholine receptors (α7nAChRs) are essential for anti-inflammatory responses. The human-specific CHRFAM7A gene and its 2bp deletion polymorphism (Δ2bp variant) encodes a structurally-deficient α7nAChRs that may impac
Externí odkaz:
https://doaj.org/article/4a386b81cf444528804f9e1a7194413f
Autor:
Lauren B. Fisher, Joshua E. Curtiss, Daniel W. Klyce, Paul B. Perrin, Shannon B. Juengst, Kelli W. Gary, Janet P. Niemeier, Flora M. Hammond, Thomas F. Bergquist, Amy K. Wagner, Amanda R. Rabinowitz, Joseph T. Giacino, Ross D. Zafonte
Publikováno v:
American Journal of Physical Medicine & Rehabilitation. 102:137-143
Autor:
Shraddha, Mainali, Venkatesh, Aiyagari, Sheila, Alexander, Yelena, Bodien, Varina, Boerwinkle, Melanie, Boly, Emery, Brown, Jeremy, Brown, Jan, Claassen, Brian L, Edlow, Ericka L, Fink, Joseph J, Fins, Brandon, Foreman, Jennifer, Frontera, Romergryko G, Geocadin, Joseph, Giacino, Emily J, Gilmore, Olivia, Gosseries, Flora, Hammond, Raimund, Helbok, J, Claude Hemphill, Karen, Hirsch, Keri, Kim, Steven, Laureys, Ariane, Lewis, Geoffrey, Ling, Sarah L, Livesay, Victoria, McCredie, Molly, McNett, David, Menon, Erika, Molteni, DaiWai, Olson, Kristine, O'Phelan, Soojin, Park, Len, Polizzotto, Jose, Javier Provencio, Louis, Puybasset, Chethan P, Venkatasubba Rao, Courtney, Robertson, Benjamin, Rohaut, Michael, Rubin, Tarek, Sharshar, Lori, Shutter, Gisele, Sampaio Silva, Wade, Smith, Robert D, Stevens, Aurore, Thibaut, Paul, Vespa, Amy K, Wagner, Wendy C, Ziai, Elizabeth, Zink, Jose, I Suarez
Publikováno v:
Neurocritical Care, Vol. 37, No. 1
This proceedings article presents actionable research targets on the basis of the presentations and discussions at the 2nd Curing Coma National Institutes of Health (NIH) symposium held from May 3 to May 5, 2021. Here, we summarize the background, re
Autor:
Janet P. Niemeier, Paul B. Perrin, Bradley S. Hurst, David M. Foureau, Toan T. Huynh, Susan L. Evans, Jonathan E. Silverman, M. Elise McClannahan, Benjamin D. Brusch, Mark Newman, Jean-Luc Mougeot, Amy K. Wagner
Publikováno v:
Behavioural Neurology, Vol 2019 (2019)
Objective. To compare baseline and 72-hour hormone levels in women with traumatic brain injury (TBI) and controls. Setting. Hospital emergency department. Participants. 21 women ages 18-35 with TBI and 21 controls. Design. Repeated measures. Main Mea
Externí odkaz:
https://doaj.org/article/7ddc6f357f614683a055379ed0d71e1e
Autor:
Kelli W. Gary, Charles H. Bombardier, Paul B. Perrin, Amanda R. Rabinowitz, Lauren B. Fisher, Amy K. Wagner, Janet P. Niemeier, Ross Zafonte, Shannon B. Juengst, Daniel W. Klyce, Thomas F. Bergquist, Flora M. Hammond
Publikováno v:
Archives of Physical Medicine and Rehabilitation. 103:69-74
Objective To investigate relative causality in relations among suicidal ideation (SI), depressive symptoms, and functional independence over the first 10 years after traumatic brain injury (TBI). Design Prospective longitudinal design with data colle