Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Amy K, Schmid"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 1, p e1011115 (2024)
Timely regulation of carbon metabolic pathways is essential for cellular processes and to prevent futile cycling of intracellular metabolites. In Halobacterium salinarum, a hypersaline adapted archaeon, a sugar-sensing TrmB family protein controls gl
Externí odkaz:
https://doaj.org/article/362b84a28a6c47408fb7e8de14b2a2d4
Autor:
Saaz Sakrikar, Rylee K. Hackley, Mar Martinez-Pastor, Cynthia L. Darnell, Angie Vreugdenhil, Amy K. Schmid
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Histone proteins are found across diverse lineages of Archaea, many of which package DNA and form chromatin. However, previous research has led to the hypothesis that the histone-like proteins of high-salt-adapted archaea, or halophiles, fun
Externí odkaz:
https://doaj.org/article/a4187bde4b9b4b7db7785a08bc9b4fbd
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 682 (2022)
Despite intense recent research interest in archaea, the scientific community has experienced a bottleneck in the study of genome-scale gene expression experiments by RNA-seq due to the lack of commercial and specifically designed rRNA depletion kits
Externí odkaz:
https://doaj.org/article/ac4472e787214119a09b6ee13e99f449
Autor:
Peter D Tonner, Cynthia L Darnell, Francesca M L Bushell, Peter A Lund, Amy K Schmid, Scott C Schmidler
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008366 (2020)
Substantive changes in gene expression, metabolism, and the proteome are manifested in overall changes in microbial population growth. Quantifying how microbes grow is therefore fundamental to areas such as genetics, bioengineering, and food safety.
Externí odkaz:
https://doaj.org/article/bfd34c3824224212846d9bc76d435aaf
Autor:
Cynthia L. Darnell, Jenny Zheng, Sean Wilson, Ryan M. Bertoli, Alexandre W. Bisson-Filho, Ethan C. Garner, Amy K. Schmid
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Precise control of the cell cycle is central to the physiology of all cells. In prior work we demonstrated that archaeal cells maintain a constant size; however, the regulatory mechanisms underlying the cell cycle remain unexplored in this d
Externí odkaz:
https://doaj.org/article/efe91ec2cd5b4204ab3646133fe6130f
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Halobacterium salinarum are halophilic archaea that display directional swimming in response to various environmental signals, including light, chemicals and oxygen. In Hbt. salinarum, the building blocks (archaellins) of the archaeal swimming appara
Externí odkaz:
https://doaj.org/article/d342a1d1201549a588c899bf2ec71c1a
Publikováno v:
Frontiers in Microbiology, Vol 9 (2019)
Different weak organic acids have significant potential as topical treatments for wounds infected by opportunistic pathogens that are recalcitrant to standard treatments. These acids have long been used as bacteriostatic compounds in the food industr
Externí odkaz:
https://doaj.org/article/3ec132b6fef34e549511f6fe373d8fee
Autor:
Christine Vogel, Gábor Balázsi, Alexander Löwer, Caifu Jiang, Amy K. Schmid, Morten Sommer, Laurence Yang, Christian Münch, Andrew Wang, Kavita Israni-Winger, Timo Mühlhaus, David L. Des Marais, Henrik Oster, Merav Socolovsky
Publikováno v:
Cell Systems. 13:195-200
Autor:
Ian C McDowell, Dinesh Manandhar, Christopher M Vockley, Amy K Schmid, Timothy E Reddy, Barbara E Engelhardt
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 1, p e1005896 (2018)
Transcriptome-wide time series expression profiling is used to characterize the cellular response to environmental perturbations. The first step to analyzing transcriptional response data is often to cluster genes with similar responses. Here, we pre
Externí odkaz:
https://doaj.org/article/d9761a1f0fdd45228f30355b32b4f1e1
Publikováno v:
mSystems, Vol 2, Iss 5 (2017)
ABSTRACT Gene regulatory networks (GRNs) are critical for dynamic transcriptional responses to environmental stress. However, the mechanisms by which GRN regulation adjusts physiology to enable stress survival remain unclear. Here we investigate the
Externí odkaz:
https://doaj.org/article/3bbdaf3a09eb4d9082a1bd61dc3fcd72