Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Amy Joehlin‐Price"'
Autor:
Rashmi Bharti, Goutam Dey, Debjit Khan, Alex Myers, Olivia G. Huffman, Caner Saygin, Chad Braley, Elliott Richards, Naseer Sangwan, Belinda Willard, Justin D. Lathia, Paul L. Fox, Feng Lin, Babal Kant Jha, J. Mark Brown, Jennifer S. Yu, Mohammed Dwidar, Amy Joehlin-Price, Roberto Vargas, Chad M. Michener, Michelle S. Longworth, Ofer Reizes
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-23 (2024)
Abstract Background Platinum resistance is the primary cause of poor survival in ovarian cancer (OC) patients. Targeted therapies and biomarkers of chemoresistance are critical for the treatment of OC patients. Our previous studies identified cell su
Externí odkaz:
https://doaj.org/article/adfec356b7014a638df6edb322f5b4fb
Autor:
Goutam Dey, Rashmi Bharti, Chad Braley, Ravi Alluri, Emily Esakov, Katie Crean-Tate, Keith McCrae, Amy Joehlin-Price, Peter G. Rose, Justin Lathia, Zihua Gong, Ofer Reizes
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-19 (2023)
Abstract Poly-ADP Ribose Polymerase (PARP) targeted therapy is clinically approved for the treatment of homologous recombination (HR) repair deficient tumors. The remarkable success of this therapy in the treatment of HR repair deficient cancers has
Externí odkaz:
https://doaj.org/article/2717acaed3114fb5964d7b172163769d
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3545-3558 (2021)
High‐grade neuroendocrine carcinoma of gynecologic origin (NEC‐GYN) is a highly aggressive cancer that often affects young women. The clinical management of NEC‐GYN is typically extrapolated from its counterpart, small cell carcinoma of the lun
Externí odkaz:
https://doaj.org/article/ffae59a46950433a8f22dbd047b6eba3
Autor:
Ying Ni, Ahmed Soliman, Amy Joehlin-Price, Peter G. Rose, Anda Vlad, Robert P. Edwards, Haider Mahdi
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-11 (2021)
Abstract Various immune signatures predictive of resistance to immune checkpoint inhibitors (ICI) have been described in multiple solid cancers, but still under-investigated in gynecological (GYN) cancer. For 49 GYN cancer patients included in our st
Externí odkaz:
https://doaj.org/article/3f72a09e25c04f2ea9c7be83e5af3188
Autor:
Pingfu Fu, Kaustav Bera, Anant Madabhushi, Haider Mahdi, Germán Corredor, Sepideh Azarianpour, Patrick Leo, Paula Toro, Amy Joehlin-Price, Mojgan Mokhtari
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background We present a computational approach (ArcTIL) for quantitative characterization of the architecture of tumor-infiltrating lymphocytes (TILs) and their interplay with cancer cells from digitized H&E-stained histology whole slide images and e
Externí odkaz:
https://doaj.org/article/5d5121298d5b47439230a95deaf72537
Autor:
Jonathan T. Hunt, Laura M. Chambers, Meng Yao, Amy Joehlin-Price, Robert Debernardo, Peter G. Rose
Publikováno v:
Gynecologic Oncology Reports, Vol 37, Iss , Pp 100840- (2021)
Objective(s): To investigate the efficacy of pembrolizumab plus lenvatinib as a second-line or later-line therapy in women with advanced or recurrent uterine carcinosarcoma (UCS). Methods: A single-institution pharmacy database was queried for women
Externí odkaz:
https://doaj.org/article/c46ab3e278b6456fb18b9f4971ae7015
Autor:
Ata Abbas, Morgan Gruner, Jennifer Karohl, Peter G. Rose, Amy Joehlin-Price, Daniel Stover, Haider Mahdi
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Neuroendocrine carcinoma of the cervix is a rare and aggressive form of cervical cancer that presents with frequent metastasis at diagnosis and high recurrence rates. Primary treatment is multimodal, which often includes chemotherapy with or without
Externí odkaz:
https://doaj.org/article/ea9756269e1145a893cdee946c8898da
Predictors of response to immune checkpoint inhibition in a real world gynecologic cancer population
Autor:
Michelle L. Kuznicki, Carrie Bennett, Meng Yao, Amy Joehlin-Price, Peter G. Rose, Haider Mahdi
Publikováno v:
Gynecologic Oncology Reports, Vol 34, Iss , Pp 100671- (2020)
Prognostic factors for immune checkpoint inhibitor (CPI) response in gynecologic cancer are limited. This retrospective study aimed to identify prognostic factors associated with improved overall response rate (ORR) and progression free survival (PFS
Externí odkaz:
https://doaj.org/article/d47f0383948d44cfa6684e5bfebdf536
Publikováno v:
Case Reports in Endocrinology, Vol 2016 (2016)
Objective. Thyroid disease has been reported among the endocrinopathies that can occur after treatment with ipilimumab. Graves’ disease, however, has been rarely reported with this medication. Here we report a case of Graves’ disease diagnosed af
Externí odkaz:
https://doaj.org/article/050166b2c3204f0ba72973fc5955a97a
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3545-3558 (2021)
Molecular Oncology
Molecular Oncology
High‐grade neuroendocrine carcinoma of gynecologic origin (NEC‐GYN) is a highly aggressive cancer that often affects young women. The clinical management of NEC‐GYN is typically extrapolated from its counterpart, small cell carcinoma of the lun