Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Amy J. Hanson"'
Publikováno v:
BioTechniques, Vol 34, Iss 5, Pp 958-968 (2003)
Tetracycline controlled gene expression varies significantly among cells within a cell line. Chromosomal integration sites of the tetracycline transactivator (tTA) gene and/or the test gene presumably account for the variable efficacy of this system.
Externí odkaz:
https://doaj.org/article/377b09e983c64b6f9817188db6a3967a
Autor:
Kedar N. Prasad, Piruz Nahreini, Cynthia Andreatta, Judith E. Prasad, Amy J. Hanson, Bipin Kumar
Publikováno v:
Journal of the American College of Nutrition. 24:516-523
High levels of wild-type alpha-synuclein are found in autopsied brain samples of idiopathic Parkinson's disease (PD), some familial PD, some Alzheimer's disease (AD) and Down's syndrome with dementia. Therefore, we have investigated whether overexpre
Publikováno v:
Oncogene. 24:4149-4154
Gene-silencing activity mediated by siRNA has been demonstrated in mammalian cells; however, the mechanism of its regulation is not well understood. Since downregulation of a number of genes occurs during adenosine 3',5'-cyclic monophosphate (cAMP)-i
Publikováno v:
Cellular and Molecular Neurobiology. 24:781-792
1. RNA interference (RNAi) is a multicomponent machinery that operates in a sequence-specific manner to repress the expression of genes in most eukaryotic cells. 2. Here we wanted to investigate in a murine neuroblastoma cell line (NBP2) (a) if repla
Publikováno v:
Journal of Neuroscience Research. 78:570-579
Highly malignant neuroblastoma tumors generally have defects in differentiation and apoptotic pathways. For a better understanding of these events, we use a murine neuroblastoma cell line (NBP2) that terminally differentiates into mature neurons in r
α-Tocopheryl Succinate, the Most Effective Form of Vitamin E for Adjuvant Cancer Treatment: A Review
Publikováno v:
Journal of the American College of Nutrition. 22:108-117
In 1982, it was established that alpha-tocopheryl succinate (alpha-TS) was the most effective form of vitamin E in comparison to alpha-tocopherol, alpha-tocopheryl acetate and alpha-tocopheryl nicotinate in inducing differentiation, inhibition of pro
Autor:
Piruz Nahreini, Bipin Kumar, Judith Edwards-Prasad, Amy J. Hanson, Cynthia Andreatta, Curt R. Freed, Kedar N. Prasad
Publikováno v:
Cellular and Molecular Neurobiology. 23:27-42
1. The limited lifespan of human embryonic brain (HEB) cells hampers their therapeutic use for the treatment of neurodegenerative diseases.
Publikováno v:
Journal of Neuro-Oncology. 63:15-23
Proteasome activity is essential during cAMP-induced terminal differentiation of a murine neuroblastoma cell line (NBP2). However, the mechanisms through which proteasome affects NBP2 differentiation have not been characterized. We hypothesized that
Autor:
Bipin Kumar, Xiang-Dong Yan, Kedar N. Prasad, Amy J. Hanson, Judith E. Prasad, Piruz Nahreini
Publikováno v:
Journal of neuroscience research. 81(1)
Prostaglandin E2 (PGE2), one product of inflammatory reactions, and PGA1, which is formed during PGE2 extraction, induce degeneration in adenosine 3′,5′-cyclic monophosphate (cAMP)-induced differentiated neuroblastoma (NB) cells in culture. The m
Autor:
Kedar N. Prasad, Judith E. Prasad, Xiang Dong Yan, Amy J. Hanson, Cynthia Andreatta, Bipin Kumar, Piruz Nahreini
Publikováno v:
Journal of neuroscience research. 76(3)
Increased accumulation of alpha-synuclein is associated with certain neurodegenerative diseases including Parkinson's disease (PD) and Alzheimer's disease (AD). One mechanism of alpha-synuclein-induced toxicity involves increased oxidative stress. It