Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Amy J. Conway"'
Autor:
Steven P. Maher, Amélie Vantaux, Victor Chaumeau, Adeline C. Y. Chua, Caitlin A. Cooper, Chiara Andolina, Julie Péneau, Mélanie Rouillier, Zaira Rizopoulos, Sivchheng Phal, Eakpor Piv, Chantrea Vong, Sreyvouch Phen, Chansophea Chhin, Baura Tat, Sivkeng Ouk, Bros Doeurk, Saorin Kim, Sangrawee Suriyakan, Praphan Kittiphanakun, Nana Akua Awuku, Amy J. Conway, Rays H. Y. Jiang, Bruce Russell, Pablo Bifani, Brice Campo, François Nosten, Benoît Witkowski, Dennis E. Kyle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several com
Externí odkaz:
https://doaj.org/article/82bd81cce09f483dac02985c053a9b50
Autor:
Alison Roth, Steven P. Maher, Amy J. Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A. Kaba, Amélie Vantaux, Malina A. Bakowski, Richard Thomson-Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J. Barnes, Caitlin A. Cooper, Mélanie Rouillier, Case W. McNamara, Sebastian A. Mikolajczak, Noah Sather, Benoît Witkowski, Brice Campo, Stefan H. I. Kappe, David E. Lanar, François Nosten, Silas Davidson, Rays H. Y. Jiang, Dennis E. Kyle, John H. Adams
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Currently available platforms to study liver stage of Plasmodium species have limitations. Here, the authors show that primary human hepatocyte cultures in 384-well format support hypnozoite and other liver stage development and are suitable for drug
Externí odkaz:
https://doaj.org/article/0b14f6d533014ef091394f171d42ba23
Autor:
Angela Babetski Holton, Francy L Sinatra, Jenny Kreahling, Amy J Conway, David A Landis, Soner Altiok
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169797 (2017)
The tumor microenvironment is composed of cellular and stromal components such as tumor cells, mesenchymal cells, immune cells, cancer associated fibroblasts and the supporting extracellular matrix. The tumor microenvironment provides crucial support
Externí odkaz:
https://doaj.org/article/c7e0a0050aad42d39c02be709bb97767
Autor:
Raahil S. Patel, Brice Campo, Jetsumon Sattabongkot, Steven P. Maher, Chris Palmiotti, Chiara Andolina, Rays H. Y. Jiang, Alison Roth, Phillip Cualing, Dennis E. Kyle, Jessica Turgeon, Robert Carter, John H. Adams, Swamy R. Adapa, Wajeeh M. Saadi, Virginia Van Grod, François Nosten, Amy J. Conway, Myles E. Johnson, Samantha J. Barnes, Naresh Singh, H-C Steve Sun, Victor Chaumeau, James C. Hsiao
Publikováno v:
Lab on a Chip. 20:1124-1139
Advanced cell culture methods for modeling organ-level structure have been demonstrated to replicate in vivo conditions more accurately than traditional in vitro cell culture. Given that the liver is particularly important to human health, several ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5926a5d714e8c45a09f91b21b579d0
https://doi.org/10.1039/c9lc00921c
https://doi.org/10.1039/c9lc00921c
Autor:
Alison Roth, Steven P. Maher, Amy J. Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A. Kaba, Amélie Vantaux, Malina A. Bakowski, Richard Thomson-Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J. Barnes, Caitlin A. Cooper, Mélanie Rouillier, Case W. McNamara, Sebastian A. Mikolajczak, Noah Sather, Benoît Witkowski, Brice Campo, Stefan H. I. Kappe, David E. Lanar, François Nosten, Silas Davidson, Rays H. Y. Jiang, Dennis E. Kyle, John H. Adams
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of Richard Thomson-Luque, which was incorrectly given as Richard Thomson Luque. This error has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/73adfbdede8e4de38681a2951dacd5ea
Autor:
Adeline C. Y. Chua, Saorin Kim, Bruce Russell, Eakpor Piv, Sivkeng Ouk, Rays H. Y. Jiang, Zaira Rizopoulos, Dennis E. Kyle, Sivchheng Phal, Pablo Bifani, Bros Doeurk, Amélie Vantaux, Julie Péneau, Nana Akua Awuku, Sangrawee Suriyakan, Brice Campo, Benoit Witkowski, Chansophea Chhin, Mélanie Rouillier, Sreyvouch Phen, Chantrea Vong, Praphan Kittiphanakun, Steven P. Maher, François Nosten, Chiara Andolina, Amy J. Conway, Caitlin A. Cooper, Baura Tat, Victor Chaumeau
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.19905. ⟨10.1038/s41598-021-99152-9⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.19905. ⟨10.1038/s41598-021-99152-9⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several compound lib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d351b9c26631b1545f18c69ca7cb66
https://hal-pasteur.archives-ouvertes.fr/pasteur-03491954/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03491954/document
Autor:
Case W. McNamara, Dyann F. Wirth, Francisco-Javier Gamo, Dionicio Siegel, Yevgeniya Antonova-Koch, Dennis E. Kyle, Korina Eribez, Cullin McLean Taggard, Maureen Ibanez, François Nosten, Yang Zhong, Sabine Ottilie, Edward Owen, Victor Chaumeau, Jeremy N. Burrows, Kaisheng Chen, Elizabeth A. Winzeler, Mélanie Rouillier, Madeline R. Luth, Christie Lincoln, Stephan Meister, Juan Carlos Jado, Tomoyo Sakata-Kato, David A. Fidock, Yingyao Zhou, Kerstin Gagaring, Manuel Llinás, Jaeson Calla, Biniam Ambachew, Matthew Abraham, Amanda K. Lukens, Amy J. Conway, Fernando Neria Serrano, Manu Vanaerschot, Andrea L. Cheung, Brice Campo, Steven P. Maher, David Plouffe
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Science (New York, N.Y.), vol 362, iss 6419
Science (New York, N.y.)
Consejería de Sanidad de la Comunidad de Madrid
Science (New York, N.Y.), vol 362, iss 6419
Science (New York, N.y.)
To discover leads for next-generation chemoprotective antimalarial drugs,we tested more than 500,000 compounds for their ability to inhibit liver-stage development of luciferase-expressing Plasmodium spp. parasites (681 compounds showed a half-maxima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276ca79aa5124b1a30513b1776aa4ace
https://doi.org/10.1126/science.aat9446
https://doi.org/10.1126/science.aat9446
Autor:
François Nosten, Amy J. Conway, Samantha J. Barnes, Chiara Andolina, Steven P. Maher, Richard Thomson-Luque, Naresh Singh, Alison Roth, Silas A. Davidson, David E. Lanar, Brice Campo, Swamy R. Adapa, Benoît. Witkowski, Victor Chaumeau, Ratawan Ubalee, Stefan H. I. Kappe, Mélanie Rouillier, Amélie Vantaux, Stephen A. Kaba, Sebastian A. Mikolajczak, John H. Adams, Rays H. Y. Jiang, Dennis E. Kyle, Malina A. Bakowski, Case W. McNamara, Noah Sather, Caitlin A. Cooper
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1837. ⟨10.1038/s41467-018-04221-9⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1837. ⟨10.1038/s41467-018-04221-9⟩
Malaria liver stages represent an ideal therapeutic target with a bottleneck in parasite load and reduced clinical symptoms; however, current in vitro pre-erythrocytic (PE) models for Plasmodium vivax and P. falciparum lack the efficiency necessary f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ad925cee9202e5337487d4ac4c25f3
https://ora.ox.ac.uk/objects/uuid:fea5cdfe-ecad-4f45-95b9-1b6301e4fef7
https://ora.ox.ac.uk/objects/uuid:fea5cdfe-ecad-4f45-95b9-1b6301e4fef7
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0169797 (2017)
PLoS ONE, Vol 12, Iss 1, p e0169797 (2017)
The tumor microenvironment is composed of cellular and stromal components such as tumor cells, mesenchymal cells, immune cells, cancer associated fibroblasts and the supporting extracellular matrix. The tumor microenvironment provides crucial support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2acc42cdb3bd8df7a6f830e0496b9729
https://pubmed.ncbi.nlm.nih.gov/28085924
https://pubmed.ncbi.nlm.nih.gov/28085924
Autor:
Brice Campo, Victor Chaumeau, David E. Lanar, Chiara Andolina, Caitlin A. Cooper, Stephen A. Kaba, Ratawan Ubalee, Stefan H. I. Kappe, François Nosten, Samantha J. Barnes, Rays H. Y. Jiang, Steven P. Maher, Sebastian A. Mikolajczak, Dennis E. Kyle, Malina A. Bakowski, Naresh Singh, Amy J. Conway, Richard Thomson-Luque, Noah Sather, John H. Adams, Alison Roth, Case W. McNamara, Amélie Vantaux, Silas A. Davidson, Benoît. Witkowski, Swamy R. Adapa, Mélanie Rouillier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications
Nature Communications
Malaria liver stages represent an ideal therapeutic target with a bottleneck in parasite load and reduced clinical symptoms; however, current in vitro pre-erythrocytic (PE) models for Plasmodium vivax and P. falciparum lack the efficiency necessary f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3463fa49352a423c05cd5b2c52f9f984
http://link.springer.com/article/10.1038/s41467-018-04817-1
http://link.springer.com/article/10.1038/s41467-018-04817-1