Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Amy J Naylor"'
Autor:
Amy J Naylor, Simon W Jones, Liam M Grover, Thomas Nicholson, James Edwards, Kieran Patrick, Jonathan W Lewis, Hannah C Lamont, Kathryn Frost, Binal Patel, Miruna Chipara, Laurence A Hill, Georgiana Neag, Melissa Finlay
Publikováno v:
F1000Research, Vol 12 (2024)
Background There are insufficient in vitro bone models that accommodate long-term culture of osteoblasts and support their differentiation to osteocytes. The increased demand for effective therapies for bone diseases, and the ethical requirement to r
Externí odkaz:
https://doaj.org/article/6df289861d374cf88443e970916419f1
Autor:
Amy J Naylor, Simon W Jones, Liam M Grover, Thomas Nicholson, James Edwards, Kieran Patrick, Jonathan W Lewis, Hannah C Lamont, Kathryn Frost, Binal Patel, Miruna Chipara, Laurence A Hill, Georgiana Neag, Melissa Finlay
Publikováno v:
F1000Research, Vol 12 (2024)
Background There are insufficient in vitro bone models that accommodate long-term culture of osteoblasts and support their differentiation to osteocytes. The increased demand for effective therapies for bone diseases, and the ethical requirement to r
Externí odkaz:
https://doaj.org/article/b76abd1f90334018a55f178824171e2b
Autor:
Kieran Patrick, Xiang Tian, David Cartwright, Silke Heising, Matthew S Glover, Ellie N Northall, Lisa Cazares, Sonja Hess, David Baker, Christopher Church, Graeme Davies, Gareth Lavery, Amy J Naylor
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284012 (2023)
Cd248 has recently been associated with adipose tissue physiology, demonstrated by reduced weight gain in high fat diet-fed mice with genetic deletion of Cd248 relative to controls. Here we set out to determine the metabolic consequences of loss of C
Externí odkaz:
https://doaj.org/article/cae256c32e144dc28049e61616c1efbe
Publikováno v:
Swiss Medical Weekly, Vol 150, Iss 0506 (2020)
Although the impact of osteoblast-osteoclast crosstalk in bone remodelling has been intensively studied, the importance of osteocytes, descendants of osteoblasts, in this process has for a long time been neglected. During their embedding phase, osteo
Externí odkaz:
https://doaj.org/article/79c72035fa2d4676a06e844adcb31dd5
Autor:
Amy J Naylor, Helen M McGettrick, William D Maynard, Philippa May, Francesca Barone, Adam P Croft, Stuart Egginton, Christopher D Buckley
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107146 (2014)
CD248 (Endosialin) is a type 1 membrane protein involved in developmental and pathological angiogenesis through its expression on pericytes and regulation of PDGFRβ signalling. Here we explore the function of CD248 in skeletal muscle angiogenesis. T
Externí odkaz:
https://doaj.org/article/891a64c1198f4ce3ab1690c7bde40890
Autor:
Chloe G Fenton, Ana Crastin, Claire S Martin, Saicharan Suresh, Isabella Montagna, Bismah Hussain, Amy J Naylor, Simon W Jones, Morten S Hansen, Caroline M Gorvin, Maria Price, Andrew Filer, Mark S Cooper, Gareth G Lavery, Karim Raza, Rowan S Hardy
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7334
Therapeutic glucocorticoids (GCs) are powerful anti-inflammatory tools in the management of chronic inflammatory diseases such as rheumatoid arthritis (RA). However, their actions on bone in this context are complex. The enzyme 11β-hydroxysteroid de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c65c4bf96ba1c70ece287e1ba71d565
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7253, p 7253 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 7253, p 7253 (2021)
Interaction between endothelial cells and osteoblasts is essential for bone development and homeostasis. This process is mediated in large part by osteoblast angiotropism, the migration of osteoblasts alongside blood vessels, which is crucial for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3ea093d4f2fbca22326f164df7f66e
http://europepmc.org/articles/PMC8305002
http://europepmc.org/articles/PMC8305002
Autor:
Neil Loftus, Christopher D. Buckley, G. Ed Rainger, Ian D. Wilson, Gareth G. Lavery, Kieran Patrick, Matthew J. Harrison, Emily G. Armitage, Amy J. Naylor, Janak Bechar, Alan Barnes
Publikováno v:
Metabolomics
Introduction The Endosialin/CD248/TEM1 protein is expressed in adipose tissue and its expression increases with obesity. Recently, genetic deletion of CD248 has been shown to protect mice against atherosclerosis on a high fat diet. Objectives We inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d677cd57fe317c9845c98b5d8a76e0ad
https://ora.ox.ac.uk/objects/uuid:4c61148f-b7bc-4afe-8160-78e388926193
https://ora.ox.ac.uk/objects/uuid:4c61148f-b7bc-4afe-8160-78e388926193
Publikováno v:
Swiss Medical Weekly.
Although the impact of osteoblast-osteoclast crosstalk in bone remodelling has been intensively studied, the importance of osteocytes, descendants of osteoblasts, in this process has for a long time been neglected. During their embedding phase, osteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3058ec0abc3103982cdf3b939ef6462
https://doi.org/10.4414/smw.2020.20187
https://doi.org/10.4414/smw.2020.20187
A suspended layer additive manufacturing approach to the bioprinting of tri-layered skin equivalents
Autor:
Alan M. Smith, Miruna Chipara, Thomas E. Robinson, Jessica J. Senior, Richard J. A. Moakes, Anthony D. Metcalfe, Aleksandar Atansov, Amy J. Naylor, Liam M. Grover
Publikováno v:
APL Bioengineering, Vol 5, Iss 4, Pp 046103-046103-11 (2021)
APL Bioengineering
APL Bioengineering
Skin exhibits a complex structure consisting of three predominant layers (epidermis, dermis, and hypodermis). Extensive trauma may result in the loss of these structures and poor repair, in the longer term, forming scarred tissue and associated reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964909a2cb93a1802cf48ea2c6f7837a
https://doaj.org/article/e54a56e99b5148349b07769d429ea532
https://doaj.org/article/e54a56e99b5148349b07769d429ea532