Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Amy J Funk"'
Autor:
Chengcheng Liu, Laura J Janke, Jitesh D Kawedia, Laura B Ramsey, Xiangjun Cai, Leonard A Mattano, Kelli L Boyd, Amy J Funk, Mary V Relling
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151433 (2016)
Osteonecrosis is a common dose-limiting toxicity of glucocorticoids. Data from clinical trials suggest that other medications can increase the risk of glucocorticoid-induced osteonecrosis. Here we utilized a mouse model to study the effect of asparag
Externí odkaz:
https://doaj.org/article/99df12c3602f4a46b214c282a3d3223f
Autor:
Christopher DeRenzo, Lindsay J. Talbot, Stephen Gottschalk, Amy J. Funk, Aaron Ross, Heather Tillman, Ashley Chabot, Jessica Wagner, Phuong Nguyen, Andrew M. Davidoff
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
The outcome for metastatic pediatric osteosarcoma (OS) remains poor. Thus, there is an urgent need to develop novel therapies, and immunotherapy with CAR T cells has the potential to meet this challenge. However, there is a lack of preclinical models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587da69f68df8369f7d732d901dbdc5d
http://europepmc.org/articles/PMC8239305
http://europepmc.org/articles/PMC8239305
Publikováno v:
Vet Pathol
The NOD.Cg- Prkdcscid Il2rgtm1Wjl/SzJ strain (NOD scid gamma, NSG) is a severely immunodeficient inbred laboratory mouse used for preclinical studies because it is amenable to engraftment with human cells. Combining scid and Il2rgnull mutations resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0cf2baea0f9c35d3185472f2871e61
https://doi.org/10.1177/0300985819882631
https://doi.org/10.1177/0300985819882631
Autor:
Vinay M. Daryani, Amy J. Funk, Cori Bradley, Christopher Calabrese, Amos Hong Pheng Loh, David Ross Goshorn, Armita Bahrami, Clinton F. Stewart, Michael A. Dyer, Xiang Chen, Peter Vogel, Elizabeth Stewart, Asa Karlstrom, Fred Krafcik, Greg Miller, Anang A. Shelat
Publikováno v:
Cancer letters. 442
Lead discovery in osteosarcoma has been hampered by the lack of new agents, limited representative clinical samples and paucity of accurate preclinical models. We developed orthotopic patient-derived xenografts (PDXs) that recapitulated the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9be97c7ff2053addaeaf250f430f58
https://pubmed.ncbi.nlm.nih.gov/30395907
https://pubmed.ncbi.nlm.nih.gov/30395907
Autor:
Laura J. Janke, Peter Vogel, Amy J. Funk, Chengcheng Liu, Jitesh D. Kawedia, Mary V. Relling, Kelli L. Boyd
Publikováno v:
The American Journal of Pathology. 183:19-25
Patients undergoing glucocorticoid therapy for a variety of disorders, including autoimmune diseases and hematological malignancies, are at risk of developing osteonecrosis. Despite extensive research in both patients and animal models, the underlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3da1e4b6792ea11216c2ac1131d1dc
https://doi.org/10.1016/j.ajpath.2013.03.004
https://doi.org/10.1016/j.ajpath.2013.03.004
Publikováno v:
Lab Animal. 47:54-54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9da8f0c2867e2e3fa67a6db515d3659
https://doi.org/10.1038/s41684-018-0006-y
https://doi.org/10.1038/s41684-018-0006-y
Autor:
Jerry R. Aldridge, William J. Martin, Cory Reynolds, Pradyot Dash, Amy J. Funk, Richard J. Webby, Peter C. Doherty, Mohamed Lamkanfi, Paul G. Thomas, Kelli L. Boyd, Ali H. Ellebedy, Thirumala-Devi Kanneganti
Publikováno v:
Immunity. 30(4):566-575
Virus-induced IL-1β and IL-18 production in macrophages is mediated via a caspase-1 pathway. Multiple microbial components, including viral RNA, are thought to trigger assembly of the cryopyrin inflammasome and consequent caspase-1 activation. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220dc884b2258e92f4bdbccb61148fc5
Autor:
Beverley Ann Alderton, Jonathan W. Ball, Alberto Rodriguez Barbon, Margaret Batchelder, Hugues Beaufrère, Michelle Bingley, Michael C. Blanco, Teresa Bradley Bays, Cynthia J. Brown, Anne Burgdorf-Moisuk, Michael V. Campagna, Michelle L. Campbell-Ward, Brendan Carmel, Cathy T.T. Chan, Jaime Chin, John Chitty, Deborah Cottrell, David A. Crum, Julie DeCubellis, Stephen J. Divers, Thomas M. Donnelly, Michael Dutton, Will Easson, David Eshar, Brian A. Evans, Peter G. Fischer, James G. Fox, Amy J. Funk, Alexis García, Jennifer Graham, Caroline Hahn, Katleen Hermans, Candace Hersey-Benner, Gretta Howard, Gwendolyn R. Jankowski, Emma Keeble, Dominique L. Keller, Peter Kerr, Sharron M. Kirchain, Megan Kirchgessner, La'Toya Latney, John Henry Lewington, Brad A. Lock, Rebecca L. Malakoff, Caralee Manley, Christoph Mans, Robert P. Marini, Jorge Martínez, Jörg Mayer, Anna Meredith, Huynh Minh, Mark A. Mitchell, Holly S. Mullen, Jason Norman, Brian S. Palmeiro, Jean A. Paré, Mary M. Patterson, David Perpiñán, Carrie A. Phelps, Charly Pignon, Anthony A. Pilny, Chantale L. Pinard, Romain Pizzi, Christal Pollock, Lauren V. Powers, Aidan Raftery, Viviane Silva Raymundo, Drury R. Reavill, Virgina C.G. Richardson, Cecilia Robat, Helen E. Roberts, William Rosenblad, David Sanchez-Migallon Guzman, Richard A. Saunders, Shannon N. Shaw, James L. (Jay) Shelton, Alana Shrubsole-Cockwill, Nico J. Schoemaker, Jeffrey Smith, Scott J. Stahl, Simon R. Starkey, W. Michael Taylor, Thomas N. Tully, Molly Varga, David Vella, Wolf von Bomhard, Narelle Walter, James F.X. Wellehan, Cameron J.G. Whittaker, Katherine E. Whitwell, Bruce H. Williams, Kimberlee B. Wojick, Kevin M. Wright, Nicole R. Wyre, Trevor T. Zachariah
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da1689d10fab6a9ead9d453439b3fff0
https://doi.org/10.1016/b978-1-4160-3969-3.00428-5
https://doi.org/10.1016/b978-1-4160-3969-3.00428-5
Autor:
Xiangjun Cai, Leonard A. Mattano, Mary V. Relling, Laura B. Ramsey, Kelli L. Boyd, Laura J. Janke, Amy J. Funk, Chengcheng Liu, Jitesh D. Kawedia
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151433 (2016)
PLoS ONE
PLoS ONE
Osteonecrosis is a common dose-limiting toxicity of glucocorticoids. Data from clinical trials suggest that other medications can increase the risk of glucocorticoid-induced osteonecrosis. Here we utilized a mouse model to study the effect of asparag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c29beb29de227972d13f05d7b90e17e
https://doi.org/10.1371/journal.pone.0151433
https://doi.org/10.1371/journal.pone.0151433
Autor:
Amy J, Funk, Timothy D, Mandrell, Sharon J, Lokey, Stanley D, Kosanke, Chin-Shang, Li, Charles F, Potters
Publikováno v:
Comparative medicine. 57(2)
Assisted ventilation is necessary for treating preterm infants with respiratory distress syndrome. Unfortunately, high and prolonged concentrations of oxygen associated with assisted ventilation often lead to pulmonary changes, such as hemorrhage and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a03c480c1ccc654a41f5db5275df333
https://pubmed.ncbi.nlm.nih.gov/17536619
https://pubmed.ncbi.nlm.nih.gov/17536619