Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Amy J, Eshleman"'
Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists
Autor:
Dilip K. Tosh, Antonella Ciancetta, Philip Mannes, Eugene Warnick, Aaron Janowsky, Amy J. Eshleman, Elizabeth Gizewski, Tarsis F. Brust, Laura M. Bohn, John A. Auchampach, Zhan-Guo Gao, Kenneth A. Jacobson
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 12658-12678 (2018)
Externí odkaz:
https://doaj.org/article/1e1f1e1e4506436da0e5c5de6c1ad211
Autor:
Ewa Galaj, Guo-Hua Bi, Benjamin Klein, Briana Hempel, Anver Basha Shaik, Emma S. Gogarnoiu, Jacob Friedman, Jenny Lam, Rana Rais, John F. Reed, Shelley H. Bloom, Tracy L. Swanson, Jennifer L. Schmachtenberg, Amy J. Eshleman, Aaron Janowsky, Zheng-Xiong Xi, Amy Hauck Newman
Publikováno v:
Neuropsychopharmacology. 47:2309-2318
Autor:
Laura B. Kozell, Amy J. Eshleman, Tracy L. Swanson, Shelley H. Bloom, Katherine M. Wolfrum, Jennifer L. Schmachtenberg, Randall J. Olson, Aaron Janowsky, Atheir I. Abbas
Publikováno v:
J Pharmacol Exp Ther
Novel psychoactive substances, including synthetic substituted tryptamines, represent a potential public health threat. Additionally, some substituted tryptamines are being studied under medical guidance as potential treatments of psychiatric disorde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c873bdb6d466b99885f6445a49a7ca
https://europepmc.org/articles/PMC10029822/
https://europepmc.org/articles/PMC10029822/
Publikováno v:
The FASEB Journal. 36
Autor:
Ewa, Galaj, Guo-Hua, Bi, Benjamin, Klein, Briana, Hempel, Anver Basha, Shaik, Emma S, Gogarnoiu, Jacob, Friedman, Jenny, Lam, Rana, Rais, John F, Reed, Shelley H, Bloom, Tracy L, Swanson, Jennifer L, Schmachtenberg, Amy J, Eshleman, Aaron, Janowsky, Zheng-Xiong, Xi, Amy Hauck, Newman
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 47(13)
The non-medical use of opioids has become a national crisis in the USA. Developing non-opioid pharmacotherapies for controlling this opioid epidemic is urgent. Dopamine D
Autor:
Xiao Shi, Nicole A R Walter, John H Harkness, Kim A Neve, Robert W Williams, Lu Lu, John K Belknap, Amy J Eshleman, Tamara J Phillips, Aaron Janowsky
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152581 (2016)
Methamphetamine (MA) and neurotransmitter precursors and metabolites such as tyramine, octopamine, and β-phenethylamine stimulate the G protein-coupled trace amine-associated receptor 1 (TAAR1). TAAR1 has been implicated in human conditions includin
Externí odkaz:
https://doaj.org/article/7030c05efd874274b2cf2d34ae5accc5
Autor:
Jennifer L. Schmachtenberg, John F. Reed, Randy Torralva, Tracy L. Swanson, William E. Schutzer, Katherine M. Wolfrum, Amy J. Eshleman, Shelley H. Bloom, Aaron Janowsky
Publikováno v:
J Pharmacol Exp Ther
Synthetic opioids, including fentanyl and its analogs, have therapeutic efficacy in analgesia and anesthesia. However, their illicit use in the United States has increased and contributed to the number one cause of death for adults 18–50 years old.
Publikováno v:
The FASEB Journal. 35
Autor:
John F. Reed, Aaron Janowsky, Robert A. Johnson, Katherine M. Wolfrum, Sunyoung O. Kim, Amy J. Eshleman
Publikováno v:
Biochemical Pharmacology. 158:27-34
The use of new psychoactive substituted 2,5-dimethoxy-N-benzylphenethylamines is associated with abuse and toxicity in the United States and elsewhere and their pharmacology is not well known. This study compares the mechanisms of action of 2(2,5-dim
Autor:
Tamara Antonio, Steven R Childers, Richard B Rothman, Christina M Dersch, Christine King, Martin Kuehne, William G Bornmann, Amy J Eshleman, Aaron Janowsky, Eric R Simon, Maarten E A Reith, Kenneth Alper
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77262 (2013)
The iboga alkaloids are a class of small molecules defined structurally on the basis of a common ibogamine skeleton, some of which modify opioid withdrawal and drug self-administration in humans and preclinical models. These compounds may represent a
Externí odkaz:
https://doaj.org/article/15dd1576a36a4ceaa239a8d0e66074b4