Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amy H. Cui"'
Autor:
Amy H. Cui, Robert P. Mecham, Marius Catalin Staiculescu, Jessica E. Wagenseil, Diana B Griffin, Austin J. Cocciolone, Jie Z Hawes
Publikováno v:
Am J Physiol Heart Circ Physiol
Elastin is a primary structural protein in the arterial wall that contributes to vascular mechanical properties and degrades with aging. Aging is associated with arterial stiffening and an increase in blood pressure. There is evidence that arterial a
Autor:
Lucie Delemotte, Jonathan R. Silva, Amy H. Cui, Kelli McFarland White, Jianmin Cui, Annie M. Westerlund, Po Wei Kang, Jingyi Shi, Alex K. Dou
Publikováno v:
Science Advances
Calmodulin controls KCNQ1 potassium channel pore opening by competing with PIP2 in the KCNQ1 voltage-sensing domain.
Calmodulin (CaM) and phosphatidylinositol 4,5-bisphosphate (PIP2) are potent regulators of the voltage-gated potassium channel K
Calmodulin (CaM) and phosphatidylinositol 4,5-bisphosphate (PIP2) are potent regulators of the voltage-gated potassium channel K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4365b3d96c48cc72e660025623c1af64
https://doi.org/10.1101/2020.07.04.187161
https://doi.org/10.1101/2020.07.04.187161
Autor:
Panpan Hou, Hong Zhan Wang, Guohui Zhang, Kelli McFarland White, Nien-Du Yang, Xiaoqin Zou, Moawiah M. Naffaa, Alex K. Dou, Ira S. Cohen, Junyuan Gao, Wenjuan Kong, Wenshan Zhao, Yongfeng Liu, Hongwu Liang, Xianjin Xu, Amy H. Cui, Jianmin Cui, Jingyi Shi
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology
Communications Biology
KCNQ family K+ channels (KCNQ1-5) in the heart, nerve, epithelium and ear require phosphatidylinositol 4,5-bisphosphate (PIP2) for voltage dependent activation. While membrane lipids are known to regulate voltage sensor domain (VSD) activation and po