Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Amy H. Buck"'
Autor:
Lewis Stevens, Isaac Martínez-Ugalde, Erna King, Martin Wagah, Dominic Absolon, Rowan Bancroft, Pablo Gonzalez de la Rosa, Jessica L. Hall, Manuela Kieninger, Agnieszka Kloch, Sarah Pelan, Elaine Robertson, Amy B. Pedersen, Cei Abreu-Goodger, Amy H. Buck, Mark Blaxter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Host-parasite interactions exert strong selection pressures on the genomes of both host and parasite. These interactions can lead to negative frequency-dependent selection, a form of balancing selection that is hypothesised to explain the hi
Externí odkaz:
https://doaj.org/article/11ee01788db84224a4f03e8a611535fa
Autor:
Ruby White, Javier Sotillo, María Eugenia Ancarola, Anne Borup, Anders Toftegaard Boysen, Paul J. Brindley, Edit I. Buzás, Serena Cavallero, Sujittra Chaiyadet, Iain W. Chalmers, Marcela A. Cucher, Maude Dagenais, Chelsea N. Davis, Eileen Devaney, Maria A. Duque‐Correa, Ramon Marc Eichenberger, Santiago Fontenla, Thomas A. Gasan, Cornelis H. Hokke, Maja Kosanovic, Marije E. Kuipers, Thewarach Laha, Alex Loukas, Rick M. Maizels, Antonio Marcilla, Hynek Mazanec, Russell M. Morphew, Kyriaki Neophytou, Linh Thuy Nguyen, Esther Nolte‐‘t Hoen, Michael Povelones, Mark W. Robinson, Alicia Rojas, Irma Schabussova, Hermelijn H. Smits, Sivapong Sungpradit, Lucienne Tritten, Bradley Whitehead, Amin Zakeri, Peter Nejsum, Amy H. Buck, Karl F. Hoffmann
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 1, Pp n/a-n/a (2023)
Abstract Over the last decade, research interest in defining how extracellular vesicles (EVs) shape cross‐species communication has grown rapidly. Parasitic helminths, worm species found in the phyla Nematoda and Platyhelminthes, are well‐recogni
Externí odkaz:
https://doaj.org/article/46a18460ff6e4def83a43ae02a7ed46f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Gastrointestinal nematodes are a diverse class of pathogens that colonise a quarter of the world’s human population and nearly all grazing livestock. These macroparasites establish, and some migrate, within host gastrointestinal niches during their
Externí odkaz:
https://doaj.org/article/fb704ae4719c464995f8be627eb64db7
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008090 (2019)
Externí odkaz:
https://doaj.org/article/3f5ae08d48a847f2a1bbba36127e6fd2
Autor:
Juan F Quintana, Sujai Kumar, Alasdair Ivens, Franklin W N Chow, Anna M Hoy, Alison Fulton, Paul Dickinson, Coralie Martin, Matthew Taylor, Simon A Babayan, Amy H Buck
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007811 (2019)
BackgroundThe release of small non-coding RNAs (sRNAs) has been reported in parasitic nematodes, trematodes and cestodes of medical and veterinary importance. However, little is known regarding the diversity and composition of sRNAs released by diffe
Externí odkaz:
https://doaj.org/article/6b1ceb9d596c48599c8d9ecf057bf4a2
Autor:
Jana L. McCaskill, Sarah Ressel, Andreas Alber, Jane Redford, Ultan F. Power, Jürgen Schwarze, Bernadette M. Dutia, Amy H. Buck
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 256-266 (2017)
The majority of antiviral therapeutics target conserved viral proteins, however, this approach confers selective pressure on the virus and increases the probability of antiviral drug resistance. An alternative therapeutic strategy is to target the ho
Externí odkaz:
https://doaj.org/article/f741a896b33f462bb461cdd3c4d5add1
Autor:
Gillian Coakley, Jana L. McCaskill, Jessica G. Borger, Fabio Simbari, Elaine Robertson, Marissa Millar, Yvonne Harcus, Henry J. McSorley, Rick M. Maizels, Amy H. Buck
Publikováno v:
Cell Reports, Vol 19, Iss 8, Pp 1545-1557 (2017)
Recent studies have demonstrated that many parasites release extracellular vesicles (EVs), yet little is known about the specific interactions of EVs with immune cells or their functions during infection. We show that EVs secreted by the gastrointest
Externí odkaz:
https://doaj.org/article/8bb9b643cf804bdaa9b018beea56deb6
Autor:
Clotilde Théry, Kenneth W Witwer, Elena Aikawa, Maria Jose Alcaraz, Johnathon D Anderson, Ramaroson Andriantsitohaina, Anna Antoniou, Tanina Arab, Fabienne Archer, Georgia K Atkin-Smith, D Craig Ayre, Jean-Marie Bach, Daniel Bachurski, Hossein Baharvand, Leonora Balaj, Shawn Baldacchino, Natalie N Bauer, Amy A Baxter, Mary Bebawy, Carla Beckham, Apolonija Bedina Zavec, Abderrahim Benmoussa, Anna C Berardi, Paolo Bergese, Ewa Bielska, Cherie Blenkiron, Sylwia Bobis-Wozowicz, Eric Boilard, Wilfrid Boireau, Antonella Bongiovanni, Francesc E Borràs, Steffi Bosch, Chantal M Boulanger, Xandra Breakefield, Andrew M Breglio, Meadhbh Á Brennan, David R Brigstock, Alain Brisson, Marike LD Broekman, Jacqueline F Bromberg, Paulina Bryl-Górecka, Shilpa Buch, Amy H Buck, Dylan Burger, Sara Busatto, Dominik Buschmann, Benedetta Bussolati, Edit I Buzás, James Bryan Byrd, Giovanni Camussi, David RF Carter, Sarah Caruso, Lawrence W Chamley, Yu-Ting Chang, Chihchen Chen, Shuai Chen, Lesley Cheng, Andrew R Chin, Aled Clayton, Stefano P Clerici, Alex Cocks, Emanuele Cocucci, Robert J Coffey, Anabela Cordeiro-da-Silva, Yvonne Couch, Frank AW Coumans, Beth Coyle, Rossella Crescitelli, Miria Ferreira Criado, Crislyn D’Souza-Schorey, Saumya Das, Amrita Datta Chaudhuri, Paola de Candia, Eliezer F De Santana, Olivier De Wever, Hernando A del Portillo, Tanguy Demaret, Sarah Deville, Andrew Devitt, Bert Dhondt, Dolores Di Vizio, Lothar C Dieterich, Vincenza Dolo, Ana Paula Dominguez Rubio, Massimo Dominici, Mauricio R Dourado, Tom AP Driedonks, Filipe V Duarte, Heather M Duncan, Ramon M Eichenberger, Karin Ekström, Samir EL Andaloussi, Celine Elie-Caille, Uta Erdbrügger, Juan M Falcón-Pérez, Farah Fatima, Jason E Fish, Miguel Flores-Bellver, András Försönits, Annie Frelet-Barrand, Fabia Fricke, Gregor Fuhrmann, Susanne Gabrielsson, Ana Gámez-Valero, Chris Gardiner, Kathrin Gärtner, Raphael Gaudin, Yong Song Gho, Bernd Giebel, Caroline Gilbert, Mario Gimona, Ilaria Giusti, Deborah CI Goberdhan, André Görgens, Sharon M Gorski, David W Greening, Julia Christina Gross, Alice Gualerzi, Gopal N Gupta, Dakota Gustafson, Aase Handberg, Reka A Haraszti, Paul Harrison, Hargita Hegyesi, An Hendrix, Andrew F Hill, Fred H Hochberg, Karl F Hoffmann, Beth Holder, Harry Holthofer, Baharak Hosseinkhani, Guoku Hu, Yiyao Huang, Veronica Huber, Stuart Hunt, Ahmed Gamal-Eldin Ibrahim, Tsuneya Ikezu, Jameel M Inal, Mustafa Isin, Alena Ivanova, Hannah K Jackson, Soren Jacobsen, Steven M Jay, Muthuvel Jayachandran, Guido Jenster, Lanzhou Jiang, Suzanne M Johnson, Jennifer C Jones, Ambrose Jong, Tijana Jovanovic-Talisman, Stephanie Jung, Raghu Kalluri, Shin-ichi Kano, Sukhbir Kaur, Yumi Kawamura, Evan T Keller, Delaram Khamari, Elena Khomyakova, Anastasia Khvorova, Peter Kierulf, Kwang Pyo Kim, Thomas Kislinger, Mikael Klingeborn, David J Klinke, Miroslaw Kornek, Maja M Kosanović, Árpád Ferenc Kovács, Eva-Maria Krämer-Albers, Susanne Krasemann, Mirja Krause, Igor V Kurochkin, Gina D Kusuma, Sören Kuypers, Saara Laitinen, Scott M Langevin, Lucia R Languino, Joanne Lannigan, Cecilia Lässer, Louise C Laurent, Gregory Lavieu, Elisa Lázaro-Ibáñez, Soazig Le Lay, Myung-Shin Lee, Yi Xin Fiona Lee, Debora S Lemos, Metka Lenassi, Aleksandra Leszczynska, Isaac TS Li, Ke Liao, Sten F Libregts, Erzsebet Ligeti, Rebecca Lim, Sai Kiang Lim, Aija Linē, Karen Linnemannstöns, Alicia Llorente, Catherine A Lombard, Magdalena J Lorenowicz, Ákos M Lörincz, Jan Lötvall, Jason Lovett, Michelle C Lowry, Xavier Loyer, Quan Lu, Barbara Lukomska, Taral R Lunavat, Sybren LN Maas, Harmeet Malhi, Antonio Marcilla, Jacopo Mariani, Javier Mariscal, Elena S Martens-Uzunova, Lorena Martin-Jaular, M Carmen Martinez, Vilma Regina Martins, Mathilde Mathieu, Suresh Mathivanan, Marco Maugeri, Lynda K McGinnis, Mark J McVey, David G Meckes, Katie L Meehan, Inge Mertens, Valentina R Minciacchi, Andreas Möller, Malene Møller Jørgensen, Aizea Morales-Kastresana, Jess Morhayim, François Mullier, Maurizio Muraca, Luca Musante, Veronika Mussack, Dillon C Muth, Kathryn H Myburgh, Tanbir Najrana, Muhammad Nawaz, Irina Nazarenko, Peter Nejsum, Christian Neri, Tommaso Neri, Rienk Nieuwland, Leonardo Nimrichter, John P Nolan, Esther NM Nolte-’t Hoen, Nicole Noren Hooten, Lorraine O’Driscoll, Tina O’Grady, Ana O’Loghlen, Takahiro Ochiya, Martin Olivier, Alberto Ortiz, Luis A Ortiz, Xabier Osteikoetxea, Ole Østergaard, Matias Ostrowski, Jaesung Park, D. Michiel Pegtel, Hector Peinado, Francesca Perut, Michael W Pfaffl, Donald G Phinney, Bartijn CH Pieters, Ryan C Pink, David S Pisetsky, Elke Pogge von Strandmann, Iva Polakovicova, Ivan KH Poon, Bonita H Powell, Ilaria Prada, Lynn Pulliam, Peter Quesenberry, Annalisa Radeghieri, Robert L Raffai, Stefania Raimondo, Janusz Rak, Marcel I Ramirez, Graça Raposo, Morsi S Rayyan, Neta Regev-Rudzki, Franz L Ricklefs, Paul D Robbins, David D Roberts, Silvia C Rodrigues, Eva Rohde, Sophie Rome, Kasper MA Rouschop, Aurelia Rughetti, Ashley E Russell, Paula Saá, Susmita Sahoo, Edison Salas-Huenuleo, Catherine Sánchez, Julie A Saugstad, Meike J Saul, Raymond M Schiffelers, Raphael Schneider, Tine Hiorth Schøyen, Aaron Scott, Eriomina Shahaj, Shivani Sharma, Olga Shatnyeva, Faezeh Shekari, Ganesh Vilas Shelke, Ashok K Shetty, Kiyotaka Shiba, Pia R-M Siljander, Andreia M Silva, Agata Skowronek, Orman L Snyder, Rodrigo Pedro Soares, Barbara W Sódar, Carolina Soekmadji, Javier Sotillo, Philip D Stahl, Willem Stoorvogel, Shannon L Stott, Erwin F Strasser, Simon Swift, Hidetoshi Tahara, Muneesh Tewari, Kate Timms, Swasti Tiwari, Rochelle Tixeira, Mercedes Tkach, Wei Seong Toh, Richard Tomasini, Ana Claudia Torrecilhas, Juan Pablo Tosar, Vasilis Toxavidis, Lorena Urbanelli, Pieter Vader, Bas WM van Balkom, Susanne G van der Grein, Jan Van Deun, Martijn JC van Herwijnen, Kendall Van Keuren-Jensen, Guillaume van Niel, Martin E van Royen, Andre J van Wijnen, M Helena Vasconcelos, Ivan J Vechetti, Tiago D Veit, Laura J Vella, Émilie Velot, Frederik J Verweij, Beate Vestad, Jose L Viñas, Tamás Visnovitz, Krisztina V Vukman, Jessica Wahlgren, Dionysios C Watson, Marca HM Wauben, Alissa Weaver, Jason P Webber, Viktoria Weber, Ann M Wehman, Daniel J Weiss, Joshua A Welsh, Sebastian Wendt, Asa M Wheelock, Zoltán Wiener, Leonie Witte, Joy Wolfram, Angeliki Xagorari, Patricia Xander, Jing Xu, Xiaomei Yan, María Yáñez-Mó, Hang Yin, Yuana Yuana, Valentina Zappulli, Jana Zarubova, Vytautas Žėkas, Jian-ye Zhang, Zezhou Zhao, Lei Zheng, Alexander R Zheutlin, Antje M Zickler, Pascale Zimmermann, Angela M Zivkovic, Davide Zocco, Ewa K Zuba-Surma
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structure
Externí odkaz:
https://doaj.org/article/6dfd3309492545d6af940b9b91fdda8e
Autor:
Fabio Simbari, Jana McCaskill, Gillian Coakley, Marissa Millar, Rick M. Maizels, Gemma Fabriás, Josefina Casas, Amy H. Buck
Publikováno v:
Journal of Extracellular Vesicles, Vol 5, Iss 0, Pp 1-16 (2016)
Extracellular vesicles (EVs) mediate communication between cells and organisms across all 3 kingdoms of life. Several reports have demonstrated that EVs can transfer molecules between phylogenetically diverse species and can be used by parasites to a
Externí odkaz:
https://doaj.org/article/204cfd2686c648059f8cba41d595cba7
Autor:
Ruby White, Javier Sotillo, María Eugenia Ancarola, Anne Borup, Anders Toftegaard Boysen, Paul J. Brindley, Edit I. Buzás, Serena Cavallero, Sujittra Chaiyadet, Iain W. Chalmers, Marcela A. Cucher, Maude Dagenais, Chelsea N. Davis, Eileen Devaney, Maria A. Duque‐Correa, Ramon Marc Eichenberger, Santiago Fontenla, Thomas A. Gasan, Cornelis H. Hokke, Maja Kosanovic, Marije E. Kuipers, Thewarach Laha, Alex Loukas, Rick M. Maizels, Antonio Marcilla, Hynek Mazanec, Russell M. Morphew, Kyriaki Neophytou, Linh Thuy Nguyen, Esther Nolte‐‘t Hoen, Michael Povelones, Mark W. Robinson, Alicia Rojas, Irma Schabussova, Hermelijn H. Smits, Sivapong Sungpradit, Lucienne Tritten, Bradley Whitehead, Amin Zakeri, Peter Nejsum, Amy H. Buck, Karl F. Hoffmann
Publikováno v:
White, R, Sotillo, J, Ancarola, M E, Borup, A, Boysen, A T, Brindley, P J, Buzás, E I, Cavallero, S, Chaiyadet, S, Chalmers, I W, Cucher, M A, Dagenais, M, Davis, C N, Devaney, E, Duque-Correa, M A, Eichenberger, R M, Fontenla, S, Gasan, T A, Hokke, C H, Kosanovic, M, Kuipers, M E, Laha, T, Loukas, A, Maizels, R M, Marcilla, A, Mazanec, H, Morphew, R M, Neophytou, K, Nguyen, L T, Nolte-'t Hoen, E, Povelones, M, Robinson, M W, Rojas, A, Schabussova, I, Smits, H H, Sungpradit, S, Tritten, L, Whitehead, B, Zakeri, A, Nejsum, P, Buck, A H & Hoffmann, K F 2023, ' Special considerations for studies of extracellular vesicles from parasitic helminths : A community-led roadmap to increase rigour and reproducibility ', Journal of Extracellular Vesicles, vol. 12, no. 1, pp. e12298 . https://doi.org/10.1002/jev2.12298
White, R, Sotillo, J, Ancarola, M E, Borup, A, Boysen, A T, Brindley, P J, Buzás, E I, Cavallero, S, Chaiyadet, S, Chalmers, I W, Cucher, M A, Dagenais, M, Davis, C N, Devaney, E, Duque-Correa, M A, Eichenberger, R M, Fontenla, S, Gasan, T A, Hokke, C H, Kosanovic, M, Kuipers, M E, Laha, T, Loukas, A, Maizels, R M, Marcilla, A, Mazanec, H, Morphew, R M, Neophytou, K, Nguyen, L T, Nolte-‘t Hoen, E, Povelones, M, Robinson, M W, Rojas, A, Schabussova, I, Smits, H H, Sungpradit, S, Tritten, L, Whitehead, B, Zakeri, A, Nejsum, P, Buck, A H & Hoffmann, K F 2023, ' Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility ', Journal of Extracellular Vesicles, vol. 12, no. 1, 12298 . https://doi.org/10.1002/jev2.12298
White, R, Sotillo, J, Ancarola, M E, Borup, A, Boysen, A T, Brindley, P J, Buzás, E I, Cavallero, S, Chaiyadet, S, Chalmers, I W, Cucher, M A, Dagenais, M, Davis, C N, Devaney, E, Duque-Correa, M A, Eichenberger, R M, Fontenla, S, Gasan, T A, Hokke, C H, Kosanovic, M, Kuipers, M E, Laha, T, Loukas, A, Maizels, R M, Marcilla, A, Mazanec, H, Morphew, R M, Neophytou, K, Nguyen, L T, Nolte-‘t Hoen, E, Povelones, M, Robinson, M W, Rojas, A, Schabussova, I, Smits, H H, Sungpradit, S, Tritten, L, Whitehead, B, Zakeri, A, Nejsum, P, Buck, A H & Hoffmann, K F 2023, ' Special considerations for studies of extracellular vesicles from parasitic helminths : A community-led roadmap to increase rigour and reproducibility ', Journal of Extracellular Vesicles, vol. 12, no. 1, 12298 . https://doi.org/10.1002/jev2.12298
Journal of Extracellular Vesicles, 12(1). WILEY
White, R, Sotillo, J, Ancarola, M E, Borup, A, Boysen, A T, Brindley, P J, Buzás, E I, Cavallero, S, Chaiyadet, S, Chalmers, I W, Cucher, M A, Dagenais, M, Davis, C N, Devaney, E, Duque-Correa, M A, Eichenberger, R M, Fontenla, S, Gasan, T A, Hokke, C H, Kosanovic, M, Kuipers, M E, Laha, T, Loukas, A, Maizels, R M, Marcilla, A, Mazanec, H, Morphew, R M, Neophytou, K, Nguyen, L T, Nolte-'t Hoen, E, Povelones, M, Robinson, M W, Rojas, A, Schabussova, I, Smits, H H, Sungpradit, S, Tritten, L, Whitehead, B, Zakeri, A, Nejsum, P, Buck, A H & Hoffmann, K F 2023, ' Special considerations for studies of extracellular vesicles from parasitic helminths : A community-led roadmap to increase rigour and reproducibility ', Journal of Extracellular Vesicles, vol. 12, no. 1, e12298 . https://doi.org/10.1002/jev2.12298
Journal of Extracellular Vesicles
White, Ruby Sotillo Gallego, Javier Ancarola, María Eugenia Marcilla Díaz, Antonio 2023 Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility Journal Of Extracellular Vesicles 12 1 e12298
White, R, Sotillo, J, Ancarola, M E, Borup, A, Boysen, A T, Brindley, P J, Buzás, E I, Cavallero, S, Chaiyadet, S, Chalmers, I W, Cucher, M A, Dagenais, M, Davis, C N, Devaney, E, Duque-Correa, M A, Eichenberger, R M, Fontenla, S, Gasan, T A, Hokke, C H, Kosanovic, M, Kuipers, M E, Laha, T, Loukas, A, Maizels, R M, Marcilla, A, Mazanec, H, Morphew, R M, Neophytou, K, Nguyen, L T, Nolte-‘t Hoen, E, Povelones, M, Robinson, M W, Rojas, A, Schabussova, I, Smits, H H, Sungpradit, S, Tritten, L, Whitehead, B, Zakeri, A, Nejsum, P, Buck, A H & Hoffmann, K F 2023, ' Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility ', Journal of Extracellular Vesicles, vol. 12, no. 1, 12298 . https://doi.org/10.1002/jev2.12298
White, R, Sotillo, J, Ancarola, M E, Borup, A, Boysen, A T, Brindley, P J, Buzás, E I, Cavallero, S, Chaiyadet, S, Chalmers, I W, Cucher, M A, Dagenais, M, Davis, C N, Devaney, E, Duque-Correa, M A, Eichenberger, R M, Fontenla, S, Gasan, T A, Hokke, C H, Kosanovic, M, Kuipers, M E, Laha, T, Loukas, A, Maizels, R M, Marcilla, A, Mazanec, H, Morphew, R M, Neophytou, K, Nguyen, L T, Nolte-‘t Hoen, E, Povelones, M, Robinson, M W, Rojas, A, Schabussova, I, Smits, H H, Sungpradit, S, Tritten, L, Whitehead, B, Zakeri, A, Nejsum, P, Buck, A H & Hoffmann, K F 2023, ' Special considerations for studies of extracellular vesicles from parasitic helminths : A community-led roadmap to increase rigour and reproducibility ', Journal of Extracellular Vesicles, vol. 12, no. 1, 12298 . https://doi.org/10.1002/jev2.12298
Journal of Extracellular Vesicles, 12(1). WILEY
White, R, Sotillo, J, Ancarola, M E, Borup, A, Boysen, A T, Brindley, P J, Buzás, E I, Cavallero, S, Chaiyadet, S, Chalmers, I W, Cucher, M A, Dagenais, M, Davis, C N, Devaney, E, Duque-Correa, M A, Eichenberger, R M, Fontenla, S, Gasan, T A, Hokke, C H, Kosanovic, M, Kuipers, M E, Laha, T, Loukas, A, Maizels, R M, Marcilla, A, Mazanec, H, Morphew, R M, Neophytou, K, Nguyen, L T, Nolte-'t Hoen, E, Povelones, M, Robinson, M W, Rojas, A, Schabussova, I, Smits, H H, Sungpradit, S, Tritten, L, Whitehead, B, Zakeri, A, Nejsum, P, Buck, A H & Hoffmann, K F 2023, ' Special considerations for studies of extracellular vesicles from parasitic helminths : A community-led roadmap to increase rigour and reproducibility ', Journal of Extracellular Vesicles, vol. 12, no. 1, e12298 . https://doi.org/10.1002/jev2.12298
Journal of Extracellular Vesicles
White, Ruby Sotillo Gallego, Javier Ancarola, María Eugenia Marcilla Díaz, Antonio 2023 Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility Journal Of Extracellular Vesicles 12 1 e12298
Over the last decade, research interest in defining how extracellular vesicles (EVs) shape cross-species communication has grown rapidly. Parasitic helminths, worm species found in the phyla Nematoda and Platyhelminthes, are well-recognised manipulat