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of 6
pro vyhledávání: '"Amy H Ponsford"'
Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis.
Autor:
Rhiannon R White, Amy H Ponsford, Michael P Weekes, Rachel B Rodrigues, David B Ascher, Marco Mol, Murray E Selkirk, Steven P Gygi, Christopher M Sanderson, Katerina Artavanis-Tsakonas
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005977 (2016)
Trichinella spiralis is a muscle-specific parasitic worm that is uniquely intracellular. T. spiralis reprograms terminally differentiated skeletal muscle cells causing them to de-differentiate and re-enter the cell cycle, a process that cannot occur
Externí odkaz:
https://doaj.org/article/984d233203c94252b6802d4833022fa0
Autor:
Jonathan Poh, Amy H. Ponsford, James Boyd, Jonathan Woodsmith, Ulrich Stelzl, Erich Wanker, Nicholas Harper, David MacEwan, Christopher M. Sanderson
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101686- (2020)
NRF2 (NFE2L2) is a cytoprotective transcription factor associated with >60 human diseases, adverse drug reactions and therapeutic resistance. To provide insight into the complex regulation of NRF2 responses, 1962 predicted NRF2-partner interactions w
Externí odkaz:
https://doaj.org/article/7cf911239b8246beb0bcaf25f01086c0
Autor:
Amy H. Ponsford, Laura E. Swan, Emanuele Cocucci, Florian Fröhlich, Andrea Raimondi, Thomas A. Ryan, Massimiliano Stagi, Susanne A. Wycislo
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Disorders of lysosomal physiology have increasingly been found to underlie the pathology of a rapidly growing cast of neurodevelopmental disorders and sporadic diseases of aging. One cardinal aspect of lysosomal (dys)function is lysosomal acidificati
Autor:
Lorena Fernandez-Mosquera, Massimiliano Stagi, Ira Milosevic, Cátia V. Diogo, King Faisal Yambire, Nuno Raimundo, Amy H. Ponsford, Leonardo Pereyra, Kamil Pabis, Renata Couto
Publikováno v:
Autophagy
Mitochondria are key organelles for cellular metabolism, and regulate several processes including cell death and macroautophagy/autophagy. Here, we show that mitochondrial respiratory chain (RC) deficiency deactivates AMP-activated protein kinase (AM
Autor:
Amy H. Ponsford, James Boyd, Ulrich Stelzl, David J. MacEwan, Nicholas Harper, Christopher M. Sanderson, Erich E. Wanker, Jonathan Woodsmith, Jonathan Poh
Publikováno v:
Redox Biology, Vol 37, Iss, Pp 101686-(2020)
Redox Biology
Redox Biology
NRF2 (NFE2L2) is a cytoprotective transcription factor associated with >60 human diseases, adverse drug reactions and therapeutic resistance. To provide insight into the complex regulation of NRF2 responses, 1962 predicted NRF2-partner interactions w
Publikováno v:
Biochemical Society Transactions
In most tissues, cells are exposed to frequent changes in levels of oxidative stress and inflammation. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and nuclear factor-κB (NF-κB) are the two key transcription factors that regulate cellular res