Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Amy H, Herlihy"'
1
Akademický článek
Inflammation subsequent to mild iron excess differentially alters regional brain iron metabolism, oxidation and neuroinflammation status in mice
Autor: Azhaar Ahmad Ashraf, Manal Aljuhani, Chantal J. Hubens, Jérôme Jeandriens, Harold G. Parkes, Kalotina Geraki, Ayesha Mahmood, Amy H. Herlihy, Po-Wah So
Publikováno v: Frontiers in Aging Neuroscience, Vol 16 (2024)
Iron dyshomeostasis and neuroinflammation, characteristic features of the aged brain, and exacerbated in neurodegenerative disease, may induce oxidative stress-mediated neurodegeneration. In this study, the effects of potential priming with mild syst
Externí odkaz: https://doaj.org/article/32631ab5e47c408aa0a899ac30d736af
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2
Akademický článek
Repeatability and reproducibility of multiparametric magnetic resonance imaging of the liver.
Autor: Velicia Bachtiar, Matthew D Kelly, Henry R Wilman, Jaco Jacobs, Rexford Newbould, Catherine J Kelly, Michael L Gyngell, Katherine E Groves, Andy McKay, Amy H Herlihy, Carolina C Fernandes, Mark Halberstadt, Marion Maguire, Naomi Jayaratne, Sophia Linden, Stefan Neubauer, Rajarshi Banerjee
Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0214921 (2019)
As the burden of liver disease reaches epidemic levels, there is a high unmet medical need to develop robust, accurate and reproducible non-invasive methods to quantify liver tissue characteristics for use in clinical development and ultimately in cl
Externí odkaz: https://doaj.org/article/5859963dc92b4a2bbff5136ebcfff637
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3
Akademický článek
Non-invasive assessment of liver disease in rats using multiparametric magnetic resonance imaging: a feasibility study
Autor: Anna M. Hoy, Natasha McDonald, Ross J. Lennen, Matteo Milanesi, Amy H. Herlihy, Timothy J. Kendall, William Mungall, Michael Gyngell, Rajarshi Banerjee, Robert L. Janiczek, Philip S. Murphy, Maurits A. Jansen, Jonathan A. Fallowfield
Publikováno v: Biology Open, Vol 7, Iss 7 (2018)
Non-invasive quantitation of liver disease using multiparametric magnetic resonance imaging (MRI) could refine clinical care pathways, trial design and preclinical drug development. The aim of this study was to evaluate the use of multiparametric MRI
Externí odkaz: https://doaj.org/article/1b426a0f0e31422f831a288be36cea76
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4
Reference range of liver corrected T1 values in a population at low risk for fatty liver disease—a UK Biobank sub-study, with an appendix of interesting cases
Autor: Amirkasra Mojtahed, S. Kin, Stefan Neubauer, Mukesh G. Harisinghani, Henry R. Wilman, Jimmy D. Bell, Andrew McKay, Catherine Kelly, Matt Kelly, Rajarshi Banerjee, E L Thomas, Matteo Milanesi, Amy H. Herlihy
Publikováno v: Abdominal Radiology (New York)
Purpose Corrected T1 (cT1) value is a novel MRI-based quantitative metric for assessing a composite of liver inflammation and fibrosis. It has been shown to distinguish between non-alcoholic fatty liver disease (NAFL) and non-alcoholic steatohepatiti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4817d6631bfab404d76c1a32f187a43b
https://doi.org/10.1007/s00261-018-1701-2
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5
Multiparametric magnetic resonance imaging for quantitation of liver disease: a two-centre cross-sectional observational study
Autor: Scott Ian Kay Semple, Timothy J. Kendall, Natasha McDonald, Peter J Eddowes, Stefan G. Hubscher, Stella Kin, Rachel M. Brown, Desley Neil, James Hodson, Catherine Kelly, Nigel P. Davies, Miranda Phillips, Gideon M. Hirschfield, Amy H. Herlihy, Jonathan A. Fallowfield
Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
McDonald, N, Eddowes, P J, Hodson, J, Semple, S I K, Davies, N P, Kelly, C J, Kin, S, Phillips, M, Herlihy, A H, Kendall, T J, Brown, R M, Neil, D A H, Hübscher, S G, Hirschfield, G M & Fallowfield, J A 2018, ' Multiparametric magnetic resonance imaging for quantitation of liver disease : a two-centre cross-sectional observational study ', Scientific Reports, vol. 8, no. 1, pp. 9189 . https://doi.org/10.1038/s41598-018-27560-5
LiverMultiScan is an emerging diagnostic tool using multiparametric MRI to quantify liver disease. In a two-centre prospective validation study, 161 consecutive adult patients who had clinically-indicated liver biopsies underwent contemporaneous non-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0f5d6814ad7ca667601b3aedc79dca
http://link.springer.com/article/10.1038/s41598-018-27560-5
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6
Utility and cost evaluation of multiparametric magnetic resonance imaging for the assessment of non-alcoholic fatty liver disease
Autor: Stefan G. Hubscher, Catherine Kelly, P N Newsome, Natasha McDonald, Jonathan A. Fallowfield, Timothy J. Kendall, Simon Olliff, Matt Kelly, Robert Flintham, Rui V. Duarte, Scott Semple, Peter J Eddowes, Roman Wesolowski, James Hodson, Laurence Blake, Nigel P. Davies, Amy H. Herlihy, Gideon M. Hirschfield
Publikováno v: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Eddowes, P J, McDonald, N, Davies, N, Semple, S IK, Kendall, T J, Hodson, J, Newsome, P N, Flintham, R, Wesolowski, R, Blake, L, Duarte, R V, Kelly, C J, Herlihy, A H, Kelly, M D, Olliff, S P, Hubscher, S, Fallowfield, J A & Hirschfield, G M 2017, ' Utility and cost evaluation of multiparametric magnetic resonance imaging for the assessment of non-alcoholic fatty liver disease ', Alimentary Pharmacology and Therapeutics . https://doi.org/10.1111/apt.14469
Background: Validated diagnostic tools that are accurate, cost effective and acceptable to patients are required for disease stratification and monitoring in NAFLD. Aims: We investigated the performance and cost of multiparametric MRI alongside exist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5886a9743c09b55cfaa6f7d64915a409
https://doi.org/10.1111/apt.14469
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7
Repeatability and reproducibility of multiparametric magnetic resonance imaging of the liver
Autor: Jaco Jacobs, Marion Maguire, Michael L. Gyngell, Velicia Bachtiar, Mark Halberstadt, Rexford D. Newbould, Carolina Fernandes, Catherine Kelly, Katherine E. Groves, Henry R. Wilman, Naomi Jayaratne, Matt Kelly, Amy H. Herlihy, Rajarshi Banerjee, Andrew McKay, Stefan Neubauer, Sophia Linden
Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0214921 (2019)
As the burden of liver disease reaches epidemic levels, there is a high unmet medical need to develop robust, accurate and reproducible non-invasive methods to quantify liver tissue characteristics for use in clinical development and ultimately in cl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a034e2e5ac3673fb64f3f0b00759f5ea
https://doaj.org/article/5859963dc92b4a2bbff5136ebcfff637
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10
Characterisation of liver fat in the UK Biobank cohort
Autor: Paul M. Matthews, Michael L. Gyngell, Henry R. Wilman, E L Thomas, Steve Garratt, Jimmy D. Bell, Rajarshi Banerjee, Matteo Milanesi, Stefan Neubauer, Amy H. Herlihy, Matt Kelly
Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0172921 (2017)
Non-alcoholic fatty liver disease and the risk of progression to steatohepati tis, cirrhosis and hepatocellular carcinoma have been identified as major public health concerns. We have demonstrated the feasibility and potential value of measuring live
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394ef41a114041dff67d8488da6b8fb2
https://pubmed.ncbi.nlm.nih.gov/28445545
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