Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Amy Gillgrass"'
Autor:
Ana L. Portillo, Jonathan K. Monteiro, Eduardo A. Rojas, Tyrah M. Ritchie, Amy Gillgrass, Ali A. Ashkar
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The ability to expand and activate natural Killer (NK) cells ex vivo has dramatically changed the landscape in the development of novel adoptive cell therapies for treating cancer over the last decade. NK cells have become a key player for cancer imm
Externí odkaz:
https://doaj.org/article/237ae83ffc0449d2bf7110b7e8986060
Autor:
Sam Afkhami, Michael R. D’Agostino, Maryam Vaseghi-Shanjani, Madeleine Lepard, Jack X. Yang, Rocky Lai, Margaret Wa Yan Choi, Alexis Chacon, Anna Zganiacz, Kees L. M. C. Franken, Hildegund C. Ertl, Tom H. M. Ottenhoff, Mangalakumari Jeyanathan, Amy Gillgrass, Zhou Xing
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Viral-vectored vaccines are highly amenable for respiratory mucosal delivery as a means of inducing much-needed mucosal immunity at the point of pathogen entry. Unfortunately, current monovalent viral-vectored tuberculosis (TB) vaccine candi
Externí odkaz:
https://doaj.org/article/d2dc7116602d419c9248036c6fe44964
Autor:
Madeleine Lepard, Jack X. Yang, Sam Afkhami, Aisha Nazli, Anna Zganiacz, Shangguo Tang, Margaret Wa Yan Choi, Fatemah Vahedi, Alexandre Deshiere, Michel J. Tremblay, Zhou Xing, Charu Kaushic, Amy Gillgrass
Publikováno v:
Viruses, Vol 14, Iss 9, p 1927 (2022)
In people living with HIV, Mycobacterium tuberculosis (Mtb) is the major cause of death. Due to the increased morbidity/mortality in co-infection, further research is urgently required. A limiting factor to research in HIV and HIV/Mtb co-infection is
Externí odkaz:
https://doaj.org/article/5b98d467a3d942cca7b2d2b38ba2bc94
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Although antiretroviral therapy has transformed human immunodeficiency virus-type 1 (HIV-1) from a deadly infection into a chronic disease, it does not clear the viral reservoir, leaving HIV-1 as an uncurable infection. Currently, 1.2 million new HIV
Externí odkaz:
https://doaj.org/article/82f70016527d42389885769af147d618
Autor:
Sam Afkhami, Anne Drumond Villela, Michael R. D’Agostino, Mangalakumari Jeyanathan, Amy Gillgrass, Zhou Xing
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chemotherapeutic intervention remains the primary strategy in treating and controlling tuberculosis (TB). However, a complex interplay between therapeutic and patient-related factors leads to poor treatment adherence. This in turn continues to give r
Externí odkaz:
https://doaj.org/article/698aadb2c0e74fd79be7168ea44c90fd
Autor:
Mira M. Shenouda, Amy Gillgrass, Tina Nham, Richard Hogg, Amanda J. Lee, Marianne V. Chew, Mahsa Shafaei, Craig Aarts, Dean A. Lee, John Hassell, Anita Bane, Sukhbinder Dhesy-Thind, Ali A. Ashkar
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-14 (2017)
Abstract Background Natural killer (NK) cells play a critical role in cancer immunosurveillance. Recent developments in NK cell ex-vivo expansion makes it possible to generate millions of activated NK cells from a small volume of peripheral blood. We
Externí odkaz:
https://doaj.org/article/e54463b04cb049b2a8ca924521f7ce2a
Autor:
Nicole G Barra, Rengasamy Palanivel, Emmanuel Denou, Marianne V Chew, Amy Gillgrass, Tina D Walker, Josh Kong, Carl D Richards, Manel Jordana, Stephen M Collins, Bernardo L Trigatti, Alison C Holloway, Sandeep Raha, Gregory R Steinberg, Ali A Ashkar
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114799 (2014)
Interleukin-15 (IL-15) is an immunomodulatory cytokine that affects body mass regulation independent of lymphocytes; however, the underlying mechanism(s) involved remains unknown. In an effort to investigate these mechanisms, we performed metabolic c
Externí odkaz:
https://doaj.org/article/3b4ba187aaf348a0922604e1373b3f92
Autor:
Ali Zhang, Zhou Xing, Allyssa Phelps, Brian D. Lichty, Uma Sankar, Xiangqian Luo, Matthew S. Miller, Sam Afkhami, Gluke Ye, Mangalakumari Jeyanathan, Jegarubee Bavananthasivam, Ramandeep Singh, Yonghong Wan, Fiona Smaill, Hannah D. Stacey, Maria Fe C. Medina, Manel Jordana, Jann C. Ang, Karen L. Mossman, Natallia Kazhdan, Anna Zganiacz, Amy Gillgrass, Joshua F E Koenig, Fuan Wang, Art Marzok, Alisha Kang
SummaryThe emerging SARS-CoV-2 variants of concern (VOC) increasingly threaten the effectiveness of current first-generation COVID-19 vaccines that are administered intramuscularly and are designed to only target the spike protein. There is thus a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c690d9571ac96fca0f1520c7da5a05cc
https://doi.org/10.1101/2021.07.16.452721
https://doi.org/10.1101/2021.07.16.452721
Autor:
Sam Afkhami, Michael R. D’Agostino, Ali Zhang, Hannah D. Stacey, Art Marzok, Alisha Kang, Ramandeep Singh, Jegarubee Bavananthasivam, Gluke Ye, Xiangqian Luo, Fuan Wang, Jann C. Ang, Anna Zganiacz, Uma Sankar, Natallia Kazhdan, Joshua F.E. Koenig, Allyssa Phelps, Steven F. Gameiro, Shangguo Tang, Manel Jordana, Yonghong Wan, Karen L. Mossman, Mangalakumari Jeyanathan, Amy Gillgrass, Maria Fe C. Medina, Fiona Smaill, Brian D. Lichty, Matthew S. Miller, Zhou Xing
Publikováno v:
Cell. 185(5)
The emerging SARS-CoV-2 variants of concern (VOCs) threaten the effectiveness of current COVID-19 vaccines administered intramuscularly and designed to only target the spike protein. There is a pressing need to develop next-generation vaccine strateg
Autor:
Amy Gillgrass, Alisha Kang, Xiangqian Luo, Sam Afkhami, Mangalakumari Jeyanathan, Ramandeep Singh, Zhou Xing
Publikováno v:
The FASEB Journal
The COVID‐19 pandemic has unfolded to be the most challenging global health crisis in a century. In 11 months since its first emergence, according to WHO, the causative infectious agent SARS‐CoV‐2 has infected more than 100 million people and c