Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Amy F. Danson"'
Autor:
Francisco Rodriguez-Algarra, Robert A. E. Seaborne, Amy F. Danson, Selin Yildizoglu, Harunori Yoshikawa, Pui Pik Law, Zakaryya Ahmad, Victoria A. Maudsley, Ama Brew, Nadine Holmes, Mateus Ochôa, Alan Hodgkinson, Sarah J. Marzi, Madapura M. Pradeepa, Matthew Loose, Michelle L. Holland, Vardhman K. Rakyan
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Ribosomal DNA (rDNA) displays substantial inter-individual genetic variation in human and mouse. A systematic analysis of how this variation impacts epigenetic states and expression of the rDNA has thus far not been performed. Res
Externí odkaz:
https://doaj.org/article/23885abfca144e819fd856b19d936cdb
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-10 (2018)
Abstract Background Environmental influences fluctuate throughout the life course of an organism. It is therefore important to understand how the timing of exposure impacts molecular responses. Herein, we examine the responses of two key molecular ma
Externí odkaz:
https://doaj.org/article/8a3af5aa4e4d48f8bf4e940106f00c7e
Autor:
Robert Lowe, Selin Yildizoglu, Frédéric Saldmann, Mélanie Viltard, Chris G. Faulkes, Gérard Friedlander, Vardhman K. Rakyan, Amy F. Danson
Publikováno v:
Aging. 12:4394-4406
The naked mole-rat, Heterocephalus glaber (NMR), the longest-lived rodent, is of significance and interest in the study of biomarkers for ageing. Recent breakthroughs in this field have revealed 'epigenetic clocks' that are based on the temporal accu
Autor:
Nadine Holmes, Robert A. Seaborne, Madapura M Pradeepa, Sarah J. Marzi, Francisco Rodríguez-Algarra, Alan Hodgkinson, Amy F. Danson, Matthew Loose, Victoria A Maudsley, Vardhman K. Rakyan, Pui Pik Law, Ama Brew, Zakaryya Ahmad, Harunori Yoshikawa, Michelle L. Holland, Selin Yildizoglu
Publikováno v:
Genome biology. 23(1)
Background Ribosomal DNA (rDNA) displays substantial inter-individual genetic variation in human and mouse. A systematic analysis of how this variation impacts epigenetic states and expression of the rDNA has thus far not been performed. Results Usin
Publikováno v:
Human reproduction update. 26(6)
BACKGROUND Studies in non-human mammals suggest that environmental factors can influence spermatozoal DNA methylation, and some research suggests that spermatozoal DNA methylation is also implicated in conditions such as subfertility and imprinting d
Autor:
Robert, Lowe, Amy F, Danson, Vardhman K, Rakyan, Selin, Yildizoglu, Frédéric, Saldmann, Melanie, Viltard, Gérard, Friedlander, Chris G, Faulkes
Publikováno v:
Aging (Albany NY)
The naked mole-rat, Heterocephalus glaber (NMR), the longest-lived rodent, is of significance and interest in the study of biomarkers for ageing. Recent breakthroughs in this field have revealed ‘epigenetic clocks’ that are based on the temporal
Autor:
Michelle L. Holland, Robert Lowe, Elena Loche, Guillermo Carbajosa, Susan E. Ozanne, Vardhman K. Rakyan, Paul W. Caton, Carolina Gemma, Amy F. Danson, Asha A. M. Carpenter
Publikováno v:
Holland, M L, Lowe, R, Caton, P W, Gemma, C, Carbajosa, G, Danson, A F, Carpenter, A M, Loche, E, Ozanne, S E & Rakyan, V K 2016, ' Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice ', Science, vol. 353, no. 6298, pp. 495-498 . https://doi.org/10.1126/science.aaf7040
Mom's diet affects growth Nutrition is important during development. This appears to be true even in utero, with potential long-lasting effects on adult phenotype and disease. Epigenetic factors are prime suspects in identifying the corresponding mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51503f16ec29a114b9c31e13fa4ad29
https://www.repository.cam.ac.uk/handle/1810/256987
https://www.repository.cam.ac.uk/handle/1810/256987