Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Amy Ewald"'
Autor:
Rui Wang, David A Eichenbaum, Namrata Saroj, Carl Regillo, Charles Clifton Wykoff, Cynthia K McClard, Victoria Windham, Sagit Fried, Erik B Lehman, Mirataollah Salabati, Raziyeh Mahmoudzadeh, Stephen Laswell, Michael Ammar, Jordyn Vannavong, Aamir A Aziz, Amy Ewald, Allison V Calvanese, Adriana Strutt, Arshad Mohammad Khanani
Publikováno v:
BMJ Open Ophthalmology, Vol 7, Iss 1 (2022)
Aim To quantify the areas of burden experienced by patients requiring repeated intravitreal injections (IVI) in the management of exudative retinal diseases.Methods The validated Questionnaire to Assess Life Impact of Treatment by Intravitreal Inject
Externí odkaz:
https://doaj.org/article/8dd90cb4264943abba0e5742c622fb13
Autor:
Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E. Williamson, Bryan D. McElroy, Eduardo R. Butelman, Thomas E. Prisinzano, Bronwyn M. Kivell
Publikováno v:
Molecules, Vol 28, Iss 12, p 4848 (2023)
Kappa opioid receptor (KOR) agonists have preclinical antipsychostimulant effects; however, adverse side effects have limited their therapeutic development. In this preclinical study, conducted in Sprague Dawley rats, B6-SJL mice, and non-human prima
Externí odkaz:
https://doaj.org/article/54b17a5470e048c9ae4d03998c440fe7
Autor:
Kivell, Ross van de Wetering, Amy Ewald, Susan Welsh, Lindsay Kornberger, Samuel E. Williamson, Bryan D. McElroy, Eduardo R. Butelman, Thomas E. Prisinzano, Bronwyn M.
Publikováno v:
Molecules; Volume 28; Issue 12; Pages: 4848
Kappa opioid receptor (KOR) agonists have preclinical antipsychostimulant effects; however, adverse side effects have limited their therapeutic development. In this preclinical study, conducted in Sprague Dawley rats, B6-SJL mice, and non-human prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::116958beed00da1b01278045adb2c4b5
Autor:
Denise S. Simpson, N. Kumar, L. Walker, Aashish S. Morani, B. Simonson, Thomas E. Prisinzano, John H. Miller, Bronwyn M. Kivell, Amy Ewald
Publikováno v:
British Journal of Pharmacology. 172:515-531
Background and Purpose Acute activation of κ opioid (KOP) receptors results in anticocaine-like effects, but adverse effects, such as dysphoria, aversion, sedation and depression, limit their clinical development. Salvinorin A, isolated from the pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6834ffed26c58bef3724927e81f12834
https://doi.org/10.1111/bph.12692
https://doi.org/10.1111/bph.12692
Autor:
Amy Ewald, Katherine M. Prevatt-Smith, Thomas E. Prisinzano, Aashish S. Morani, Bronwyn M. Kivell
Publikováno v:
European Journal of Pharmacology. 720:69-76
κ opioid receptor activation by traditional arylacetamide agonists and the novel neoclerodane diterpene κ opioid receptor agonist Salvinorin A (Sal A) results in attenuation of cocaine-seeking behavior in pre-clinical models of addiction. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f744be00a3890ff9068f849a7ffdf291
https://doi.org/10.1016/j.ejphar.2013.10.050
https://doi.org/10.1016/j.ejphar.2013.10.050
Autor:
Peter J. Bosch, Rachel Saylor Crowley, Aimee Culverhouse, Benjamin Neuenswander, Bronwyn M. Kivell, Amy Ewald, Thomas E. Prisinzano
Publikováno v:
Psychopharmacology. 234(16)
Kappa-opioid receptor (KOPr) agonists have pre-clinical anti-cocaine and analgesic effects. However, side effects including sedation, dysphoria, aversion, anxiety and depression limit their therapeutic development. The unique structure of salvinorin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5c7d5439dc97489d3f050b28a6ef71
https://pubmed.ncbi.nlm.nih.gov/28536865
https://pubmed.ncbi.nlm.nih.gov/28536865
Autor:
Bridget Simonson, Elizabeth A. Bolan, Lakshmi A. Devi, Bronwyn M. Kivell, Zeljko Uzelac, Santhanalakshmi Sundaramurthy, Amy Ewald, Balasubramaniam Annamalai, Jeyaganesh Rajamanickam, Toni S. Shippenberg, Thomas E. Prisinzano, Padmanabhan Mannangatti, Harald H. Sitte, Lankupalle D. Jayanthi, Sammanda Ramamoorthy, Vanaja Jaligam, Ivone Gomes, Vladimir I. Chefer
Publikováno v:
Neuropharmacology. 86
Salvinorin A (SalA), a selective κ-opioid receptor (KOR) agonist, produces dysphoria and pro-depressant like effects. These actions have been attributed to inhibition of striatal dopamine release. The dopamine transporter (DAT) regulates dopamine tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319249dc8e233f1c080b76b7d0f25e2a
https://pubmed.ncbi.nlm.nih.gov/25107591
https://pubmed.ncbi.nlm.nih.gov/25107591
Acute activation of kappa-opioid receptors produces anti-addictive effects by regulating dopamine levels in the brain. Unfortunately, classic kappa-opioid agonists have undesired side effects such as sedation, aversion, and depression, which restrict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77527dbabd105bb54fa21838198af1f
https://doi.org/10.1016/b978-0-12-420118-7.00012-3
https://doi.org/10.1016/b978-0-12-420118-7.00012-3
Publikováno v:
Drug and Alcohol Dependence. 156:e65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e95d92407fd7531ae0e879ce08589be
https://doi.org/10.1016/j.drugalcdep.2015.07.1095
https://doi.org/10.1016/j.drugalcdep.2015.07.1095
Publikováno v:
Frontiers in Neurology, Vol 2 (2011)
The Optic Neuritis Treatment Trial and subsequent studies have had a tremendous impact on the treatment and prognosis of optic neuritis and multiple sclerosis in adults. The results of these studies have been extrapolated to children; however, pediat
Externí odkaz:
https://doaj.org/article/430bbcf31f87458283479a6058f0ad65