Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Amy E. Hanlon Newell"'
Autor:
Jessie T. Yan, Yue Jin, Ernest Lo, Yilin Chen, Amy E. Hanlon Newell, Ying Kong, Landon J. Inge
Publikováno v:
Oncology and Therapy, Vol 11, Iss 3, Pp 343-360 (2023)
Abstract Introduction Biomarker testing is increasingly crucial for patients with early-stage non-small cell lung cancer (eNSCLC). We explored biomarker test utilization and subsequent treatment in eNSCLC patients in the real-world setting. Methods U
Externí odkaz:
https://doaj.org/article/440344a2adf541a58418c583ecbf44ab
Autor:
Rui Henrique, Paula Lopes, Isaac Bai, Espen Walker, João Lobo, Andréia Cruz, Amy E. Hanlon Newell, Luís Antunes, Julia Coach, Sara Petronilho, Greg Harlow
Publikováno v:
Modern Pathology. 32:1574-1586
Breast cancer is a heterogeneous disease and additional biomarkers for individually predicting patient outcomes are needed. Aberrant membrane E-cadherin immunoexpression has been demonstrated in lobular breast cancer. Also, E-cadherin nuclear stainin
Autor:
Amy E. Hanlon Newell, Greg Harlow, Patrizia Dell'Orto, Leila Russo, Espen Walker, Patrick Maisonneuve, Giuseppe Viale, Isaac Bai
Publikováno v:
Breast Cancer Research and Treatment
Introduction Ki-67 labeling index assessed by immunohistochemical assays has been shown useful in assessing the risk of recurrence for estrogen receptor (ER)-positive HER2-negative breast cancers (BC) and distinguishing Luminal A-like from Luminal B-
Autor:
Richard S P Huang, Raji V Marati, Deepa Dalvi, Brittany Admire, Amy E. Hanlon Newell, Courtney Powell, B. Holmes, Ashley Streator, Ehab Elgabry, Javier Perez, Dusty Tyree
Publikováno v:
Archives of pathologylaboratory medicine. 143(11)
Context.— Delta-like protein 3 (DLL3) is a protein that is implicated in the Notch pathway. Objective.— To present data on DLL3 prevalence in small cell lung cancer and staining characteristics of the VENTANA DLL3 (SP347) Assay. In addition, the
Autor:
Christopher Lanigan, Karen C. Mrazeck, Espen Walker, Brian Mosteller, Daniel Warren, J. Jordi Rowe, Raymond Jones, Amy E. Hanlon Newell, Benjamin C. Calhoun, Margie H Smith
Publikováno v:
Annals of diagnostic pathology. 35
Objective Comparison of analytical and immunohistochemical performance of progesterone receptor (PR) antibodies with correlation to recurrence of invasive breast cancer treated with endocrine therapy. Methods The binding-affinity kinetics of PR clone
Autor:
Andreas Rosenwald, Manfred Gessler, Amy E. Hanlon Newell, Claus Steinlein, Lev M. Fedorov, Susan B. Olson, Qi Tian, Michael Schmid, Burkhard Kneitz
Publikováno v:
Chromosome Research. 22:375-392
Chromosome aberrations (aneuploidies mostly) are the cause of the majority of spontaneous abortions in humans. However, little is known about defects in the underlying molecular mechanisms resulting in chromosome aberrations and following failure of
Autor:
Robb E. Moses, Susan B. Olson, Navid Ziaie, Scott Rennie, Nichole Owen, Amy E. Hanlon Newell, Asia D. Mitchell, James Hejna
Publikováno v:
Cytogenetic and Genome Research. 144:255-263
Biallelic mutations in BLM cause Bloom syndrome (BS), a genome instability disorder characterized by growth retardation, sun sensitivity and a predisposition to cancer. As evidence of decreased genome stability, BS cells demonstrate not only elevated
Autor:
Milton J. Finegold, Markus Grompe, Susan B. Olson, Amy E. Hanlon Newell, Weimin Bi, Arthur L. Beaudet, Andrew W. Duncan
Publikováno v:
Journal of Clinical Investigation. 122:3307-3315
Over half of the mature hepatocytes in mice and humans are aneuploid and yet retain full ability to undergo mitosis. This observation has raised the question of whether this unusual somatic genetic variation evolved as an adaptive mechanism in respon
Autor:
Amy E. Hanlon Newell, Jane E. Yates, Susan B. Olson, Stefanie Kaech, Kim Hien T. Dao, Grover C. Bagby, Brian J. Druker, Curtis L. Petersen, Whitney D. Nelson, Michael D. Rotelli
Publikováno v:
Blood. 120:323-334
Bone marrow failure is a nearly universal complication of Fanconi anemia. The proteins encoded by FANC genes are involved in DNA damage responses through the formation of a multisubunit nuclear complex that facilitates the E3 ubiquitin ligase activit
Autor:
Nathaniel Jillette, Kathy Chin, R. Keaney Rathbun, Muhsen Al-Dhalimy, Anupriya Agarwal, Laura E. Hays, Michael R. Garbati, Grover C. Bagby, Amy E. Hanlon Newell, Susan B. Olson
The Fanconi anemia proteins participate in a canonical pathway that repairs cross-linking agent-induced DNA damage. Cells with inactivated Fanconi anemia genes are universally hypersensitive to such agents. Fanconi anemia-deficient hematopoietic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf6d5b8ff88b3afe1ef9118a91b0fcd
https://europepmc.org/articles/PMC6608044/
https://europepmc.org/articles/PMC6608044/