Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Amy E. Brix"'
Publikováno v:
Toxicologic Pathology. 49:1062-1076
Oral cancer is the seventh most common malignancy worldwide, and lifestyle factors participate in its development. Rodent studies can help identify substances that contribute to its development and provide information on the early stages of carcinoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e49b314e77f343d56ab83295b7dd48f
https://doi.org/10.1177/0192623321989956
https://doi.org/10.1177/0192623321989956
Autor:
Sukhdev S. Brar, June K. Dunnick, Kevin Gerrish, Ralph E. Wilson, Esra Mutlu, Daniel L. Morgan, Arun R. Pandiri, Keith R. Shockley, Thai-Vu T. Ton, Amy E. Brix, Gregory S. Travlos, Suramya Waidyanatha
Publikováno v:
Toxicol Pathol
Human exposure to pentabromodiphenyl ether (PBDE) mixture (DE-71) and its PBDE-47 congener can occur both in utero and during lactation. Here we tested the hypothesis that PBDE-induced neonatal hepatic transcriptomic alterations in Wistar Han rat pup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7274290d78d5871c374abae57d3356a
https://doi.org/10.1177/0192623319888433
https://doi.org/10.1177/0192623319888433
Publikováno v:
Toxicol Pathol
The National Toxicology Program (NTP) uses histopathological evaluation of animal tissues as a key element in its toxicity and carcinogenicity studies. The initial histopathological evaluations are subjected to a rigorous peer review process involvin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014db8d63389ff509d49227ef2f7bab7
https://doi.org/10.1177/0192623319873974
https://doi.org/10.1177/0192623319873974
Autor:
Timonthy Maynor, June K. Dunnick, Leslie Rescio, Suramya Waidyanatha, Thai-Vu T. Ton, Grace E. Kissling, Helen Cunny, Siuzanne L. Phillips, Hue-Hua L. Hong, Esra Mutlu, Michael J. DeVito, Amy E. Brix, Robert C. Sills, Bruce Alex Merrick, Arun R. Pandiri
Publikováno v:
Data in Brief
Data in Brief, Vol 21, Iss, Pp 2125-2128 (2018)
Data in Brief, Vol 21, Iss, Pp 2125-2128 (2018)
This article describes data related to the research article entitled “Carcinogenic activity of pentabrominated diphenyl ether mixture (DE-71) in rats and mice” (Dunnick et al., 2018). PBDE-induced hepatocellular tumors harbored Hras and Ctnnb1 mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d06201b9ecd22cde41a7ad3d23fa7b5
https://doi.org/10.1016/j.dib.2018.10.104
https://doi.org/10.1016/j.dib.2018.10.104
Autor:
Bruce Alex Merrick, Grace E. Kissling, Esra Mutlu, Amy E. Brix, Arun R. Pandiri, T. V. Ton, Helen Cunny, Suramya Waidyanatha, Hue-Hua L. Hong, Michael J. DeVito, Leslie Recio, Suzanne L. Phillips, Timothy Maynor, Robert C. Sills, June K. Dunnick
Publikováno v:
Toxicology Reports, Vol 5, Iss, Pp 615-624 (2018)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Pentabrominated diphenyl ether (PBDE) mixture was a multispecies carcinogen causing liver tumors in male and female rats and mice. • Hras or Ctnnb1 mutations characterized the PBDE-induced liver tumors. • PB
Highlights • Pentabrominated diphenyl ether (PBDE) mixture was a multispecies carcinogen causing liver tumors in male and female rats and mice. • Hras or Ctnnb1 mutations characterized the PBDE-induced liver tumors. • PB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266f307cb8f0fdcb8710fda714a500b8
https://doi.org/10.1016/j.toxrep.2018.05.010
https://doi.org/10.1016/j.toxrep.2018.05.010
Autor:
Yu Wang, Kevin Gerrish, Amy E. Brix, Gordon P. Flake, Daniel L. Morgan, Keith R. Shockley, June K. Dunnick, B. Alex Merrick, Julie F. Foley
Publikováno v:
Toxicologic Pathology. 44:835-847
N, N-dimethyl-p-toluidine (DMPT; Cas No. 99-97-8), an accelerant for methyl methacrylate monomers in medical devices, is a nasal cavity carcinogen according to a 2-yr cancer study of male and female F344/N rats, with the nasal tumors arising from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701c5810a4f5d162665bb1a42001a1a1
https://doi.org/10.1177/0192623316637708
https://doi.org/10.1177/0192623316637708
Autor:
Grace E. Kissling, Kristen Ryan, Mark F. Cesta, Daniel L. Morgan, Michelle C. Cora, Amy E. Brix, Ronald A. Herbert, Kristine L. Witt
Publikováno v:
Toxicology and Industrial Health. 33:385-405
Metalworking fluids (MWFs) are complex formulations designed for effective lubricating, cooling, and cleaning tools and parts during machining operations. Adverse health effects such as respiratory symptoms, dermatitis, and cancer have been reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167f2e62b0d662bf36c10e9c34d351ce
https://doi.org/10.1177/0748233716653912
https://doi.org/10.1177/0748233716653912
Autor:
Guozhu Zhang, Ralph E. Wilson, Richard Gilliam, G. Jean Harry, Christopher A. McPherson, Sukhdev S. Brar, Amy E. Brix, Catherine A. Picut
Publikováno v:
Neurotoxicity Research
At elevated levels, fluoride (F−) exposure has been associated with adverse human health effects. In rodents, F− exposure has been reported to induce deficits in motor performance and learning and memory. In this study, we examined Long-Evans hoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf31669d8fe02eb41ed7b96c2c13947
https://pubmed.ncbi.nlm.nih.gov/29404855
https://pubmed.ncbi.nlm.nih.gov/29404855
Autor:
Mark F. Cesta, Linda S. Birnbaum, Emily Singletary, Ronald A. Herbert, John R. Bucher, David E. Malarkey, Amy E. Brix, Robert C. Sills, Melvin H. Hamlin
Publikováno v:
Toxicologic Pathology. 42:458-460
Toxicologists and pathologists worldwide will benefit from a new, website-based, and completely searchable Nonneoplastic Lesion Atlas just released by the U.S. National Toxicology Program (NTP). The atlas is a much-needed resource with thousands of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdc2d931d459a3e13c48316332d6d40
https://doi.org/10.1177/0192623313517304
https://doi.org/10.1177/0192623313517304
Autor:
Abraham Nyska, Takanori Harada, David E. Malarkey, Dai Nakae, Bhanu Singh, Michael P. Vinlove, Colin G. Rousseaux, Richard Gregson, Jerrold M. Ward, Thomas Nolte, Fiorella Belpoggi, Bob Thoolen, Wolfgang Kaufmann, Amy E. Brix, Ulrich Deschl, Robert R. Maronpot, Karin Küttler
Publikováno v:
Toxicologic Pathology. 38:5S-81S
The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North Ame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075f7bf6475341eb0f08378605631638
https://doi.org/10.1177/0192623310386499
https://doi.org/10.1177/0192623310386499