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of 5
pro vyhledávání: '"Amy E Tucker"'
Autor:
David C Whitacre, Diego A Espinosa, Cory J Peters, Joyce E Jones, Amy E Tucker, Darrell L Peterson, Fidel P Zavala, David R Milich
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124856 (2015)
In order to design P. falciparum preerythrocytic vaccine candidates, a library of circumsporozoite (CS) T and B cell epitopes displayed on the woodchuck hepatitis virus core antigen (WHcAg) VLP platform was produced. To test the protective efficacy o
Externí odkaz:
https://doaj.org/article/25cb1a6c7c5a458393e2df575523d2d4
Autor:
Jimmy D. Ballard, Amy E. Tucker, Han Wang, William Ortiz-Leduc, Daniel E. Voth, Igor Dozmorov, Isabelle I. Salles, Michael Centola
Publikováno v:
Cellular Microbiology. 5:523-532
Summary The lethal factor (LF) component of Bacillus anthra- cis lethal toxin (LeTx) cleaves mitogen activated pro- tein kinase kinases (MAPKKs) in a variety of different cell types, yet only macrophages are rap- idly killed by this toxin. The reason
Autor:
Joyce E. Jones, Byung O. Lee, David R. Milich, David C. Whitacre, Lars Frelin, Bryan Darsow, Janice Hughes, Darrell L. Peterson, Matti Sällberg, Amy E. Tucker, Cory J. Peters
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(11)
Previous studies demonstrated that the primary APCs for the hepatitis B core Ag (HBcAg) were B cells and not dendritic cells (DC). We now report that splenic B1a and B1b cells more efficiently present soluble HBcAg to naive CD4+ T cells than splenic
Autor:
David C. Whitacre, Jean-Noel Billaud, Therese Wahlström, Lars Frelin, Amy E. Tucker, Byung O. Lee, Joyce E. Jones, David R. Milich, Darrell L. Peterson, Janice Hughes, Cory J. Peters
Publikováno v:
Journal of virology. 83(3)
Hepatitis B virus (HBV) expresses two structural forms of the nucleoprotein, the intracellular nucleocapsid (hepatitis core antigen [HBcAg]) and the secreted nonparticulate form (hepatitis e antigen [HBeAg]). The aim of this study was to evaluate the
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(21)
In the current study, we show that macrophages adaptively resist anthrax lethal toxin (LT) through a toxin-activated process termed toxin-induced resistance (TIR). TIR was triggered by pretreatment of RAW 264.7 or J774A.1 macrophages with a low dose