Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Amy E Sigmund"'
Autor:
Matthew A. Plummer, Robert DiCosimo, Amy E. Sigmund, Alison M. Walls, Arie Ben-Bassat, William L. Spillan
Publikováno v:
Advanced Synthesis & Catalysis. 350:1761-1769
A chemoenzymatic process has been developed that employs an immobilized microbial nitrilase biocatalyst for the conversion of glycolonitrile to high-purity glycolic acid. The specific activity of this immobilized cell biocatalyst decreased significan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cdae3d391c43deacba62acd1a85e136
https://doi.org/10.1002/adsc.200800228
https://doi.org/10.1002/adsc.200800228
Autor:
Amy E. Sigmund, Frederick B. Cooling, Mark S. Payne, Michael G. Bramucci, Susan K. Fager, John E. Gavagan, Robert DiCosimo, Eugenia C. Hann, Sarita Chauhan
Publikováno v:
Tetrahedron. 60:577-581
Acidovorax facilis 72W nitrilase catalyzed the regioselective hydrolysis of (E,Z)-2-methyl-2-butenenitrile, producing only (E)-2-methyl-2-butenoic acid with no detectable conversion of (Z)-2-methyl-2-butenenitrile. (E)-2-Methyl-2-butenoic acid, produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52993c31ca8917c7801da1989d582e40
https://doi.org/10.1016/j.tet.2003.10.120
https://doi.org/10.1016/j.tet.2003.10.120
Autor:
Frederick B. Cooling, Amy E. Sigmund, Arie Ben-Bassat, John E. Gavagan, Eugenia C. Hann, Sarita Chauhan, Susan K. Fager, Robert DiCosimo, Mark S. Payne, Susan Marie Hennessey
Publikováno v:
Advanced Synthesis & Catalysis. 345:775-782
Microbial catalysts having a combination of nitrile hydratase and amidase activities had a significantly-higher specific activity for hydrolysis of 3-hydroxyalkanenitriles than microbial nitrilase catalysts. Comamonas testosteroni 22–1, Dietzia sp.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bfce68fdfcdf8f4bf35a748a680a157
https://doi.org/10.1002/adsc.200303007
https://doi.org/10.1002/adsc.200303007
Autor:
Amy E Sigmund, Kenneth C McNulty, Dzuy Nguyen, Charlotte E Silverman, Philip Ma, Jaan A Pesti, Robert DiCosimo
Publikováno v:
Canadian Journal of Chemistry. 80:608-612
The present invention relates to a process for the enantioselective enzymatic aminolysis of racemic 2-[3-(4-cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetate ((R/S)-I) by methyl Nα-Boc-L-α,β-diaminoproprionate.p-toluenesulfonic acid. More specifically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6c959ee4f379b20a2e039f3c2325afc
https://doi.org/10.1139/v02-004
https://doi.org/10.1139/v02-004
Autor:
Sarita Chauhan, David R. Short, Eugenia Costa Hann, Susan Marie Hennessey, John E. Gavagan, Robert DiCosimo, Amy E. Sigmund, Arie Ben-Bassat, Mark S. Payne, Robert D. Fallon
Publikováno v:
Organic Process Research & Development. 6:492-496
Optimization of microbial cell immobilization, catalyst specific activity, and volumetric productivity were required for scale-up of the nitrilase-catalyzed hydrolysis of 2-methylglutaronitrile to ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9405fa1a3949b58e7ce4cd4f3116a4e2
https://doi.org/10.1021/op025515k
https://doi.org/10.1021/op025515k
Publikováno v:
Advanced Synthesis & Catalysis. 343:587-590
Candida antarctica lipase fraction B (CALB) catalyzed the hydrolysis of the (S)-enantiomer of racemic 4-oxo-1,2-pyrrolidinedicarboxylic acid dimethyl ester with high enantioselectivity (> 99.5% ee at 51% conversion). Regioselective hydrogenation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d83bdd550ff533114c24a44d04f492c3
https://doi.org/10.1002/1615-4169(200108)343:6/7<587::aid-adsc587>3.0.co
https://doi.org/10.1002/1615-4169(200108)343:6/7<587::aid-adsc587>3.0.co
Autor:
Amy E. Sigmund, Robert DiCosimo
Publikováno v:
Tetrahedron: Asymmetry. 15:2797-2799
The enantioselectivity of the lipase-catalyzed acetylation of several ( RS )-2-(1-aminoethyl)-3-chloro-5-(substituted)pyridines has been examined. An enantiomeric excess (substrate) of 94% at 55% conversion was obtained for acetylation of the ( R )-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c60012238234413327cb8174dcad5b06
https://doi.org/10.1016/j.tetasy.2004.07.043
https://doi.org/10.1016/j.tetasy.2004.07.043
Publikováno v:
ChemInform. 32
Candida antarctica lipase fraction B (CALB) catalyzed the hydrolysis of the (S)-enantiomer of racemic 4-oxo-1,2-pyrrolidinedicarboxylic acid dimethyl ester with high enantioselectivity (> 99.5% ee at 51% conversion). Regioselective hydrogenation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7257632da05bef64ff1b2bbe63c80107
https://doi.org/10.1002/chin.200150186
https://doi.org/10.1002/chin.200150186
Autor:
Eugenia C. Hann, Amy E. Sigmund, Susan K. Fager, Frederick B. Cooling, John E. Gavagan, Arie Ben-Bassat, Sarita Chauhan, Mark S. Payne, Susan M. Hennessey, Robert DiCosimo
Publikováno v:
Advanced Synthesis & Catalysis; Jun2003, Vol. 345 Issue 6/7, p775, 8p
Publikováno v:
Canadian Journal of Chemistry. Dec2002, Vol. 80 Issue 12, pC-1-C-12. 12p.