Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Amy E, Riek"'
Autor:
Jisu Oh, Amy E. Riek, Kevin T. Bauerle, Adriana Dusso, Kyle P. McNerney, Ruteja A. Barve, Isra Darwech, Jennifer E. Sprague, Clare Moynihan, Rong M. Zhang, Greta Kutz, Ting Wang, Xiaoyun Xing, Daofeng Li, Marguerite Mrad, Nicholas M. Wigge, Esmeralda Castelblanco, Alejandro Collin, Monika Bambouskova, Richard D. Head, Mark S. Sands, Carlos Bernal-Mizrachi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Environmental factors may alter the fetal genome to cause metabolic diseases. It is unknown whether embryonic immune cell programming impacts the risk of type 2 diabetes in later life. We demonstrate that transplantation of fetal hematopoiet
Externí odkaz:
https://doaj.org/article/006bb5f74e894a5ca7b478ca55888534
Autor:
Jisu Oh, Amy E. Riek, Isra Darwech, Katsuhiko Funai, JianSu Shao, Kathleen Chin, Oscar L. Sierra, Geert Carmeliet, Richard E. Ostlund Jr., Carlos Bernal-Mizrachi
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1872-1886 (2015)
Intense effort has been devoted to understanding predisposition to chronic systemic inflammation because it contributes to cardiometabolic disease. We demonstrate that deletion of the macrophage vitamin D receptor (VDR) in mice (KODMAC) is sufficient
Externí odkaz:
https://doaj.org/article/bc5131ee1f884f2a8768b841a92cbe05
Autor:
Jisu Oh, Amy E. Riek, Kevin T. Bauerle, Adriana Dusso, Kyle P. McNerney, Ruteja A. Barve, Isra Darwech, Jennifer Sprague, Clare Moynihan, Rong M Zhang, Ting Wang, Xiaoyun Xing, Daofeng Li, Richard D. Head, Monika Bambouskova, Marguerite Mrad, Alejandro Collins, Mark S. Sands, Carlos Bernal-Mizrachi
Environmental factors may alter the fetal genome to cause metabolic diseases. It is unknown whether embryonic immune cell programming impacts the risk of type 2 diabetes in later life. We demonstrate that transplantation of fetal hematopoietic stem c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c37639e53868c652b29c0eceabbc834
https://doi.org/10.1101/2022.09.08.507174
https://doi.org/10.1101/2022.09.08.507174
Autor:
Sherry Weng, Jennifer E Sprague, Jisu Oh, Amy E Riek, Kathleen Chin, Miguel Garcia, Carlos Bernal-Mizrachi
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54625 (2013)
Multiple epidemiological studies link vitamin D deficiency to increased cardiovascular disease (CVD), but causality and possible mechanisms underlying these associations are not established. To clarify the role of vitamin D-deficiency in CVD in vivo,
Externí odkaz:
https://doaj.org/article/d3765db41f1644918661d03456cd81f4
Autor:
Maria Luisa S. Sequeira-Lopez, Á Baldán, Jian Su Shao, R. A. Barve, Scot J. Matkovich, Robert P. Mecham, Mark S. Sands, Colin G. Nichols, R. A. Gomez, Hao Zhang, Russell H. Knutsen, Bruno A. Benitez, Amy E. Riek, S. M. Bindom, Kendall J. Blumer, Richard D. Head, Jisu Oh, Patrick Osei-Owusu, Carlos Bernal-Mizrachi, Geert Carmeliet
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Myeloid cells are known mediators of hypertension, but their role in initiating renin-induced hypertension has not been studied. Vitamin D deficiency causes pro-inflammatory macrophage infiltration in metabolic tissues and is linked to renin-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1176bdb10f2b0a5f6f3ff9a88a1e2ac1
https://lirias.kuleuven.be/handle/123456789/661748
https://lirias.kuleuven.be/handle/123456789/661748
Publikováno v:
Acta Physiol (Oxf)
Hypertension is the primary cause of cardiovascular mortality. Despite multiple existing treatments, only half of those with the disease achieve adequate control. Therefore, understanding the mechanisms causing hypertension is essential for the devel
Autor:
Xiaobo Lin, Jisu Oh, Amy E. Riek, Richard E. Ostlund, Veronica Worthy, Rong M. Zhang, Isra Darwech, Carlos Bernal-Mizrachi
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 177:187-192
Cross-sectional studies indicate consistent associations between low 25(OH)D concentration and increased risk of cardiovascular disease (CVD), but results of randomized control trials (RCTs) are mixed. However, the majority of the RCTs do not focus o
Autor:
Jisu Oh, Amy E. Riek, Adriana Dusso, Anabel L. Castro-Grattoni, R. Ariel Gomez, Maria Luisa S. Sequeira-Lopez, Carlos Bernal-Mizrachi, Kevin Thomas Bauerle
Publikováno v:
Journal of the Endocrine Society
Chronic inflammation and local activation of the renin-angiotensin-aldosterone system (RAAS) play a pivotal role in the pathogenesis and progression of diabetic complications. In patients with type 2 diabetes (T2DM), the prevalence of vitamin D defic
Publikováno v:
Journal of the Endocrine Society
Background: Vitamin D deficiency is prevalent in pregnant women and their offspring. Maternal vitamin D deficiency is associated with insulin resistance in children and can induce a proinflammatory macrophage phenotype [1, 2]. Purpose: We hypothesize
Autor:
Jisu Oh, Pamela Stone, Adriana Dusso, Rong Mei Zhang, Carlos Bernal-Mizrachi, Amy E. Riek, Ana Maria Arbelaez, Anabel L. Castro-Grattoni, Kevin Thomas Bauerle, Monika Bambouskova
Publikováno v:
Journal of the Endocrine Society
Introduction: Poor glycemic control is considered an important contributor to cardiovascular disease in patients with diabetes. Episodic hyperglycemia as a surrogate for glycemic variability promotes monocyte adhesion and increases the prevalence of