Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Amy E, Rabideau"'
Autor:
Athanasios Dousis, Kanchana Ravichandran, Elissa M. Hobert, Melissa J. Moore, Amy E. Rabideau
Publikováno v:
Nature Biotechnology. 41:560-568
In vitro transcription (IVT) is a DNA-templated process for synthesizing long RNA transcripts, including messenger RNA (mRNA). For many research and commercial applications, IVT of mRNA is typically performed using bacteriophage T7 RNA polymerase (T7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b22ad98c98f2659d824766b8781c8467
https://doi.org/10.1038/s41587-022-01525-6
https://doi.org/10.1038/s41587-022-01525-6
Autor:
Amy E. Rabideau, Bradley L. Pentelute
Publikováno v:
ACS Central Science, Vol 1, Iss 8, Pp 423-430 (2015)
Externí odkaz:
https://doaj.org/article/e5f9b56c89774e2faa1158faad1feab6
Autor:
Athanasios, Dousis, Kanchana, Ravichandran, Elissa M, Hobert, Melissa J, Moore, Amy E, Rabideau
Publikováno v:
Nature biotechnology.
In vitro transcription (IVT) is a DNA-templated process for synthesizing long RNA transcripts, including messenger RNA (mRNA). For many research and commercial applications, IVT of mRNA is typically performed using bacteriophage T7 RNA polymerase (T7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::edefe49c9a028c259b67bdfadea1f3ea
https://pubmed.ncbi.nlm.nih.gov/36357718
https://pubmed.ncbi.nlm.nih.gov/36357718
Autor:
Rameen Beroukhim, Nicholas L. Truex, Alexander R. Loftis, Xiaoli Liao, Bradley L. Pentelute, Zeyu Lu, Amy E. Rabideau, Meredith Brown, Brenton R. Paolella, John P. Busanovich
Publikováno v:
ACS Chem Biol
PMC
PMC
Copyright © 2020 American Chemical Society. Antisense oligonucleotide therapies are important cancer treatments, which can suppress genes in cancer cells that are critical for cell survival. SF3B1 has recently emerged as a promising gene target that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a52d3838b90588ed89d9b34e76fcc89
https://pubmed.ncbi.nlm.nih.gov/32348107
https://pubmed.ncbi.nlm.nih.gov/32348107
Autor:
Ruben C. Aguilar, Mike Lu, Swetha Ramadesikan, Nicholas L. Truex, Erin M. Kischuk, Andrew J. McCluskey, John Collier, Bradley L. Pentelute, Hristos Z. Kaimakliotis, Timothy L. Ratliff, Sneha Subramanian, Michael S. Santos, Deborah W. Knapp, Sherwin Jack, Bennett D. Elzey, Alexander R. Loftis, Amy E. Rabideau, Deepika Dhawan, Kayalvizhi Madhivanan, Michael O. Koch, Daniel F. Edwards
Publikováno v:
Int J Cancer
Bladder cancer is the sixth most common cancer in the United States, and it exhibits an alarming 70% recurrence rate. Thus, the development of more efficient antibladder cancer approaches is a high priority. Accordingly, this work provides the basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf35f3d972659bce11d61fa47cd1f1ce
https://europepmc.org/articles/PMC10303116/
https://europepmc.org/articles/PMC10303116/
Autor:
Bradley L. Pentelute, Amy E. Rabideau
Publikováno v:
ACS Chemical Biology. 11:1490-1501
The intracellular delivery of peptide and protein therapeutics is a major challenge due to the plasma membrane, which acts as a barrier between the extracellular environment and the intracellular milieu. Over the past two decades, a nontoxic PA/LFN d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e74c468a1e30789ce4afe927db9655a
https://doi.org/10.1021/acschembio.6b00169
https://doi.org/10.1021/acschembio.6b00169
Autor:
Bradley L. Pentelute, Amy E. Rabideau
Publikováno v:
ACS Central Science, Vol 1, Iss 8, Pp 423-430 (2015)
ACS Central Science
ACS Central Science
Eukaryotes have evolved the ubiquitin (Ub)/proteasome system to degrade polypeptides. The Ub/proteasome system is one way that cells regulate cytosolic protein and amino acids levels through the recognition and ubiquitination of a protein’s N-termi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f061db075e3ab360bc991faa75cc534
https://doaj.org/article/e5f9b56c89774e2faa1158faad1feab6
https://doaj.org/article/e5f9b56c89774e2faa1158faad1feab6
Publikováno v:
Chemical Science
Royal Society of Chemistry
Royal Society of Chemistry
Mirror image peptides have unique stability and immunogenic properties in mammals, making them attractive agents to investigate. Their properties inside cells have been mostly unexplored because biopolymers are difficult to transport across cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdbaa7b024de6d0cfae8574f58435ea
https://doi.org/10.1039/c4sc02078b
https://doi.org/10.1039/c4sc02078b
Autor:
Alex R. Loftis, Marco Biancucci, Zeyu Lu, Amy E. Rabideau, Bradley L. Pentelute, Karla J. F. Satchell
Ras/Rap1-specific endopeptidase (RRSP) is a cytotoxic effector domain of the multifunctional autoprocessing repeats-in-toxin (MARTX) toxin of highly virulent strains of Vibrio vulnificus. RRSP blocks RAS-MAPK kinase signaling by cleaving Ras and Rap1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af20b7969d1bed3286a49ebbf4db5dff
https://europepmc.org/articles/PMC5626579/
https://europepmc.org/articles/PMC5626579/
Autor:
Bradley L. Pentelute, Amy E. Rabideau, Mark D. Simon, Hansol Kang, Rocco L. Policarpo, Xiaoli Liao
Publikováno v:
Angewandte Chemie. 126:9357-9362
Sortase-mediated ligation (sortagging) is a versatile, powerful strategy for protein modification. Because the sortase reaction reaches equilibrium, a large excess of polyglycine nucleophile is often employed to drive the reaction forward and suppres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa710446b1c193bf5ad22a9570d9d21
https://doi.org/10.1002/ange.201403582
https://doi.org/10.1002/ange.201403582