Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Amy Donner"'
Autor:
Yuanjing Liu, Jean-Cosme Dodart, Helene Tran, Shaunna Berkovitch, Maurine Braun, Michael Byrne, Ann F. Durbin, Xiao Shelley Hu, Naoki Iwamoto, Hyun Gyung Jang, Pachamuthu Kandasamy, Fangjun Liu, Kenneth Longo, Jörg Ruschel, Juili Shelke, Hailin Yang, Yuan Yin, Amy Donner, Zhong Zhong, Chandra Vargeese, Robert H. Brown
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
C9orf72 expansion mutations are the most common genetic cause of ALS and FTD, which have limited therapies. The authors generate stereopure oligonucleotides that selectively deplete expansion-containing transcripts and protect against expansion-assoc
Externí odkaz:
https://doaj.org/article/c67a2cf526554819ac5be15eaecb07de
Publikováno v:
PLoS Biology, Vol 15, Iss 2, p e2001387 (2017)
Discovering new medicines is difficult and increasingly expensive. The pharmaceutical industry has responded to this challenge by embracing open innovation to access external ideas. Historically, partnerships were usually bilateral, and the drug disc
Externí odkaz:
https://doaj.org/article/32a96564037d465b8acda89974007c3e
Autor:
Pachamuthu Kandasamy, Ann Fiegen Durbin, Michael Byrne, Robert H. Brown, Jean-Cosme Dodart, Yuan Yin, Kenneth Longo, Amy Donner, Fangjun Liu, Xiao Shelley Hu, Naoki Iwamoto, Juili Dilip Shelke, Maurine Braun, Chandra Vargeese, Jörg Ruschel, Hailin Yang, Helene Tran, Shaunna Berkovitch, Yuanjing Liu, Zhong Zhong, Hyun Gyung Jang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
A large G4C2-repeat expansion in C9orf72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Neuronal degeneration associated with this expansion arises from a loss of C9orf72 protein, the accumu
Publikováno v:
Epigenetic Drug Discovery. :133-152
Autor:
Vani Katheria, Leana Chien, Rachel Tran, Enrique Soto-Perez-de-Celis, Mina S. Sedrak, Sherry Hite, Jessica Vazquez, Simone Fernandes Dos Santos Hughes, William Dale, Dhvani Bhatt, Peggy S. Burhenn, Amy Donner, Dale Mitani, Kemberly Charles, Elsa Roberts, Daneng Li
Publikováno v:
J Geriatr Oncol
Colleagues and team members of Arti Hurria, MD will remember that despite her lengthy list of achievements, she was always thinking to the future. Shortly before she passed, Dr. Hurria compiled a "Top 10 Dream List" of items she most wanted to accomp
Publikováno v:
PLoS Biology, Vol 15, Iss 2, p e2001387 (2017)
PLoS Biology
PLoS Biology
Discovering new medicines is difficult and increasingly expensive. The pharmaceutical industry has responded to this challenge by embracing open innovation to access external ideas. Historically, partnerships were usually bilateral, and the drug disc
Autor:
Amy, Donner
Publikováno v:
Nature chemical biology. 8(9)
Autor:
Amy, Donner
Publikováno v:
Nature chemical biology. 8(9)
Autor:
Amy, Donner
Publikováno v:
Nature chemical biology. 8(9)
Autor:
Greg Fisk, Amy Donner, Manfred Auer, James R. Rusche, Paul Rennert, Reed C. Doten, Thomas J. Daly, Herbert Jaksche
Publikováno v:
Biochemistry. 32:10497-10505
Recombinant HIV-1 Rev protein was overexpressed in Escherichia coli using translational coupling to the beta-glucuronidase gene and demonstrated to interact with high affinity and specificity with the Rev responsive element (RRE). A complex Rev-depen