Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Amy Dan"'
Autor:
Diana I. Albu, Benjamin J. Wolf, Yan Qin, Xianzhe Wang, Amy Daniel Ulumben, Mei Su, Vivian Li, Eirene Ding, Jose Angel Gonzalo, Jason Kong, Ruturaj Jadhav, Nelly Kuklin, Alberto Visintin, Bing Gong, Thomas J. Schuetz
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTCombinatorial strategies, such as targeting different immune checkpoint receptors, hold promise to increase the breadth and duration of the response to cancer therapy. Here we describe the preclinical evaluation of CTX-8371, a protein constru
Externí odkaz:
https://doaj.org/article/5e1ca35cffdd474daf5caef1c125a47e
Autor:
Garth A. Kinberger, Michael Tanowitz, Linda Fradkin, Michael E. Østergaard, Alfred E. Chappell, Jinghua Yu, Richard G. Lee, Michaela Jackson, Sue Murray, Amy Dan, Frank Rigo, C. Frank Bennett, Patrick Anderson, Tae-Won Kim, Rick Carty, Adam E. Mullick, Hans Gaus, Eric E. Swayze, Audrey Low, Thazha P. Prakash, Punit P. Seth, Rachel Q Peralta
Publikováno v:
Nucleic Acids Research
We determined the effect of attaching palmitate, tocopherol or cholesterol to PS ASOs and their effects on plasma protein binding and on enhancing ASO potency in the muscle of rodents and monkeys. We found that cholesterol ASO conjugates showed 5-fol
Autor:
Robin P. Goin-Kochel, Ivana Lozano, Gabrielle Duhon, Gabriela Marzano, Amy Daniels, J. Kiely Law, Katharine Diehl, LeeAnne Green Snyder, Pamela Feliciano, Wendy K. Chung, SPARK Consortium
Publikováno v:
Journal of Clinical and Translational Science, Vol 8 (2024)
Abstract Introduction: Under enrollment of participants in clinical research is costly and delays study completion to impact public health. Given that research personnel make decisions about which strategies to pursue and participants are the recipi
Externí odkaz:
https://doaj.org/article/ef327776bfc843108a7025f0a48539a7
Autor:
Karen Dyson, Andréa P. Nicolau, Karis Tenneson, Wendy Francesconi, Amy Daniels, Giulia Andrich, Bernardo Caldas, Silvia Castaño, Nathanael de Campos, John Dilger, Vinicius Guidotti, Iara Jaques, Ian M. McCullough, Allan D. McDevitt, Luis Molina, Dawn M. Nekorchuk, Tom Newberry, Cristiano Lima Pereira, Jorge Perez, Teal Richards-Dimitrie, Ovidio Rivera, Beatriz Rodriguez, Naiara Sales, Jhon Tello, Crystal Wespestad, Brian Zutta, David Saah
Publikováno v:
PLoS ONE, Vol 19, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/d9ee524e3a7348c68e795292bff1c2d5
Publikováno v:
Global Environmental Change. 20:472-482
In the U.S., public support for federal, state and local efforts to reduce greenhouse gases (GHGs) continues to be a crucial element of the political viability of these proposals. We present a detailed analysis of the reasons given by the general pub
Publikováno v:
Land Economics. 85:329-347
Respondents reported willingness to pay (WTP) for mitigating carbon dioxide emissions after structured group discussion or without this deliberation. Deliberation did not affect mean or median WTP, but it increased the number of issues respondents co
Publikováno v:
Risk Analysis. 29:425-437
Since the turn of the 21st century, there has been a revival of interest in nuclear power. Two decades ago, the expansion of nuclear power in the United States was halted by widespread public opposition as well as rising costs and less than projected
Publikováno v:
Climatic Change. 90:343-358
Discerning the general public's support of climate change policies is a significant part of understanding the political and social dynamics of mitigating climate change. National level surveys are a useful tool for furthering this understanding but p
Publikováno v:
Rural Sociology. 72:185-214
We investigated preferences for climate change mitigation policies and factors contributing to higher levels of policy support. The sample was comprised of 316 Michigan and Virginia residents, all of whom completed mail surveys. Of the eight policies
Autor:
Thazha P. Prakash, Husam S. Younis, Susan M. Freier, Melanie Katz, Stanley T. Crooke, C. Frank Bennett, Todd Machemer, Sebastien A. Burel, Huynh-Hoa Bui, Christopher E. Hart, Eric E. Swayze, Andrew T. Watt, Patrick Cauntay, Punit P. Seth, Mahyar Sabripour, Jill Hsiao, Scott P. Henry, Amy Dan, Gene Hung
Publikováno v:
Nucleic Acids Research
High affinity antisense oligonucleotides (ASOs) containing bicylic modifications (BNA) such as locked nucleic acid (LNA) designed to induce target RNA cleavage have been shown to have enhanced potency along with a higher propensity to cause hepatotox