Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Amy D. Laflin"'
Autor:
Ahmed S. Fahad, Cheng Yu Chung, Sheila N. López Acevedo, Nicoleen Boyle, Bharat Madan, Matías F. Gutiérrez-González, Rodrigo Matus-Nicodemos, Amy D. Laflin, Rukmini R. Ladi, John Zhou, Jacy Wolfe, Sian Llewellyn-Lacey, Richard A. Koup, Daniel C. Douek, Henry H. Balfour, David A. Price, Brandon J. DeKosky
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Adoptive immune therapies based on the transfer of antigen-specific T cells have been used successfully to treat various cancers and viral infections, but improved techniques are needed to identify optimally protective human T cell receptors
Externí odkaz:
https://doaj.org/article/eeee0fb53a204636b7baa68d6140de84
Autor:
Bailey B. Banach, Gabriele Cerutti, Ahmed S. Fahad, Chen-Hsiang Shen, Matheus Oliveira De Souza, Phinikoula S. Katsamba, Yaroslav Tsybovsky, Pengfei Wang, Manoj S. Nair, Yaoxing Huang, Irene M. Francino-Urdániz, Paul J. Steiner, Matías Gutiérrez-González, Lihong Liu, Sheila N. López Acevedo, Alexandra F. Nazzari, Jacy R. Wolfe, Yang Luo, Adam S. Olia, I-Ting Teng, Jian Yu, Tongqing Zhou, Eswar R. Reddem, Jude Bimela, Xiaoli Pan, Bharat Madan, Amy D. Laflin, Rajani Nimrania, Kwok-Yung Yuen, Timothy A. Whitehead, David D. Ho, Peter D. Kwong, Lawrence Shapiro, Brandon J. DeKosky
Publikováno v:
Cell Reports, Vol 37, Iss 1, Pp 109771- (2021)
Summary: Understanding mechanisms of protective antibody recognition can inform vaccine and therapeutic strategies against SARS-CoV-2. We report a monoclonal antibody, 910-30, targeting the SARS-CoV-2 receptor-binding site for ACE2 as a member of a p
Externí odkaz:
https://doaj.org/article/eeb91ec1080042a7abf186e7a830013e
Autor:
Kyle D. Apley, Stephanie N. Johnson, Brandon J. DeKosky, Cory Berkland, Noora Batrash, Amy D. Laflin, J. Daniel Griffin
Publikováno v:
Industrial & Engineering Chemistry Research. 60:16839-16853
Fc fusions are a growing class of drugs comprising an antibody Fc domain covalently linked to a protein or peptide and can pose manufacturing challenges. In this study we evaluated three synthetic ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34dcbd2314f017e0474cdb54e5318d5a
https://doi.org/10.1021/acs.iecr.1c02842
https://doi.org/10.1021/acs.iecr.1c02842
Autor:
Ahmed S Fahad, Cheng-Yu Chung, Sheila N Lopez Acevedo, Nicoleen Boyle, Bharat Madan, Matias F Gutiérrez-González, Rodrigo Matus-Nicodemos, Amy D Laflin, Rukmini R Ladi, John Zhou, Jacy Wolfe, Sian Llewellyn-Lacey, Richard A Koup, Daniel C Douek, Henry H Balfour Jr, David A Price, Brandon J DeKosky
Publikováno v:
Protein Eng Des Sel
Functional analyses of the T cell receptor (TCR) landscape can reveal critical information about protection from disease and molecular responses to vaccines. However, it has proven difficult to combine advanced next-generation sequencing technologies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c06b4d41bad58dde16f6e72aebfc5fb
https://europepmc.org/articles/PMC9005053/
https://europepmc.org/articles/PMC9005053/
Autor:
J. Zhou, D. Doueck, R. R. Ladi, Bharat Madan, Jacy R. Wolfe, N. Boyle, C. Yu Chung, David Price, S. N. Lopez Acevedo, Sian Llewellyn-Lacey, Rodrigo Matus-Nicodemos, A. S. Fahad, Amy D. Laflin, H. H. Balfour, Brandon J. DeKosky, Matias Gutiérrez-González
Functional analyses of the T cell receptor (TCR) landscape can reveal critical information about protection from disease and molecular responses to vaccines. However, it has proven difficult to combine advanced next-generation sequencing technologies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a0112137bee9700696c19aab0e78ec5
https://doi.org/10.1101/2021.10.19.465057
https://doi.org/10.1101/2021.10.19.465057
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0141479 (2015)
There are a variety of exciting hydrogel technologies being explored for cartilage regenerative medicine. Our overall goal is to explore whether using stem cells in an aggregate form may be advantageous in these applications. 3D stem cell aggregates
Externí odkaz:
https://doaj.org/article/a8f9ae76913044859f0d1b4aae7fba8f
Autor:
Irene M. Francino Urdániz, Timothy A. Whitehead, Ahmed S. Fahad, Bailey B. Banach, Adam S. Olia, Phinikoula S. Katsamba, Sheila N. Lopez Acevedo, Lihong Liu, Manoj S. Nair, Alexandra Nazzari, Yaoxing Huang, Jacy R. Wolfe, Amy D. Laflin, Bharat Madan, Xiaoli Pan, Matheus Oliveira de Souza, Jude Bimela, David D. Ho, Pengfei Wang, Kwok-Yung Yuen, I-Ting Teng, Jian Yu, Yaroslav Tsybovsky, Eswar R. Reddem, Rajani Nimrania, Lawrence Shapiro, Brandon J. DeKosky, Gabriele Cerutti, Peter D. Kwong, Paul J. Steiner, Matias Gutiérrez-González, Yang Luo, Chen-Hsiang Shen, Tongqing Zhou
Publikováno v:
SSRN Electronic Journal.
SummaryUnderstanding protective mechanisms of antibody recognition can inform vaccine and therapeutic strategies against SARS-CoV-2. We discovered a new antibody, 910-30, that targets the SARS-CoV-2 ACE2 receptor binding site as a member of a public
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f45786c42282959750a2c4ccb946de4
https://doi.org/10.2139/ssrn.3754549
https://doi.org/10.2139/ssrn.3754549
Publikováno v:
Cellular and Molecular Bioengineering. 11:99-115
INTRODUCTION: Spheroids of mesenchymal stem cells (MSCs) in cartilage tissue engineering have been shown to enhance regenerative potential owing to their 3D structure. In this study, we explored the possibility of priming spheroids under different me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b011f513f6568e35a055772696a1107
https://doi.org/10.1007/s12195-017-0517-4
https://doi.org/10.1007/s12195-017-0517-4
Autor:
Gabriele Cerutti, Yaroslav Tsybovsky, Bharat Madan, Bailey B. Banach, Matheus Oliveira de Souza, Adam S. Olia, Tongqing Zhou, I-Ting Teng, Yaoxing Huang, Jacy R. Wolfe, Phinikoula S. Katsamba, Peter D. Kwong, Pengfei Wang, Manoj S. Nair, Timothy A. Whitehead, Chen-Hsiang Shen, Ahmed S. Fahad, David D. Ho, Kwok-Yung Yuen, Irene M. Francino-Urdaniz, Brandon J. DeKosky, Jude Bimela, Lihong Liu, Eswar R. Reddem, Amy D. Laflin, Xiaoli Pan, Rajani Nimrania, Lawrence Shapiro, Jian Yu, Alexandra Nazzari, Sheila N. Lopez Acevedo, Paul J. Steiner, Matias Gutiérrez-González, Yang Luo
Publikováno v:
Cell Reports
bioRxiv
Cell Reports, Vol 37, Iss 1, Pp 109771-(2021)
bioRxiv
Cell Reports, Vol 37, Iss 1, Pp 109771-(2021)
Understanding mechanisms of protective antibody recognition can inform vaccine and therapeutic strategies against SARS-CoV-2. We report a monoclonal antibody, 910-30, targeting the SARS-CoV-2 receptor-binding site for ACE2 as a member of a public ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224e1d53c38741c783ef8b44c276f2f9
https://doi.org/10.1016/j.celrep.2021.109771
https://doi.org/10.1016/j.celrep.2021.109771
Autor:
Michael A. Holtz, BanuPriya Sridharan, Nicholas K. Wischmeier, Donna M. Pacicca, Amy D. Laflin, Michael S. Detamore
Publikováno v:
Journal of Orthopaedic Research. 35:1606-1616
To date, many osteochondral regenerative approaches have utilized varied combinations of biocompatible materials and cells to engineer cartilage. Even in cell-based approaches, to date, no study has utilized stem cell aggregates alone for regeneratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f60d2fbb38407bb33841ee0c747c486
https://doi.org/10.1002/jor.23467
https://doi.org/10.1002/jor.23467