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pro vyhledávání: '"Amy D. DeCastro"'
Autor:
Anand Palani, Min Lu, Jennifer O'Neil, Christopher Brynczka, Lisa Nogle, Amy C. Doty, Christian Fischer, Hai-Young Kim, Abdelghani Achab, Adam Beard, Nicole C. Walsh, Matthew Lloyd Childers, Kalyan Chakravarthy, Josep Saurí, Amy D. DeCastro, Peter W. Fan, Qinglin Pu, Richard A. Miller, Matthew J. Mitcheltree, Rachel L. Palte, Theodore A. Martinot, Hongjun Zhang, Symon Gathiaka, Roshi Afshar, Thomas W. Lyons, Spencer McMinn, Mangeng Cheng, Derun Li
Publikováno v:
Cancer Research. 81:297-297
Arginase overexpression has been associated with poor survival rates in advanced cancer patients treated with Keytruda. High levels of Arginase may lead to a depletion of arginine within the tumor microenvironment, inhibiting the immune response. Thu