Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Amy D Holdorf"'
Autor:
Juan I Fuxman Bass, Carles Pons, Lucie Kozlowski, John S Reece‐Hoyes, Shaleen Shrestha, Amy D Holdorf, Akihiro Mori, Chad L Myers, Albertha JM Walhout
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 10, Pp 1-19 (2016)
Abstract Transcription factors (TFs) play a central role in controlling spatiotemporal gene expression and the response to environmental cues. A comprehensive understanding of gene regulation requires integrating physical protein–DNA interactions (
Externí odkaz:
https://doaj.org/article/a6b21d56d5cf41ec85dc315ca42fac2b
Autor:
Emma Watson, Viridiana Olin-Sandoval, Michael J Hoy, Chi-Hua Li, Timo Louisse, Victoria Yao, Akihiro Mori, Amy D Holdorf, Olga G Troyanskaya, Markus Ralser, Albertha JM Walhout
Publikováno v:
eLife, Vol 5 (2016)
Metabolic network rewiring is the rerouting of metabolism through the use of alternate enzymes to adjust pathway flux and accomplish specific anabolic or catabolic objectives. Here, we report the first characterization of two parallel pathways for th
Externí odkaz:
https://doaj.org/article/e41dab67960c492ea49983dc8cb5e514
Autor:
Jote T. Bulcha, Gabrielle E. Giese, Md. Zulfikar Ali, Yong-Uk Lee, Melissa D. Walker, Amy D. Holdorf, L. Safak Yilmaz, Robert C. Brewster, Albertha J.M. Walhout
Publikováno v:
Cell Reports, Vol 26, Iss 2, Pp 460-468.e4 (2019)
Summary: Biological systems must possess mechanisms that prevent inappropriate responses to spurious environmental inputs. Caenorhabditis elegans has two breakdown pathways for the short-chain fatty acid propionate: a canonical, vitamin B12-dependent
Externí odkaz:
https://doaj.org/article/f885682baa464efda4376d890475dca9
Autor:
Sushila, Bhattacharya, Brent B, Horowitz, Jingyan, Zhang, Xuhang, Li, Hefei, Zhang, Gabrielle E, Giese, Amy D, Holdorf, Albertha J M, Walhout
Publikováno v:
iScience. 25(8)
Metabolic perturbations can affect gene expression, for instance to rewire metabolism. While numerous efforts have measured gene expression in response to individual metabolic perturbations, methods that determine all metabolic perturbations that aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69add1b7ce683f4f3d4cdd7b56ccde42
https://pubmed.ncbi.nlm.nih.gov/35847555
https://pubmed.ncbi.nlm.nih.gov/35847555
Publikováno v:
Current Opinion in Systems Biology. 15:12-18
Metabolic reactions form the basis of life to generate biomass, produce energy, and eliminate waste. Together, metabolic reactions function in the context of a highly interconnected metabolic network. Flux through this network needs to be adaptable d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efdd19997ce73b5687f525717095518f
https://doi.org/10.1016/j.coisb.2019.03.002
https://doi.org/10.1016/j.coisb.2019.03.002
Autor:
Brent B. Horowitz, Amy D. Holdorf, Gabrielle E. Giese, Huimin Na, Hefei Zhang, L. Safak Yilmaz, Yong-Uk Lee, Sushila Bhattacharya, Jingyan Zhang, Cédric Diot, Aurian P. García-González, Shivani Nanda, Melissa D. Walker, Xuhang Li, Albertha J.M. Walhout, Olga Ponomarova, Thomas Leland, Zeynep Mirza
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
In our group, we aim to understand metabolism in the nematode Caenorhabditis elegans and its relationships with gene expression, physiology and the response to therapeutic drugs. On March 15, 2020, a stay-at-home order was put into effect in the stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f3ef385972629f9ddb291dde5cd330
https://pubmed.ncbi.nlm.nih.gov/33398287
https://pubmed.ncbi.nlm.nih.gov/33398287
Autor:
Melissa D, Walker, Gabrielle E, Giese, Amy D, Holdorf, Sushila, Bhattacharya, Cédric, Diot, Aurian P, García-González, Brent, Horowitz, Yong-Uk, Lee, Thomas, Leland, Xuhang, Li, Zeynep, Mirza, Huimin, Na, Shivani, Nanda, Olga, Ponomarova, Hefei, Zhang, Jingyan, Zhang, L Safak, Yilmaz, Albertha J M, Walhout
Publikováno v:
bioRxiv : the preprint server for biology.
In our group, we aim to understand metabolism in the nematode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b646202903075aa3802963eef396f8f5
https://pubmed.ncbi.nlm.nih.gov/34117752
https://pubmed.ncbi.nlm.nih.gov/34117752
Publikováno v:
Genes to Cells. 22:770-784
Reverse genetic screens by RNA interference (RNAi) in model organisms such as the nematode Caenorhabditis elegans have provided numerous insights into gene function, thereby connecting genotype to phenotype. However, genes that contribute only subtly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80530788c19b1fafb6ad4a8bf48f9ff7
https://doi.org/10.1111/gtc.12516
https://doi.org/10.1111/gtc.12516
WormCat: an online tool for annotation and visualization of Caenorhabditis elegans genome-scale data
Autor:
Albertha J.M. Walhout, Anne C. Hart, Peter R. Boag, Amy D. Holdorf, Daniel P Higgins, Gregory J. Pazour, Amy K. Walker
Publikováno v:
Genetics
The emergence of large gene expression datasets has revealed the need for improved tools to identify enriched gene categories and visualize enrichment patterns. While gene ontogeny (GO) provides a valuable tool for gene set enrichment analysis, it ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf3c9c5735fc35a82770c6b5b8162de
https://doi.org/10.1101/844928
https://doi.org/10.1101/844928
Autor:
María Teresa Camacho Olmedo, Xuhang Li, Ye Shang, Amy D. Holdorf, Albertha J.M. Walhout, Jingyan Zhang, L. Safak Yilmaz, Marta Artal-Sanz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Host Microbe
instname
Cell Host Microbe
Iron is an essential micronutrient for all forms of life; low levels of iron cause human disease, while too much iron is toxic. Low iron levels induce reactive oxygen species (ROS) by disruption of the heme and iron-sulfur cluster-dependent electron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0dc6e36fe176aa140d239e65d7aa67
http://hdl.handle.net/10261/202101
http://hdl.handle.net/10261/202101