Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives

Autor: Xu Cao, Gopala K. Yakala, Francijna E. van den Hil, Amy Cochrane, Christine L. Mummery, Valeria V. Orlova

Publikováno v: Stem Cell Reports, Vol 12, Iss 6, Pp 1282-1297 (2019)

Summary: A renewable source of human monocytes and macrophages would be a valuable alternative to primary cells from peripheral blood (PB) in biomedical research. We developed an efficient protocol to derive monocytes and macrophages from human induc

Externí odkaz: https://doaj.org/article/e3756b571a5d4f7aa0fea3b76a814a7d

Scalable microphysiological system to model three-dimensional blood vessels

Autor: Mees N. S. de Graaf, Amy Cochrane, Francijna E. van den Hil, Wesley Buijsman, Andries D. van der Meer, Albert van den Berg, Christine L. Mummery, Valeria V. Orlova

Publikováno v: APL Bioengineering, Vol 3, Iss 2, Pp 026105-026105-11 (2019)

Blood vessel models are increasingly recognized to have value in understanding disease and drug discovery. However, continued improvements are required to more accurately reflect human vessel physiology. Realistic three-dimensional (3D) in vitro cult

Externí odkaz: https://doaj.org/article/b6ea00900bd847ce9a9bc4ecb3228a4d

Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology

Autor: Valeria V. Orlova, Christine L. Mummery, Amy Cochrane, Andries D. van der Meer, Hugo J. Albers, Albert van den Berg, Robert Passier

Publikováno v: Advanced Drug Delivery Reviews
Advanced Drug Delivery Reviews, 140, 68-77. ELSEVIER
Advanced drug delivery reviews, 140, 68-77. Elsevier

The vascular system is one of the first to develop during embryogenesis and is essential for all organs and tissues in our body to develop and function. It has many essential roles including controlling the absorption, distribution and excretion of c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a966bb87e3cafcd4fc63f51316c97f4c
http://www.scopus.com/inward/record.url?scp=85049085655&partnerID=8YFLogxK

Human iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease

Autor: Elisa, Giacomelli, Viviana, Meraviglia, Giulia, Campostrini, Amy, Cochrane, Cao, Xu, van Helden, Ruben W. J., Ana Krotenberg Garcia, Maria, Mircea, Sarantos, Kostidis, Davis, Richard P., van Meer, Berend J., Jost, Carolina R., Koster, Abraham J., Hailiang, Mei, Míguez, David G., Mulder, Aat A., Mario, Ledesma-Terrón, Giulio, Pompilio, Luca, Sala, Salvatori, Daniela C. F., Slieker, Roderick C., Elena, Sommariva, de Vries, Antoine A. F., Martin, Giera, Stefan, Semrau, Tertoolen, Leon G. J., Orlova, Valeria V., Bellin, Milena, Mummery, Christine L.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3657::d0b41116e637059dd476a16f82ad3005
http://hdl.handle.net/11577/3340284

Scalable microphysiological system to model three-dimensional blood vessels

Autor: Andries D. van der Meer, Amy Cochrane, Valeria V. Orlova, Mees N. S. de Graaf, Francijna E. van den Hil, Wesley Buijsman, Christine L. Mummery, Albert van den Berg

Publikováno v: APL BIOENGINEERING, 3(2). AMER INST PHYSICS
APL Bioengineering, 3
APL Bioengineering
APL Bioengineering, 3(2):026105. American Institute of Physics
APL Bioengineering, Vol 3, Iss 2, Pp 026105-026105-11 (2019)

Blood vessel models are increasingly recognized to have value in understanding disease and drug discovery. However, continued improvements are required to more accurately reflect human vessel physiology. Realistic three-dimensional (3D) in vitro cult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea27c7aca908063af0065463a82a2d82
http://hdl.handle.net/1887/3221384