Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Amy C. Richards Grayson"'
Publikováno v:
Advanced Drug Delivery Reviews. 56:173-184
Implantable electronic devices such as pacemakers and neural implants are often used for electrical stimulation. The usage of microfabrication techniques to produce microelectromechanical systems (MEMS) has allowed engineers to address a wider range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bddb630e34a61bf1e1408236d581e44d
https://doi.org/10.1016/j.addr.2003.07.012
https://doi.org/10.1016/j.addr.2003.07.012
Publikováno v:
Journal of Biomedical Materials Research. :502-512
A polymeric microreservoir device for controlled-release drug delivery relies on the degradation of thin poly(lactic-co-glycolic acid) membranes that seal each reservoir to achieve pulsatile drug delivery. In vitro release studies in which the swelli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1273cb5d64844961c08ad0b1bfacfcbc
https://doi.org/10.1002/jbm.a.30019
https://doi.org/10.1002/jbm.a.30019
Autor:
Amy C. Richards Grayson, Aaron Lynn, James M. Anderson, Robert Langer, Michael J. Cima, Gabriela Voskerician
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 15:1281-1304
The biocompatibility and biodegradation rate of component materials are critical when designing a drug-delivery device. The degradation products and rate of degradation may play important roles in determining the local cellular response to the implan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3639220be0f040748c828f68702e1d
https://doi.org/10.1163/1568562041959991
https://doi.org/10.1163/1568562041959991
Autor:
Rebecca S. Shawgo, Nolan T. Flynn, Audrey M. Johnson, Yawen Li, Amy C. Richards Grayson, Robert Langer, Michael J. Cima
Publikováno v:
Proceedings of the IEEE. 92:6-21
MEMS devices are manufactured using similar microfabrication techniques as those used to create integrated circuits. They often, however, have moving components that allow physical or analytical functions to be performed by the device. Although MEMS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff8c69dfaced24b7ca0160e565cf0fc
https://doi.org/10.1109/jproc.2003.820534
https://doi.org/10.1109/jproc.2003.820534
Autor:
Michael J. Cima, Insung S. Choi, Robert Langer, Amy C. Richards Grayson, Henry Brem, Betty Tyler, Paul P. Wang
Publikováno v:
Nature Materials. 2:767-772
Controlled-release drug delivery systems have many applications, including treatments for hormone deficiencies and chronic pain. A biodegradable device that could provide multi-dose drug delivery would be advantageous for long-term treatment of condi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479712852fb2f7373519a0b5a1f36dcb
https://doi.org/10.1038/nmat998
https://doi.org/10.1038/nmat998
Publikováno v:
Pharmaceutical research. 23(8)
The goals of this study were as follows: 1) to evaluate the efficacy of different polyethylenimine (PEI) structures for siRNA delivery in a model system, and 2) to determine the biophysical and structural characteristics of PEI that relate to siRNA d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2da764f4c0a41be5b2052614e937f26
https://pubmed.ncbi.nlm.nih.gov/16845585
https://pubmed.ncbi.nlm.nih.gov/16845585
Publikováno v:
Biomaterials. 26(14)
The component materials of controlled-release drug delivery systems are often selected based on their degradation rates. The release time of a drug from a system will strongly depend on the degradation rates of the component polymers. We have observe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6827220eef96fd57562fd7f7303e313
https://pubmed.ncbi.nlm.nih.gov/15576189
https://pubmed.ncbi.nlm.nih.gov/15576189