Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amy C Gottschalk"'
Publikováno v:
Neurotrauma Reports, Vol 3, Iss 1, Pp 178-184 (2022)
Transcriptomic investigations of traumatic brain injury (TBI) can give us deep insights into the pathological and compensatory processes post-injury. Thus far, transcriptomic studies in TBI have mostly used microarrays and have focused on rodent mode
Externí odkaz:
https://doaj.org/article/bf1da908014d45eeadf5e939970d1ed1
Autor:
Amy C. Gottschalk, Marco M. Hefti
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Microtubule associated proteins (MAPs), defined as proteins that bind microtubules but are not molecular motors or severing enzymes, play a key role in regulating microtubule stability in neurons. Existing studies of the evolutionary relatio
Externí odkaz:
https://doaj.org/article/ad668f62d2f74cdb994a556519b52901
Autor:
Ellen van der Plas, Jeffrey D. Long, Timothy R. Koscik, Vincent Magnotta, Darren G. Monckton, Sarah A. Cumming, Amy C. Gottschalk, Marco Hefti, Laurie Gutmann, Peggy C. Nopoulos
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
IntroductionThe present study had four aims. First, neuronal injury markers, including neurofilament light (NF-L), total tau, glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase (UCH-L1), were compared between individuals with a
Externí odkaz:
https://doaj.org/article/009018d5ab65499fb8768c4ab0e95700
Autor:
Ryan K. Betters, Emma Luhmann, Amy C. Gottschalk, Zhen Xu, Christopher P. Ptak, Kimberly L. Fiock, Lilliana C. Radoshevich, Marco M. Hefti
Tau phosphorylation and aggregation is the final common pathway for neuronal toxicity across multiple neurodegenerative diseases including Alzheimer disease, progressive supranuclear palsy, and corticobasal degeneration. We have previously shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86578f6286d292baaff46a8da5b1730e
https://doi.org/10.1101/2022.10.17.512532
https://doi.org/10.1101/2022.10.17.512532
Autor:
Joseph Laakman, Kyle S Conway, John L Blau, Amy C Gottschalk, Marcus B. Nashelsky, Renee L Eigsti, Marco M. Hefti, Fozia Ghafoor
Publikováno v:
J Neuropathol Exp Neurol
1p36 deletion syndrome is the most common terminal deletion syndrome, manifesting clinically as abnormal facies and developmental delay with frequent cardiac, skeletal, urogenital, and renal abnormalities. Limited autopsy case reports describe the ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce15f070a2c98de33d5c42d561013b1
https://doi.org/10.1093/jnen/nlab072
https://doi.org/10.1093/jnen/nlab072
Autor:
Ryan K. Betters, Emma Luhmann, Amy C. Gottschalk, Zhen Xu, Mallory R. Shin, Christopher P. Ptak, Kimberly L. Fiock, Lilliana C. Radoshevich, Marco M. Hefti
Publikováno v:
eneuro. 10:ENEURO.0503-22.2023
Despite exhibiting tau phosphorylation similar to Alzheimer’s disease (AD), the human fetal brain is remarkably resilient to tau aggregation and toxicity. To identify potential mechanisms for this resilience, we used co-immunoprecipitation (co-IP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ff719116cd77dbbe2eb664c8a9409b
https://doi.org/10.1523/eneuro.0503-22.2023
https://doi.org/10.1523/eneuro.0503-22.2023