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Akademický článek

Mutational analysis of pentabrominated diphenyl-induced hepatocellular tumors in rats and mice, tissue levels of PBDE congeners in rats and mice, and AhR genotyping of Wistar Han rats

Autor: June K. Dunnick, Arun R. Pandiri, B.A. Merrick, Grace E. Kissling, Helen Cunny, Esra Mutlu, Suramya Waidyanatha, Robert C. Sills, Hue-Hua. L. Hong, Thai-Vu Ton, Timonthy Maynor, Leslie Rescio, Siuzanne L. Phillips, Michael J. Devito, Amy Brix

Publikováno v: Data in Brief, Vol 21, Iss , Pp 2125-2128 (2018)

This article describes data related to the research article entitled “Carcinogenic activity of pentabrominated diphenyl ether mixture (DE-71) in rats and mice” (Dunnick et al., 2018). PBDE-induced hepatocellular tumors harbored Hras and Ctnnb1 mu

Externí odkaz: https://doaj.org/article/49a0e9e4a1bb4fab94be71dec77a6871

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DNA Methylation Changes in Tbx3 in a Mouse Model Exposed to Polybrominated Diphenyl Ethers

Autor: Takashi Shimbo, Amy Brix, Deepak Mav, Paul A. Wade, June K. Dunnick, John Roberts, Ruchir R. Shah

Publikováno v: International Journal of Toxicology. 36:229-238

DE-71, a commercial mixture of polybrominated diphenyl ethers widely used in flame retardants, is a pervasive environmental contaminant due to its continuing release from waste material and its long half-life in humans. Although the genotoxic potenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b203030d5243571bc933665f7245eafc
https://doi.org/10.1177/1091581817706676

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Hepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats

Autor: J. Michael Sanders, T. V. Ton, Daniel L. Morgan, Kevin Gerrish, Gregory S. Travlos, Arun R. Pandiri, June K. Dunnick, Keith R. Shockley, Amy Brix

Publikováno v: Archives of Toxicology. 91:1685-1696

N,N-dimethyl-p-toluidine (DMPT), an accelerant for methyl methacrylate monomers in medical devices, was a liver carcinogen in male and female F344/N rats and B6C3F1 mice in a 2-year oral exposure study. p-Toluidine, a structurally-related chemical, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a432c141722abc62c3cbf66e79f82c1
https://doi.org/10.1007/s00204-016-1831-7

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The Course of Toxicity in the Pregnant Mouse After Exposure to the Cyanobacterial Toxin Cylindrospermopsin: Clinical Effects, Serum Chemistries, Hematology, and Histopathology

Autor: D. M. Hill, Robert D. Zehr, Gregory S. Travlos, David E. Malarkey, M. I. Gage, Amy Brix, Neil Chernoff, Judy Schmid, Ellen H. Rogers

Publikováno v: Journal of Toxicology and Environmental Health, Part A. 77:1040-1060

Cylindrospermopsin (CYN) is a toxin produced by a variety of fresh-water cyanobacterial species worldwide and induces significant adverse effects in both livestock and humans. This study investigated the course of CYN-induced toxicity in pregnant mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32823465fbe3ae833af6a7254fa5f9fa
https://doi.org/10.1080/15287394.2014.919838

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N,N-Dimethyl-p-toluidine, a Component in Dental Materials, Causes Hematologic Toxic and Carcinogenic Responses in Rodent Model Systems

Autor: J. M. Sanders, Gregory S. Travlos, Amy Brix, June K. Dunnick

Because of the potential for exposure to N, N-dimethyl- p-toluidine (DMPT) in medical devices and the lack of toxicity and carcinogenicity information available in the literature, the National Toxicology Program conducted toxicity and carcinogenicity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac8cc7c62b6eaa47cc6d154ff3644da
https://europepmc.org/articles/PMC5791536/

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Characterization of polybrominated diphenyl ether toxicity in Wistar Han rats and use of liver microarray data for predicting disease susceptibilities

Autor: Keith R. Shockley, Helen Cunny, Amy Brix, Molly Vallant, June K. Dunnick

The toxicity of polybrominated diphenyl ethers (PBDEs), flame-retardant components, was characterized in offspring from Wistar Han dams exposed by gavage to a PBDE mixture (DE71) starting at gestation day 6 and continuing to weaning on postnatal day

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547de4e9ac3ab85c5b14d739fd2e0ab6
https://europepmc.org/articles/PMC4816085/

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Exposure to tetrachloroazobenzene (TCAB) for 2 years in B6C3F1 mice is associated with inflammatory and chloracne-like skin lesions

Autor: Abraham Zlotogorski, Yuval Ramot, Abraham Nyska, David E. Malarkey, Gordon P. Flake, Alex Maly, Amy Brix, Grace E. Kissling, Warren G. Lieuallen, Michelle Hooth

Publikováno v: Toxicology Letters. 180:S54

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd1d356c3380cb727726c7bf0b89889e
https://doi.org/10.1016/j.toxlet.2008.06.627

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Safety of OP-1 (BM P-7) for Posterolateral Fusion in a Canine Model

Autor: Mark N. Hadley, Michael J. Rauzzino, Carl Lauryssen, Amy Brix, Christopher G. Paramore, Van R. Wadlington, Cheryl A. Palmer

Publikováno v: Neurosurgery. 43:703-703

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::753a5d72764af03124632f15be7a4d78
https://doi.org/10.1097/00006123-199809000-00307

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