Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Amy Belton"'
Autor:
Lingling Xian, Dan Georgess, Tait Huso, Leslie Cope, Amy Belton, Yu-Ting Chang, Wenyong Kuang, Qihua Gu, Xiaoyan Zhang, Stefania Senger, Alessio Fasano, David L. Huso, Andrew J. Ewald, Linda M. S. Resar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The function of high mobility group A1 (Hmga1) chromatin remodelling proteins in intestinal stem cells (ISC) is unknown. Here, the authors show that Hmga1 amplifies Wnt/β-catenin signalling to enhance self-renewal and inducesSox9to expand the Paneth
Externí odkaz:
https://doaj.org/article/5e3c00d6fe3d4dd9b4ee8a6610a4fe99
Autor:
Sandeep N Shah, Leslie Cope, Weijie Poh, Amy Belton, Sujayita Roy, C Conover Talbot, Saraswati Sukumar, David L Huso, Linda M S Resar
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63419 (2013)
Emerging evidence suggests that tumor cells metastasize by co-opting stem cell transcriptional networks, although the molecular underpinnings of this process are poorly understood. Here, we show for the first time that the high mobility group A1 (HMG
Externí odkaz:
https://doaj.org/article/2652faf1f1464808afb5edb5567c23ae
Autor:
Amy Belton, Alexander Gabrovsky, Young Kyung Bae, Ray Reeves, Christine Iacobuzio-Donahue, David L Huso, Linda M S Resar
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30034 (2012)
BackgroundAlthough metastatic colon cancer is a leading cause of cancer death worldwide, the molecular mechanisms that enable colon cancer cells to metastasize remain unclear. Emerging evidence suggests that metastatic cells develop by usurping trans
Externí odkaz:
https://doaj.org/article/cf7f5c65cba94c97b365e6fa24a397bf
Autor:
Sandeep N Shah, Candace Kerr, Leslie Cope, Elias Zambidis, Cyndi Liu, Joelle Hillion, Amy Belton, David L Huso, Linda M S Resar
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48533 (2012)
BackgroundAlthough recent studies have identified genes expressed in human embryonic stem cells (hESCs) that induce pluripotency, the molecular underpinnings of normal stem cell function remain poorly understood. The high mobility group A1 (HMGA1) ge
Externí odkaz:
https://doaj.org/article/bf1d8137a917472cac9e7e1d97cda020
Autor:
Linda M.S. Resar, Stanley Zucker, Biju Joseph, Amy Belton, Surajit Dhara, Charles M. Rudin, John Poirier, Jodi Segal, Ossama Elbahloul, Jeanne Kowalski, Francescopaolo Di Cello, Raka Bhattacharya, Mita Mukherjee, Lisa J. Wood, Joelle Hillion
Supplementary Data from Upregulation of MMP-2 by HMGA1 Promotes Transformation in Undifferentiated, Large-Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960c4e3c29d2cac891db85bb1516cc7f
https://doi.org/10.1158/1541-7786.22518817.v1
https://doi.org/10.1158/1541-7786.22518817.v1
Autor:
Linda M.S. Resar, Stanley Zucker, Biju Joseph, Amy Belton, Surajit Dhara, Charles M. Rudin, John Poirier, Jodi Segal, Ossama Elbahloul, Jeanne Kowalski, Francescopaolo Di Cello, Raka Bhattacharya, Mita Mukherjee, Lisa J. Wood, Joelle Hillion
Although lung cancer is the leading cause of cancer death worldwide, the precise molecular mechanisms that give rise to lung cancer are incompletely understood. Here, we show that HMGA1 is an important oncogene that drives transformation in undiffere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881f8a11aca5640e8613e10e708cdf7f
https://doi.org/10.1158/1541-7786.c.6542131
https://doi.org/10.1158/1541-7786.c.6542131
Autor:
Linda M. S. Resar, Raka Bhattacharya, Jeanne Kowalski, Ossama Elbahlouh, Ray Reeves, Kelsey Wertzler, Ying-Wei Lin, Peter Aplan, Richard Jove, Zhaohui Ye, Linzhao Cheng, Souyma Jaganathan, James Turkson, Amy Belton, Francescopaolo Di Cello, Mita Mukherjee, Takita Felder Sumter, Surajit Dhara, Joelle Hillion
Supplementary Table 1 from The High-Mobility Group A1a/Signal Transducer and Activator of Transcription-3 Axis: An Achilles Heel for Hematopoietic Malignancies?
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4075e67f0722337f871272108b25e6a2
https://doi.org/10.1158/0008-5472.22377134
https://doi.org/10.1158/0008-5472.22377134
Autor:
Linda M. S. Resar, Raka Bhattacharya, Jeanne Kowalski, Ossama Elbahlouh, Ray Reeves, Kelsey Wertzler, Ying-Wei Lin, Peter Aplan, Richard Jove, Zhaohui Ye, Linzhao Cheng, Souyma Jaganathan, James Turkson, Amy Belton, Francescopaolo Di Cello, Mita Mukherjee, Takita Felder Sumter, Surajit Dhara, Joelle Hillion
Supplementary Table 2 from The High-Mobility Group A1a/Signal Transducer and Activator of Transcription-3 Axis: An Achilles Heel for Hematopoietic Malignancies?
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dec391a7a10eb4432efeea2f05bf051
https://doi.org/10.1158/0008-5472.22377128
https://doi.org/10.1158/0008-5472.22377128
Autor:
Michael Koo, James Turkson, David L. Huso, Tait Huso, Patrick T. Gunning, Lingling Xian, Guosheng Liu, Brent D. G. Page, Amy Belton, Li Z. Luo, Linda M.S. Resar
Publikováno v:
Leukemia & Lymphoma. 57:2681-2684
Despite dramatic improvements in treatment and survival, acute lymphoid malignancies remain the leading cause of death in children with cancer and a highly lethal malignancy in adults.[1] Acute lym...
Autor:
Michael Williams, Linda M.S. Resar, Herbert H. Hill, Raymond Reeves, Amy Belton, William F. Siems, Jeong-Jin Park, Xing Zhang, David R. Gang, Lingling Xian, Tait Huso
Publikováno v:
Journal of Proteome Research. 14:1420-1431
Although significant progress has been made in the diagnosis and treatment of colorectal cancer (CRC), it remains a leading cause of cancer death worldwide. Early identification and removal of polyps that may progress to overt CRC is the cornerstone