Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Amy B. Hall"'
Autor:
Karl Patrick Gilbert, David Newsome, Howard Li, George M. Whitesides, Matthew R. Lockett, Kyaw Thu Minn, Hillier Shawn M, Karen A. Simon, Brenda K. Eustace, Diane M. Boucher, Amy B. Hall, Bobak Mosadegh
Publikováno v:
Biomaterials. 52:262-271
This work describes a 3D, paper-based assay that can isolate sub-populations of cells based on their invasiveness (i.e., distance migrated in a hydrogel) in a gradient of concentration of oxygen (O2). Layers of paper impregnated with a cell-compatibl
Publikováno v:
Biochemical Pharmacology. 91:129-134
Stem cells subserve repair functions for the lifetime of the organism but, as a consequence of this responsibility, are candidate cells for accumulating numerous genetic and/or epigenetic aberrations leading to malignant transformation. However, give
Autor:
Neal F. Gordon, Jeffrey A. Radding, Amy B. Hall, Cheryl Murphy, Nathan C. Tedford, James R. Graham
Publikováno v:
PROTEOMICS. 9:1469-1487
Protein phosphorylation is a primary form of information transfer in cell signaling pathways and plays a crucial role in regulating biological responses. Aberrant phosphorylation has been implicated in a number of diseases, and kinases and phosphatas
Autor:
James R. Graham, Amy B. Hall, Cheryl Murphy, Christine Rauh-Adelmann, Timothy K. Nadler, Lucy G. Yen, Neal F. Gordon, Jeffrey A. Radding
Publikováno v:
SLAS Discovery. 13:626-637
Cellular homeostasis and responses to stimuli are mediated by complex signaling network events dominated by changes in protein phosphorylation states. Understanding information flow in the network is essential for correlating signaling changes to cel
Autor:
Diane M. Boucher, Matthew R. Lockett, Bobak Mosadegh, Amy B. Hall, Karen A. Simon, Marym R. Mohammady, Taturo Udagawa, Brenda K. Eustace, Hillier Shawn M, Kyaw Thu Minn, George M. Whitesides
Publikováno v:
Biomaterials. 95
This work demonstrates the application of a 3D culture system-Cells-in-Gels-in-Paper (CiGiP)-in evaluating the metabolic response of lung cancer cells to ionizing radiation. The 3D tissue-like construct-prepared by stacking multiple sheets of paper c
Autor:
Michael Glogauer, M. Angelica Martinez Gakidis, Joan S. Brugge, Julie L. Wilsbacher, Amy B. Hall, Wojciech Swat, Sizhen Gao
Publikováno v:
Immunity. 24:305-316
Vav guanine nucleotide exchange factors (GEFs) have been implicated in cell adhesion by integrin and immune response receptors through the regulation of Rho GTPases. Here, we examine the role of Vav and Rho GTPases in phagocytosis by using primary mu
Publikováno v:
Current Biology. 13:308-314
Sprouty was originally identified in a genetic screen in Drosophila as an antagonist of fibroblast (FGF) and epidermal growth factor (EGF) signaling [1, 2]. Subsequently, four vertebrate homologs were discovered; among these, the human homolog Sprout
Publikováno v:
Proceedings of the National Academy of Sciences. 99:6041-6046
Signal transduction through epidermal growth factor receptors (EGFRs) is essential for the growth and development of multicellular organisms. A genetic screen for regulators of EGFR signaling has led to the identification of Sprouty, a cell autonomou
Autor:
Crystal Tolman, Philip Michael Reaper, Dave Newsome, Yong Gu, Brian Hare, Peter A. Charlton, Jean-Damien Charrier, Sean Milton, Mark Wood, Mac Johnson, Diane M. Boucher, Yuxin Wang, Brenda K. Eustace, Howard Li, Golec Julian M C, Darin Takemoto, Amy B. Hall, Cheryl Murphy, John Pollard, Brinley Furey
Publikováno v:
Oncotarget
// Amy B. Hall 1,* , Dave Newsome 1,* , Yuxin Wang 1,* , Diane M. Boucher 1 , Brenda Eustace 1 , Yong Gu 1 , Brian Hare 1 , Mac A. Johnson 1 , Howard Li 1 , Sean Milton 1 , Cheryl E. Murphy 1 , Darin Takemoto 1 , Crystal Tolman 1 , Mark Wood 1 , Pete
Autor:
Dina Shlyakhter, Mark Wood, Brenda K. Eustace, Diane M. Boucher, Elaine Krueger, Yong Gu, Anna Lindquist, Yuxin Wang, Amy B. Hall, Cheryl Murphy
Publikováno v:
Molecular Cancer Research. 14:B24-B24
Non-small cell lung cancer (NSCLC) is a prevalent and deadly disease because of high incidence and relapse rates. One hypothesis for the high relapse rate is the existence of cancer stem cells (CSCs), a rare subpopulation of cells within these tumors