Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Amy B, Emerman"'
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100748 (2014)
Accurate chromosome segregation is essential for cell viability. The mitotic spindle is crucial for chromosome segregation, but much remains unknown about factors that regulate spindle assembly. Recent work implicates RNA in promoting proper spindle
Externí odkaz:
https://doaj.org/article/e9de5420f44d44dc889bee59844a769a
Autor:
Amy B. Emerman, Michael D. Blower
Publikováno v:
Journal of Biological Chemistry. 293:12593-12605
RNA-binding proteins (RBP) are critical regulators of gene expression. Recent studies have uncovered hundreds of mRNA-binding proteins that do not contain annotated RNA-binding domains and have well-established roles in other cellular processes. Inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55e24a1cec4367207e10e9156107f862
https://doi.org/10.1074/jbc.ra118.003718
https://doi.org/10.1074/jbc.ra118.003718
Publikováno v:
RNA. 21:279-295
ADAR (adenosine deaminase acting on RNA) is an RNA-editing enzyme present in most metazoans that converts adenosines in double-stranded RNA targets into inosines. Although the RNA targets of ADAR-mediated editing have been extensively cataloged, our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4c2ef5e4be4a445f192c095dac5019
https://doi.org/10.1261/rna.047787.114
https://doi.org/10.1261/rna.047787.114
Autor:
Charles Elfe, Cynthia L. Hendrickson, Theodore B. Davis, Amy B. Emerman, Fiona A. Stewart, Kruti M. Patel, Eileen T. Dimalanta, Salvatore Russello, Sarah K. Bowman, Scott M. Adams, Andrew Barry, Evan Mauceli
Publikováno v:
Cancer Research. 78:3416-3416
Efficient utilization of targeted gene panels for clinical research is challenged by the wide variation in gene constituents specific to a given study. While focused gene panels efficiently provide the necessary depth of coverage for low-frequency va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1cc31b8d9cb779bcc4ec47104282910
https://doi.org/10.1158/1538-7445.am2018-3416
https://doi.org/10.1158/1538-7445.am2018-3416
Autor:
Sarah K. Bowman, Cynthia L. Hendrickson, Scott M. Adams, Theodore B. Davis, Andrew Barry, Charles Elfe, Evan Mauceli, Amy B. Emerman, Kruti M. Patel
Publikováno v:
Cancer Research. 78:1422-1422
Comprehensive genetic evaluation of patients with blood cancer can be imperative for identifying and classifying myeloid malignancies in a patient. Since liquid tumors comprise of highly variable percentages of normal cells or multiple tumor clones,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6caab10053b30a2955906e2d74748b0a
https://doi.org/10.1158/1538-7445.am2018-1422
https://doi.org/10.1158/1538-7445.am2018-1422
Autor:
Noa Henig, Amy B. Emerman, Kruti M. Patel, Sarah K. Bowman, Andrew Barry, Andrew F. Gardner, Cynthia L. Hendrickson
Publikováno v:
Current Protocols in Molecular Biology
Next-generation sequencing (NGS) is a powerful tool for genomic studies, translational research, and clinical diagnostics that enables the detection of single nucleotide polymorphisms, insertions and deletions, copy number variations, and other genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fcc39d56f219ccb1622ccfa623e8a0
https://pubmed.ncbi.nlm.nih.gov/28678441
https://pubmed.ncbi.nlm.nih.gov/28678441
Autor:
Scott M. Adams, Theodore B. Davis, Charles Elfe, Amy B. Emerman, Andrew Barry, Sarah K. Bowman, Noa Henig, Kruti M. Patel, Cynthia L. Hendrickson, Salvatore Russello
Publikováno v:
Cancer Research. 77:5362-5362
The screening and detection of germline BRCA1 and BRCA2 mutations are critical for the effective management of patients with breast or ovarian cancer and for the identification of individuals with a high risk of developing these cancers. In addition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cfdd0dc19e38294a02bcde517322e16
https://doi.org/10.1158/1538-7445.am2017-5362
https://doi.org/10.1158/1538-7445.am2017-5362
Autor:
Charles Elfe, Cynthia L. Hendrickson, Scott V. Adams, Kruti M. Patel, Sarah K. Bowman, Salvatore Russello, Noa Henig, Ted B. Davis, Andrew Barry, Amy B. Emerman
Publikováno v:
Cancer Research. 77:495-495
Variations in copy number are the most common type of DNA structural variations. Many of these alterations are associated with disease or indicate disease susceptibility. Detection of copy number variants (CNVs) for clinical applications requires eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4ee7f8457d716be79005f01218b459
https://doi.org/10.1158/1538-7445.am2017-495
https://doi.org/10.1158/1538-7445.am2017-495
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1413
RNAs associate with the mitotic spindle in a variety of organisms, where they can spatially regulate protein production, ensure their proper segregation during cell division, or perform translation-independent roles in spindle formation. The identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::913b521c140fb261228eb9f0ff98829b
https://pubmed.ncbi.nlm.nih.gov/27193857
https://pubmed.ncbi.nlm.nih.gov/27193857
Publikováno v:
Methods in Molecular Biology ISBN: 9781493935406
RNAs associate with the mitotic spindle in a variety of organisms, where they can spatially regulate protein production, ensure their proper segregation during cell division, or perform translation-independent roles in spindle formation. The identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d209aa8147772f8f8595eb0e070c0dd
https://doi.org/10.1007/978-1-4939-3542-0_19
https://doi.org/10.1007/978-1-4939-3542-0_19
