Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Amy A. Rand"'
Autor:
Amy A. Rand, Anita Rajamani, Sean D. Kodani, Todd R. Harris, Lukas Schlatt, Bodgan Barnych, Anthony G. Passerini, Bruce D. Hammock
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 12, Pp 1996-2005 (2019)
Epoxyeicosatrienoic acids (EETs) are formed from the metabolism of arachidonic acid by cytochrome P450s. EETs promote angiogenesis linked to tumor growth in various cancer models that is attenuated in vivo by cyclooxygenase 2 (COX-2) inhibitors. This
Externí odkaz:
https://doaj.org/article/94c1bac4420240c9a574f864c97208b8
Autor:
Todd R. Harris, Julie A. Griffith, Colleen E. C. Clarke, Krista L. Garner, Elizabeth C. Bowdridge, Evan DeVallance, Kevin J. Engles, Thomas P. Batchelor, William T. Goldsmith, Kim Wix, Timothy R. Nurkiewicz, Amy A. Rand
Publikováno v:
Environmental Science: Advances. 2:740-748
A LC-MS/MS based platform is used to gain a global perspective on shifts in oxylipids, signaling molecules derived from dietary lipids that modulate the inflammatory response, after nano-TiO2 inhalation exposure.
Autor:
Whitney M. Conard, Heather D. Whitehead, Keegan J. Harris, Gary A. Lamberti, Graham F. Peaslee, Amy A. Rand
Publikováno v:
Environmental Science & Technology Letters. 9:937-942
Publikováno v:
Environmental sciencetechnology. 56(20)
Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals reported in cosmetics and personal care products as ingredients, possible impurities in the raw material manufacturing process, or degradation products. The purpose of this study
Autor:
Oluwadamilola Daramola, Amy A. Rand
Publikováno v:
Environmental Science: Processes & Impacts. 23:1688-1695
The biotransformation of 6:2 fluorotelomer alcohol (6:2 FTOH) results in the production of bioactive and persistent metabolites, including perfluorinated carboxylic acids (PFCAs). While the products of 6:2 FTOH metabolism have been elucidated in seve
Autor:
Bruce D. Hammock, Bodgan Barnych, Sean D. Kodani, Lukas Schlatt, Anthony G. Passerini, Amy A. Rand, Todd R. Harris, Anita Rajamani
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 12, Pp 1996-2005 (2019)
Journal of lipid research, vol 60, iss 12
J Lipid Res
Journal of lipid research, vol 60, iss 12
J Lipid Res
Epoxyeicosatrienoic acids (EETs) are formed from the metabolism of arachidonic acid by cytochrome P450s. EETs promote angiogenesis linked to tumor growth in various cancer models that is attenuated in vivo by cyclooxygenase 2 (COX-2) inhibitors. This
Autor:
Amy A. Rand, Bruce D. Hammock, Shirley J. Gee, Bora Inceoglu, Natalia Vasylieva, Bogdan Barnych
Publikováno v:
Analytical chemistry, vol 89, iss 10
Tetramethylenedisulfotetramine (TETS, tetramine) is a formerly used and highly neurotoxic rodenticide. Its lethality, recent history of intentional use for mass poisoning, and the absence of a known antidote raise public health concerns. Therefore, r
Publikováno v:
Organic & biomolecular chemistry, vol 15, iss 20
COX metabolites of 8,9-EET, previously observed as potent mitogenic lipid mediators, were synthesized for the first time by using two synthetic approaches. These synthetic materials allow for structural confirmation of COX metabolites of 8,9-EET and
Autor:
Sean D. Kodani, Amy A. Rand, Denise M. Imai, Sung Hee Hwang, Bruce D. Hammock, Todd R. Harris, Jun Yang
Publikováno v:
Molecular pharmacology, vol 94, iss 2
The cyclooxygenase-2 (COX-2) selective inhibitor celecoxib is widely used in the treatment of pain and inflammation. Celecoxib has been explored as a possible treatment of liver fibrosis with contradictory results, depending on the model. The present
Autor:
Karen M. Kalanetra, Jennifer T. Smilowitz, J. Bruce German, Malin L. Nording, Amy A. Rand, Diana H. Taft, Bruce D. Hammock, Melissa A. Breck, David A. Mills, Candace S. Bever
Publikováno v:
Chemosphere. 203
Triclosan is frequently used for its antimicrobial properties and has been detected in human serum, urine, and breast milk. Animal and molecular studies have shown that triclosan exerts a wide range of adverse health effects at both high (ppm) and lo