Výsledky vyhledávání - "Amy A. Powers"

Akademický článek

Isoforms of Neuropilin-2 Denote Unique Tumor-Associated Macrophages in Breast Cancer

Autor: Rajeev Dhupar, Katherine E. Jones, Amy A. Powers, Seth H. Eisenberg, Kai Ding, Fangyuan Chen, Cecile Nasarre, Zhanpeng Cen, Yi-Nan Gong, Amanda C. LaRue, Elizabeth S. Yeh, James D. Luketich, Adrian V. Lee, Steffi Oesterreich, Michael T. Lotze, Robert M. Gemmill, Adam C. Soloff

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Tumor-associated macrophages (TAMs) exert profound influence over breast cancer progression, promoting immunosuppression, angiogenesis, and metastasis. Neuropilin-2 (NRP2), consisting of the NRP2a and NRP2b isoforms, is a co-receptor for heparin-bind

Externí odkaz: https://doaj.org/article/827b40d579f747be836c2d0874271b4e

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Akademický článek

HMGB1 Promotes Myeloid Egress and Limits Lymphatic Clearance of Malignant Pleural Effusions

Autor: Adam C. Soloff, Katherine E. Jones, Amy A. Powers, Pranav Murthy, Yue Wang, Kira L. Russell, Miranda Byrne-Steele, Amanda W. Lund, Jian-Min Yuan, Sara E. Monaco, Jian Han, Rajeev Dhupar, Michael T. Lotze

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Pleural effusions, when benign, are attributed to cardiac events and suffusion of fluid within the pleural space. When malignant, lymphatic obstruction by tumor and failure to absorb constitutively produced fluid is the predominant formulation. The p

Externí odkaz: https://doaj.org/article/5a91f8982a8f4d58a0286b73dfb64139

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Abstract A019: Targeting STAT3 for lung cancer prevention

Autor: Jill M. Siegfried, Adam C. Soloff, Autumn Gaither Davis, Amy A. Powers, Seth H. Eisenberg, Laura P. Stabile

Publikováno v: Cancer Prevention Research. 15:A019-A019

Former smokers have an elevated risk of lung cancer and account for a large proportion of newly diagnosed lung cancer. Former smokers with airway dysplasia have received modest benefit in randomized chemoprevention trials, while active smokers have n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e588ac6069556b089c413ca8f5b101df
https://doi.org/10.1158/1940-6215.tacpad22-a019

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680 Isoforms of neuropilin-2 regulate distinct macrophage functions and are associated with unique tumor-associated macrophages in murine and human breast cancer

Autor: Amy A. Powers, Amanda C. LaRue, Steffi Oesterreich, Michael T. Lotze, Seth H. Eisenberg, Adrian V. Lee, Fangyuan Chen, James D. Luketich, Katherine E. Jones, Kai Ding, Robert M. Gemmill, Rajeev Dhupar, Elizabeth S. Yeh, Adam C. Soloff, Cecile Nasarre

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

BackgroundTumor-associated macrophages (TAMs) exert profound influence over breast cancer progression, promoting immunosuppression, angiogenesis, and metastasis.1 Neuropilin-2 (NRP2), consisting of NRP2a and NRP2b isoforms, is a co-receptor for hepar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662c1ce3cea188d61a775a4c65bdeca0
https://doi.org/10.1136/jitc-2021-sitc2021.680

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Experimental respiratory exposure to putative Gulf War toxins promotes persistent alveolar macrophage recruitment and pulmonary inflammation

Autor: Seth H. Eisenberg, John P. Ryan, Amy A. Powers, Michael T. Lotze, Katherine E. Jones, Adam C. Soloff, Rajeev Dhupar, Lora H. Rigatti, Amanda C. LaRue, James D. Luketich

Publikováno v: Life Sciences. 282:119839

Aims Respiratory disorders are a prominent component of Gulf War Illness. Although much of the underlying mechanisms of Gulf War Illness remain undefined, chronic immune dysfunction is a consistent feature of this multi-symptomatic, multi-organ disor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713eb0238b2af8d88a05a50c06fdd46e
https://doi.org/10.1016/j.lfs.2021.119839

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Respiratory exposure to putative Gulf War toxins induces phenotypic and transcriptional alterations with effector dysfunction in alveolar macrophages

Autor: Amy A Powers, Katherine E Jones, Seth H Eisenberg, Lora H Rigatti, James D Luketich, Michael T. Lotze, Amanda C LaRue, Rajeev Dhupar, Adam C Soloff

Publikováno v: The Journal of Immunology. 206:12.20-12.20

Respiratory disorders including chronic obstructive pulmonary disease, asthma, and increased susceptibility to lung infections are a prominent component of Gulf War Illness (GWI). Although the mechanisms of GWI are unknown, chronic immune dysfunction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ab416e805dab67e7ab5521008803abc
https://doi.org/10.4049/jimmunol.206.supp.12.20

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