Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amy A. Ott"'
Autor:
Amy A. Ott, Joseph J. Topczewski
Publikováno v:
ARKIVOC, Vol 2019, Iss 1, Pp 1-17 (2019)
Externí odkaz:
https://doaj.org/article/9c647980a500440c9b85c38b79572c0e
Publikováno v:
Vaccines, Vol 12, Iss 4, p 351 (2024)
Efficacy data on two malaria vaccines, RTS,S and R21, targeting Plasmodium falciparum circumsporozoite protein (PfCSP), are encouraging. Efficacy may be improved by induction of additional antibodies to neutralizing epitopes outside of the central im
Externí odkaz:
https://doaj.org/article/98773ad8df8e4248a9d22c94a8c7f341
Autor:
Mary H. Packard, Joseph J. Topczewski, Juliana R. Alexander, Alanna M. Hildebrandt, Amy A. Ott
Publikováno v:
J Org Chem
Triazoles are privileged heterocycles for a variety of applications. The synthesis of 1H-triazoles can be accomplished by the Banert cascade from propargylic azides. Depending on the substrate and conditions, the Banert cascade can proceed by either
Autor:
Ian A. Tonks, Jason D. Goodpaster, Evan P. Beaumier, Amy A. Ott, Zachary W. Davis-Gilbert, Xuelan Wen, T. Alexander Wheeler, Joseph J. Topczewski
Publikováno v:
Chemical Science
The ring-opening oxidative amination of methylenecyclopropanes (MCPs) with diazenes catalyzed by py3TiCl2(NR) complexes is reported. This reaction selectively generates branched α-methylene imines as opposed to linear α,β-unsaturated imines, which
Autor:
Joseph J. Topczewski, Amy A. Ott
Publikováno v:
ARKIVOC, Vol 2019, Iss 1, Pp 1-17 (2019)
Allylic azides are underutilized in organic synthesis when compared to other organic azides or other allylic functionality. This is likely because allylic azides rearrange at room temperature, resulting in a potentially complex mixture of azides. Thi
Publikováno v:
Journal of the American Chemical Society. 139:7737-7740
The catalytic enantioselective preparation of densely functionalized amines is a fundamental synthetic challenge. To address this challenge, we report for the first time that the Winstein rearrangement can be enlisted as the racemization pathway in a
Publikováno v:
Org Lett
An enantioselective copper-catalyzed azide− alkyne cycloaddition (E-CuAAC) is reported by kinetic resolution. Chiral triazoles were isolated in high yield with limiting alkyne (up to 97:3 enantiomeric ratio (er)). A range of substrates were tolerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dca8373b24c9d4d058fe82bb43e0c97
https://europepmc.org/articles/PMC6631410/
https://europepmc.org/articles/PMC6631410/
Autor:
Christopher J. Cramer, Manuel A. Ortuño, Alayna M. Johnson, Victoria P. Suding, Mary H. Packard, Joseph J. Topczewski, Amy A. Ott
The spontaneous rearrangement of allylic azides is thought to be a sigmatropic reaction. Presented herein is a detailed investigation into the rearrangement of several allylic azides. A combination of experiments including equilibrium studies, kineti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd43e1d282b1b8dc75e95aa5046c2178
https://europepmc.org/articles/PMC6076873/
https://europepmc.org/articles/PMC6076873/
Autor:
Linda D. Ladd, Amy Patrick-Ott
Publikováno v:
Journal of Creativity in Mental Health. 5:73-86
When the diagnosis of a physical disability or cognitive impairment is given, the parents begin to realize that their lives will never be the same from that day forward. Whether the parent knows it or not, they have entered a period of chronic sorrow