Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Amy A. Baxter"'
Autor:
Jascinta P. Santavanond, Yu-Hsin Chiu, Rochelle Tixeira, Zonghan Liu, Jeremy K. Y. Yap, Kaiwen W. Chen, Chen-Lu Li, Yi-Ru Lu, Joan Roncero-Carol, Esteban Hoijman, Stephanie F. Rutter, Bo Shi, Gemma F. Ryan, Amy L. Hodge, Sarah Caruso, Amy A. Baxter, Dilara C. Ozkocak, Chad Johnson, Zoe I. Day, Alyce J. Mayfosh, Mark D. Hulett, Thanh K. Phan, Georgia K. Atkin-Smith, Ivan K. H. Poon
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-12 (2024)
Abstract Discovery of new small molecules that can activate distinct programmed cell death pathway is of significant interest as a research tool and for the development of novel therapeutics for pathological conditions such as cancer and infectious d
Externí odkaz:
https://doaj.org/article/62a57fe64f944d87ab3862e5bd598553
Autor:
Zoe I. Day, Alyce J. Mayfosh, Amy A. Baxter, Scott A. Williams, Joanne M. Hildebrand, Thomas F. Rau, Ivan K. H. Poon, Mark D. Hulett
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 555 (2024)
Here, we describe GS-9, a novel water-soluble fatty acid-based formulation comprising L-lysine and arachidonic acid, that we have shown to induce ferroptosis. GS-9 forms vesicle-like structures in solution and mediates lipid peroxidation, as evidence
Externí odkaz:
https://doaj.org/article/7ae74655cf7a41208939f28a5aa2a6ea
Autor:
Tien K. Nguyen, Stephanie Paone, Enoch Chan, Ivan K. H. Poon, Amy A. Baxter, Shane R. Thomas, Mark D. Hulett
Publikováno v:
Cells, Vol 11, Iss 20, p 3198 (2022)
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, and its management places a huge burden on healthcare systems through hospitalisation and treatment. Atherosclerosis is a chronic inflammatory disease of the arteria
Externí odkaz:
https://doaj.org/article/46bfd90df202454d8a17f3786326abb2
Autor:
Guneet K. Bindra, Scott A. Williams, Fung T. Lay, Amy A. Baxter, Ivan K. H. Poon, Mark D. Hulett, Thanh Kha Phan
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 264 (2022)
Defensins form an integral part of the cationic host defence peptide (HDP) family, a key component of innate immunity. Apart from their antimicrobial and immunomodulatory activities, many HDPs exert multifaceted effects on tumour cells, notably direc
Externí odkaz:
https://doaj.org/article/57fca984987f452bbb277fd4384d45b4
Autor:
Ivan K. H. Poon, Michael A. F. Parkes, Lanzhou Jiang, Georgia K. Atkin-Smith, Rochelle Tixeira, Christopher D. Gregory, Dilara C. Ozkocak, Stephanie F. Rutter, Sarah Caruso, Jascinta P. Santavanond, Stephanie Paone, Bo Shi, Amy L. Hodge, Mark D. Hulett, Jenny D. Y. Chow, Thanh Kha Phan, Amy A. Baxter
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Apoptosis is a form of programmed cell death that occurs throughout life as part of normal development as well as pathologic processes including chronic inflammation and infection. Although the death of a cell is often considered as the only biologic
Externí odkaz:
https://doaj.org/article/4b1301d0666a4cc0a4864995d3fe5b2e
Autor:
Rochelle Tixeira, Bo Shi, Michael A. F. Parkes, Amy L. Hodge, Sarah Caruso, Mark D. Hulett, Amy A. Baxter, Thanh Kha Phan, Ivan K. H. Poon
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
During the progression of necroptosis and pyroptosis, the plasma membrane will become permeabilized through the activation of mixed lineage kinase domain like pseudokinase (MLKL) or gasdermin D (GSDMD), respectively. Recently, the progression of apop
Externí odkaz:
https://doaj.org/article/0bc742297bd542a1b2d5e335c72ad039
Autor:
Amy A. Baxter
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7256 (2020)
Communication between dying cells and their environment is a critical process that promotes tissue homeostasis during normal cellular turnover, whilst during disease settings, it can contribute to inflammation through the release of intracellular fac
Externí odkaz:
https://doaj.org/article/57214cfd49fe482d9daf331b4d563256
Publikováno v:
Viruses, Vol 9, Iss 10, p 305 (2017)
Programmed cell death or apoptosis is an important component of host defense systems against viral infection. The B-cell lymphoma 2 (Bcl-2) proteins family is the main arbiter of mitochondrially mediated apoptosis, and viruses have evolved sequence a
Externí odkaz:
https://doaj.org/article/45c9fd5339c54d238893b1e3f583f246
Autor:
Josephine R. Giles, Shin Foong Ngiow, Sasikanth Manne, Amy E. Baxter, Omar Khan, Ping Wang, Ryan Staupe, Mohamed S. Abdel-Hakeem, Hua Huang, Divij Mathew, Mark M. Painter, Jennifer E. Wu, Yinghui Jane Huang, Rishi R. Goel, Patrick K. Yan, Giorgos C. Karakousis, Xiaowei Xu, Tara C. Mitchell, Alexander C. Huang, E. John Wherry
Publikováno v:
Nature Immunology. 23:1600-1613
Publikováno v:
Frontiers in Pain Research. 4
BackgroundEffective non-opioid pain management is of great clinical importance. The objective of this pilot study was to evaluate the effectiveness of multimodal mechanical stimulation therapy on low back pain.Methods11 female and 9 male patients age