Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Amy A Caudy"'
Autor:
Samantha Del Borrello, Margot Lautens, Kathleen Dolan, June H Tan, Taylor Davie, Michael R Schertzberg, Mark A Spensley, Amy A Caudy, Andrew G Fraser
Publikováno v:
eLife, Vol 8 (2019)
Parasitic helminths infect over a billion humans. To survive in the low oxygen environment of their hosts, these parasites use unusual anaerobic metabolism — this requires rhodoquinone (RQ), an electron carrier that is made by very few animal speci
Externí odkaz:
https://doaj.org/article/93eba85e4d274af2abe43dd09b991931
Autor:
Yi‐Fan Xu, Fabien Létisse, Farnaz Absalan, Wenyun Lu, Ekaterina Kuznetsova, Greg Brown, Amy A Caudy, Alexander F Yakunin, James R Broach, Joshua D Rabinowitz
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-12 (2013)
Abstract Nucleotide degradation is a universal metabolic capability. Here we combine metabolomics, genetics and biochemistry to characterize the yeast pathway. Nutrient starvation, via PKA, AMPK/SNF1, and TOR, triggers autophagic breakdown of ribosom
Externí odkaz:
https://doaj.org/article/3604c67e8fc44eb89cba3406fe3e0b45
Autor:
Zia Khan, Joshua S Bloom, Sasan Amini, Mona Singh, David H Perlman, Amy A Caudy, Leonid Kruglyak
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-12 (2012)
Abstract Understanding the genetic basis of gene regulatory variation is a key goal of evolutionary and medical genetics. Regulatory variation can act in an allele‐specific manner (cis‐acting) or it can affect both alleles of a gene (trans‐acti
Externí odkaz:
https://doaj.org/article/fb38a8f903814fb7852ab6f53283aa4c
Autor:
Matthew A Hibbs, Chad L Myers, Curtis Huttenhower, David C Hess, Kai Li, Amy A Caudy, Olga G Troyanskaya
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 3, p e1000322 (2009)
Computational approaches have promised to organize collections of functional genomics data into testable predictions of gene and protein involvement in biological processes and pathways. However, few such predictions have been experimentally validate
Externí odkaz:
https://doaj.org/article/ea002222407b409d8a20a980c83c21b5
Autor:
David C Hess, Chad L Myers, Curtis Huttenhower, Matthew A Hibbs, Alicia P Hayes, Jadine Paw, John J Clore, Rosa M Mendoza, Bryan San Luis, Corey Nislow, Guri Giaever, Michael Costanzo, Olga G Troyanskaya, Amy A Caudy
Publikováno v:
PLoS Genetics, Vol 5, Iss 3, p e1000407 (2009)
Mitochondria are central to many cellular processes including respiration, ion homeostasis, and apoptosis. Using computational predictions combined with traditional quantitative experiments, we have identified 100 proteins whose deficiency alters mit
Externí odkaz:
https://doaj.org/article/9bcdb34c562348a2a359ace7b7f8f201
Autor:
Edoardo M Airoldi, Curtis Huttenhower, David Gresham, Charles Lu, Amy A Caudy, Maitreya J Dunham, James R Broach, David Botstein, Olga G Troyanskaya
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 1, p e1000257 (2009)
Maintaining balanced growth in a changing environment is a fundamental systems-level challenge for cellular physiology, particularly in microorganisms. While the complete set of regulatory and functional pathways supporting growth and cellular prolif
Externí odkaz:
https://doaj.org/article/ad60fcee5a0945fa96811152a97b4206
Autor:
Shideh Mirhadi, Wen Zhang, Nhu-An Pham, Fereshteh Karimzadeh, Melania Pintilie, Jiefei Tong, Paul Taylor, Jonathan Krieger, Bethany Pitcher, Jenna Sykes, Leanne Wybenga-Groot, Christopher Fladd, Jing Xu, Tao Wang, Michael Cabanero, Ming Li, Jessica Weiss, Shingo Sakashita, Olga Zaslaver, Man Yu, Amy A. Caudy, Julie St-Pierre, Cynthia Hawkins, Thomas Kislinger, Geoffrey Liu, Frances A. Shepherd, Ming-Sound Tsao, Michael F. Moran
Publikováno v:
Molecular Cancer Research. 21:36-50
The ability of a patient tumor to engraft an immunodeficient mouse is the strongest known independent indicator of poor prognosis in early-stage non–small cell lung cancer (NSCLC). Analysis of primary NSCLC proteomes revealed low-level expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9826bec9a7b213aeab12d09becdd053c
https://doi.org/10.1158/1541-7786.mcr-22-0163
https://doi.org/10.1158/1541-7786.mcr-22-0163
Autor:
Michael F. Moran, Ming-Sound Tsao, Frances A. Shepherd, Geoffrey Liu, Thomas Kislinger, Cynthia Hawkins, Julie St-Pierre, Amy A. Caudy, Man Yu, Olga Zaslaver, Shingo Sakashita, Jessica Weiss, Ming Li, Michael Cabanero, Tao Wang, Jing Xu, Christopher Fladd, Leanne Wybenga-Groot, Jenna Sykes, Bethany Pitcher, Jonathan Krieger, Paul Taylor, Jiefei Tong, Melania Pintilie, Fereshteh Karimzadeh, Nhu-An Pham, Wen Zhang, Shideh Mirhadi
Statistical association of clinical and pathologic characteristics with engraftment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062dccadc19dc93706ee928786e6e9ad
https://doi.org/10.1158/1541-7786.22527308.v1
https://doi.org/10.1158/1541-7786.22527308.v1
Autor:
Michael F. Moran, Ming-Sound Tsao, Frances A. Shepherd, Geoffrey Liu, Thomas Kislinger, Cynthia Hawkins, Julie St-Pierre, Amy A. Caudy, Man Yu, Olga Zaslaver, Shingo Sakashita, Jessica Weiss, Ming Li, Michael Cabanero, Tao Wang, Jing Xu, Christopher Fladd, Leanne Wybenga-Groot, Jenna Sykes, Bethany Pitcher, Jonathan Krieger, Paul Taylor, Jiefei Tong, Melania Pintilie, Fereshteh Karimzadeh, Nhu-An Pham, Wen Zhang, Shideh Mirhadi
Clinical information and proteome quantification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b31f5e5a203139e4cb429e848c1e47
https://doi.org/10.1158/1541-7786.22527320.v1
https://doi.org/10.1158/1541-7786.22527320.v1
Autor:
Michael F. Moran, Ming-Sound Tsao, Frances A. Shepherd, Geoffrey Liu, Thomas Kislinger, Cynthia Hawkins, Julie St-Pierre, Amy A. Caudy, Man Yu, Olga Zaslaver, Shingo Sakashita, Jessica Weiss, Ming Li, Michael Cabanero, Tao Wang, Jing Xu, Christopher Fladd, Leanne Wybenga-Groot, Jenna Sykes, Bethany Pitcher, Jonathan Krieger, Paul Taylor, Jiefei Tong, Melania Pintilie, Fereshteh Karimzadeh, Nhu-An Pham, Wen Zhang, Shideh Mirhadi
S2. The associations of ACO2 expression and iron on cell proliferation and expression of proteins involved in iron regulation and ferroptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1768854e5c9885924fcb92e1aae861f6
https://doi.org/10.1158/1541-7786.22527311.v1
https://doi.org/10.1158/1541-7786.22527311.v1