Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [18F]-FDG PET-CMR

Autor: Christopher Orsborne, MBChB, Jose M. Anton-Rodrigez, PhD, Neal Sherratt, BS, Amy Watkins, BS, Maelene Lohezic, PhD, David Clark, BSc, William Lloyd, PhD, Josephine H. Naish, PhD, Peter Woolfson, MD, Anna B. Reid, PhD, Matthias Schmitt, PhD, Sivakumar Muthu, MD, Parthiban Arumugam, MD, Ana Jovanovic, MD, Christopher A. Miller, PhD

Publikováno v: JACC: Case Reports, Vol 15, Iss , Pp 101863- (2023)

Using hybridized [18F]-fluorodeoxyglucose positron emission tomography with cardiac magnetic resonance, we identify active myocardial inflammation and demonstrate its relationship with late gadolinium enhancement, in Fabry disease. We demonstrate tha

Externí odkaz: https://doaj.org/article/a3e29921f8234d87937a8d2685c20666

Increased Vulnerability to Atrial Fibrillation Is Associated With Increased Susceptibility to Alternans in Old Sheep

Autor: Charles M. Pearman, George W.P. Madders, Emma J. Radcliffe, Graeme J. Kirkwood, Michael Lawless, Amy Watkins, Charlotte E.R. Smith, Andrew W. Trafford, David A. Eisner, Katharine M. Dibb

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 23 (2018)

Background Atrial fibrillation (AF) is common in the elderly, but rare in the young; however, the changes that occur with age that promote AF are not fully understood. Action potential (AP) alternans may be involved in the initiation of AF. Using a t

Externí odkaz: https://doaj.org/article/f7e1341037234cee820cd751d17b30eb

Initial impact of COVID-19’s stay-at-home order on motor vehicle traffic and crash patterns in Connecticut: an interrupted time series analysis

Autor: Mitchell L. Doucette, Amy Watkins, Kevin Borrup, Christa Green, David Shapiro, Andrew Tucker, Garry Lapidus, Marisa E Auguste, Flavia E. Pereira

Publikováno v: Injury Prevention

IntroductionUnderstanding how the COVID-19 pandemic has impacted our health and safety is imperative. This study sought to examine the impact of COVID-19’s stay-at-home order on daily vehicle miles travelled (VMT) and MVCs in Connecticut.MethodsUsi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea73c420ee6cd3bd7fa205dc4dff61fc
https://doi.org/10.1136/injuryprev-2020-043945

Chronic vagal nerve stimulation has no effect on tachycardia‐induced heart failure progression or excitation–contraction coupling

Autor: Graeme Kirkwood, David A. Eisner, Michael Lawless, Emma J. Radcliffe, Charles M. Pearman, Amy Watkins, Andrew W. Trafford, Sophie N Saxton

Publikováno v: Physiological Reports, Vol 8, Iss 2, Pp n/a-n/a (2020)
Physiological Reports
Radcliffe, E, Pearman, C, Watkins, A, Lawless, M, Kirkwood, G, Saxton, S, Eisner, D & Trafford, A 2020, ' Chronic vagal nerve stimulation has no effect on tachycardia-induced heart failure progression or excitation-contraction coupling ', Physiological Reports, vol. 8, no. 2, e14321 . https://doi.org/10.14814/phy2.14321

Autonomic dysregulation plays a key role in the development and progression of heart failure (HF). Vagal nerve stimulation (VNS) may be a promising therapeutic approach. However, the outcomes from clinical trials evaluating VNS in HF have been mixed,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcea26ad994016fa6d4776f375c0fb80
https://doaj.org/article/94a805943b3141dc99028ded915d88c6

An improved coverage and spatial resolution-using dual injection dynamic contrast-enhanced (ICE-DICE) MRI: A novel dynamic contrast-enhanced technique for cerebral tumors

Autor: Gerard Thompson, Amy Watkins, Simon K W Lloyd, X. P. Zhu, Alan Jackson, Giovanni A Buonaccorsi, D. L. Russell, D. Gareth Evans, Ka Loh Li, John Cain, Salman Qureshi

Publikováno v: Magnetic Resonance in Medicine. 68:452-462

A new dual temporal resolution-based, high spatial resolution, pharmacokinetic parametric mapping method is described--improved coverage and spatial resolution using dual injection dynamic contrast-enhanced (ICE-DICE) MRI. In a dual-bolus dynamic con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19886b547809c5dcd4a0b9135dadfafc
https://doi.org/10.1002/mrm.23252