Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Amuri Kilonda"'
Autor:
Michael Dumbacher, Tom Van Dooren, Katrien Princen, Koen De Witte, Mélissa Farinelli, Sam Lievens, Jan Tavernier, Wim Dehaen, Stefaan Wera, Joris Winderickx, Sara Allasia, Amuri Kilonda, Stéphane Spieser, Arnaud Marchand, Patrick Chaltin, Casper C. Hoogenraad, Gerard Griffioen
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-21 (2018)
Abstract Background Neuronal Ca2+ dyshomeostasis and hyperactivity play a central role in Alzheimer’s disease pathology and progression. Amyloid-beta together with non-genetic risk-factors of Alzheimer’s disease contributes to increased Ca2+ infl
Externí odkaz:
https://doaj.org/article/d568da05c95f4ce298de12d9db169d2b
Publikováno v:
ARKIVOC, Vol 2003, Iss 4, Pp 3-21 (2002)
Externí odkaz:
https://doaj.org/article/00161562a20a4669a455da1aee2511fa
Autor:
Lei Chen, Paula Milani de Marval, Kendall Powell, Mark Johnson, Greg Falls, Brian Lawhorn, Aurélie Candi, Amuri Kilonda, Bart Vanderhoydonck, Arnaud Marchand, Matthias Versele, Georg Halder, Stephen L. Gwaltney, Adeela Kamal
Publikováno v:
Cancer Research. 83:4964-4964
Many cancers harbor mutations in the Hippo pathway that lead to constitutive activation of the transcriptional co-activators YAP/TAZ that then bind the transcription factor TEAD and drive aberrant transcription of target genes involved in cell prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff72fff7f3b3f1feb5934f47b68973aa
https://doi.org/10.1158/1538-7445.am2023-4964
https://doi.org/10.1158/1538-7445.am2023-4964
Autor:
Kalliopi Pervolaraki, Egle Katkeviciute, Dominique Lambin, Sandro Boland, Amuri Kilonda, Vincent Pericolle, Marnik Nijs, Wanda Haeck, Kristine Metzger, Hugo Klaassen, Arnaud Marchand, Patrick Chaltin, Matthias Versele, Marianne Spalinger, Michael Scharl
Publikováno v:
Cancer Research. 83:4038-4038
Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) has emerged as a promising cancer immunotherapy target. Previously, we reported on the functional role of PTPN2 in the pathogenesis of colorectal carcinoma (CRC). We demonstrated increased PTPN2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d41ea2d5071c9be156e79ebc6ee434
https://doi.org/10.1158/1538-7445.am2023-4038
https://doi.org/10.1158/1538-7445.am2023-4038
Autor:
Matthias Versele, Philippe Selhorst, Kristine Metzger, Marnik Nijs, Hugo Klaassen, Amuri Kilonda, Damien Marchand, Philippe Arzel, Dominique Lambin, Jean-Christophe Vanherck, Arnaud Marchand, Patrick Chaltin, Cyril Corbet, Olivier Feron
Publikováno v:
Cancer Research. 79:3865-3865
Inhibition of mitochondrial metabolism for treatment-resistant tumors has attracted renewed attention. Pharmacologic inhibition of mitochondrial oxidative phosphorylation (OXPHOS) is efficacious in preclinical models of chemo-resistant AML, glycolysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bd72bed9a3c49ce9e4c4d85d5c2b4e4
https://doi.org/10.1158/1538-7445.am2019-3865
https://doi.org/10.1158/1538-7445.am2019-3865
Autor:
Arnaud Marchand, Bram Sweron, Hugo Klaassen, Jan Cools, Kris Jacobs, Daphnie Pauwels, Idoya Lahortiga, Patrick Chaltin, Amuri Kilonda, Romuald Corbau
Publikováno v:
European Journal of Medicinal Chemistry. 63:713-721
FLT3 and PDGFR tyrosine kinases are important targets for therapy of different types of leukemia. Several FLT3/PDGFR inhibitors are currently under clinical investigation for combination with standard therapy for treatment of acute myeloid leukemia (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14372266e7dc0b77f9e578431a10f315
https://doi.org/10.1016/j.ejmech.2013.03.024
https://doi.org/10.1016/j.ejmech.2013.03.024
Autor:
Wim Dehaen, Dulce Maria González Mosquera, Yannarys Hernández Ortega, Amuri Kilonda, Sandra Apers, Luc Pieters
Publikováno v:
Phytochemistry letters
The anti-inflammatory effect of 4′,5-dihydroxy-6,7-methylenedioxyflavonol 3-O-α- l -rhamnopyranosyl-(1 → 2)-β- d -xylopyranoside, a constituent of the leaves of Boldoa purpurascens Cav. (Nyctaginaceae), was evaluated for its anti-inflammatory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb0ca7b702631c87ef845d03ecddf09
https://doi.org/10.1016/j.phytol.2011.04.004
https://doi.org/10.1016/j.phytol.2011.04.004
Autor:
Amuri Kilonda, Wim Dehaen, Frans Compernolle, Suzanne Toppet, Luc Pieters, Isabelle E.J.A. François, Dulce María González Mosquera, Bruno P. A. Cammue, Sandra Apers, Armando Cuellar Cuellar
Publikováno v:
Planta medica: natural products and medicinal plant research
Phytochemical analysis of the leaves of BOLDOA PURPURASCENS Cav. led to isolation of four flavone glycosides, three of which are new compounds. Their structures have been determined by mass spectrometry and by 1 D and 2 D NMR analysis, i. e., 4',5-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9860822838f60996978643eab4a01afd
https://doi.org/10.1055/s-2008-1081332
https://doi.org/10.1055/s-2008-1081332
Palladium catalyzed synthesis of Ca2+ indicators with aryl bithiophene and terthiophene fluorophores
Autor:
Noël Boens, Subhendu S. Samanta, Georges J. Hoornaert, Erik V. Van der Eycken, Amuri Kilonda, Nesibe Avcıbaşı
Publikováno v:
Tetrahedron. 62:684-690
Five new fluorescent indicators for Ca2+ were synthesized using the Stille reaction. They all consist of the tricarboxylate chelator APTRA (o-aminophenol-N,N,O-triacetic acid) linked to a (substituted) bithiophene or terthiophene fluorophore. The dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::250b6842344f848ca84928fbbbe0326b
https://doi.org/10.1016/j.tet.2005.10.002
https://doi.org/10.1016/j.tet.2005.10.002
Autor:
Babady-Bila, Tshibangu Sha Tshibey, Suzanne Toppet, Shetonde O. Mihigo, Georges J. Hoornaert, Amuri Kilonda, Frans Compernolle, Osomba Lohohola
Publikováno v:
European Journal of Organic Chemistry. 2003:123-127
A new sesquiterpene lactone, named potamopholide, was isolated along with the known triterpene lupeol from the leaves of Vernonia potamophila. The stereochemical structure of the new compound, (3R*,4S*,5E,8S*,10S*)-3,8-epoxy-3,4,13-trihydroxy-1-oxoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d75b211829f426aa0c667606839fa7fa
https://doi.org/10.1002/1099-0690(200301)2003:1<123::aid-ejoc123>3.0.co
https://doi.org/10.1002/1099-0690(200301)2003:1<123::aid-ejoc123>3.0.co