Data in support of the identification of neuronal and astrocyte proteins interacting with extracellularly applied oligomeric and fibrillar α-synuclein assemblies by mass spectrometry

Autor: Amulya Nidhi Shrivastava, Virginie Redeker, Nicolas Fritz, Laura Pieri, Leandro G. Almeida, Maria Spolidoro, Thomas Liebmann, Luc Bousset, Marianne Renner, Clément Léna, Anita Aperia, Ronald Melki, Antoine Triller

Publikováno v: Data in Brief, Vol 7, Iss , Pp 221-228 (2016)

α-Synuclein (α-syn) is the principal component of Lewy bodies, the pathophysiological hallmark of individuals affected by Parkinson disease (PD). This neuropathologic form of α-syn contributes to PD progression and propagation of α-syn assemblies

Externí odkaz: https://doaj.org/article/b26aab56cf5e428cb2bdc7e59457ca3e

Ligands binding to the cellular prion protein induce its protective proteolytic release with therapeutic potential in neurodegenerative proteinopathies

Autor: Behnam Mohammadi, Inga Zerr, Simone Hornemann, Correia A, Mohsin Shafiq, Markus Glatzel, Hermann C. Altmeppen, Jörg Tatzelt, Michaela Schweizer, Ladan Amin, David A. Harris, Julia Bär, Federica Mazzola, Matthias Schmitz, Berta Puig, Antoine Triller, Adriano Aguzzi, Karl Frontzek, Luca Varani, Da Vela S, Alexander Schwarz, Paul Saftig, Simrika Thapa, Marina Mikhaylova, Luise Linsenmeier, Emiliano Biasini, Sebastian Jung, Sabine Gilch, Dmitri I. Svergun, Markus Damme, Amulya Nidhi Shrivastava, Tania Massignan, Hermann M. Schätzl

The cellular prion protein (PrPC) is a central player in neurodegenerative diseases caused by protein misfolding, such as prion diseases or Alzheimer’s disease (AD). Expression levels of this GPI-anchored glycoprotein, especially at the neuronal ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca422690016c15fad3a8edc49ee043a1
https://doi.org/10.1101/2021.04.19.440495

Differential Membrane Binding and Seeding of Distinct $\alpha$-Synuclein Fibrillar Polymorphs

Autor: Marianne Renner, Virginie Redeker, Luc Bousset, Amulya Nidhi Shrivastava, Ronald Melki, Jimmy Savistchenko, Antoine Triller

Publikováno v: Biophysical Journal
Biophysical Journal, In press, ⟨10.1016/j.bpj.2020.01.022⟩
Biophysical journal
Biophysical Journal, Biophysical Society, In press, ⟨10.1016/j.bpj.2020.01.022⟩

The aggregation of the protein α-synuclein (α-Syn) leads to different synucleinopathies. We recently showed that structurally distinct fibrillar α-Syn polymorphs trigger either Parkinson’s disease or multiple system atrophy hallmarks in vivo. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adcfc7902197df37b0351df414b6c676
https://cea.hal.science/cea-02480815/document

Data in support of the identification of neuronal and astrocyte proteins interacting with extracellularly applied oligomeric and fibrillar α-synuclein assemblies by mass spectrometry

Autor: Virginie Redeker, Luc Bousset, Ronald Melki, Antoine Triller, Thomas Liebmann, Amulya Nidhi Shrivastava, Laura Pieri, Leandro G. Almeida, Maria Spolidoro, Anita Aperia, Marianne Renner, Clément Léna, Nicolas Fritz

Publikováno v: Data in Brief
Data in Brief, Elsevier, 2016, 7, pp.221-8. 〈10.1016/j.dib.2016.02.018〉
Data in Brief, Vol 7, Iss, Pp 221-228 (2016)
Data in Brief, Elsevier, 2016, 7, pp.221-8. ⟨10.1016/j.dib.2016.02.018⟩

α-Synuclein (α-syn) is the principal component of Lewy bodies, the pathophysiological hallmark of individuals affected by Parkinson disease (PD). This neuropathologic form of α-syn contributes to PD progression and propagation of α-syn assemblies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469b1d695a4c70a1877aeddef63d5ea1
https://doi.org/10.1016/j.dib.2016.02.018

Cell biology and dynamics of Neuronal Na+/K+-ATPase in health and diseases

Autor: Amulya Nidhi Shrivastava, Antoine Triller, Ronald Melki

Publikováno v: Neuropharmacology
Neuropharmacology, 2018, ⟨10.1016/j.neuropharm.2018.12.008⟩
Neuropharmacology, Elsevier, 2018, ⟨10.1016/j.neuropharm.2018.12.008⟩

Neuronal Na+/K+-ATPase is responsible for the maintenance of ionic gradient across plasma membrane. In doing so, in a healthy brain, Na+/K+-ATPase activity accounts for nearly half of total brain energy consumption. The α3-subunit containing Na+/K+-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79c74252fb099382d8a8994eb64942a
https://cea.hal.science/cea-02279814