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pro vyhledávání: '"Amrutha Bagivalu Lakshminarasimha"'
Autor:
Sandra Leibold, Amrutha Bagivalu Lakshminarasimha, Felix Gremse, Matthias Hammerschmidt, Maximilian Michel
Publikováno v:
PLoS ONE, Vol 17, Iss 5 (2022)
Obesity and metabolic syndrome are of increasing global concern. In order to understand the basic biology and etiology of obesity, research has turned to animals across the vertebrate spectrum including zebrafish. Here, we carefully characterize zebr
Externí odkaz:
https://doaj.org/article/1e8d124613594d159491a9d99ae36d61
Autor:
Amrutha Bagivalu Lakshminarasimha, Madhuri Puvvada, Matthias Hammerschmidt, Maximilian Michel
Publikováno v:
Journal of Endocrinology. 254:1-12
Loss of LEPR function (LOF) in mammals leads to diverse phenotypes including morbid obesity and infertility while zebrafish show relatively minor phenotypes. This however allows the study of LEPR LOF in the absence of the detrimental effects of hyper
Publikováno v:
General and Comparative Endocrinology. 336:114243
Autor:
Sandra Leibold, Amrutha Bagivalu Lakshminarasimha, Felix Gremse, Matthias Hammerschmidt, Maximilian Michel
Publikováno v:
PloS one. 17(5)
Obesity and metabolic syndrome are of increasing global concern. In order to understand the basic biology and etiology of obesity, research has turned to animals across the vertebrate spectrum including zebrafish. Here, we carefully characterize zebr
Autor:
Amrutha Bagivalu Lakshminarasimha, Maximilian Michel, Patrick S. Page-McCaw, Diana Möckel, Felix Gremse
Publikováno v:
The Journal of endocrinology. 251(1)
The leptin system plays a crucial role in the regulation of appetite and energy homeostasis in vertebrates. While the phenotype of morbid obesity due to leptin (Lep) or leptin receptor (LEPR) loss of function is well established in mammals, evidence