Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Amrutesh S, Puranik"'
Autor:
Xiangyu Zou, Soon Hyo Kwon, Kai Jiang, Christopher M. Ferguson, Amrutesh S. Puranik, Xiangyang Zhu, Lilach O. Lerman
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract To test the hypothesis that intrinsic renal scattered tubular cells (STC-like cells) contribute to repairing injured tubular epithelial cells (TEC) by releasing extracellular vesicle (EV). EV released from primary cultured pig STC-like cells
Externí odkaz:
https://doaj.org/article/b1703d65fdf346acbab51e8e5012215a
Autor:
Sabena M. Conley, John E. Shook, Xiang-Yang Zhu, Alfonso Eirin, Kyra L. Jordan, John R. Woollard, Busra Isik, LaTonya J. Hickson, Amrutesh S. Puranik, Lilach O. Lerman
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Mesenchymal stromal/stem cells (MSCs) belong to the endogenous cellular reparative system, and can be used exogenously in cell-based therapy. MSCs release extracellular vesicles (EVs), including exosomes and microvesicles, which mediate some of their
Externí odkaz:
https://doaj.org/article/6038912ef95847c8ac2184f666003f2c
Autor:
Adrian Santelli, In O. Sun, Alfonso Eirin, Abdelrhman M. Abumoawad, John R. Woollard, Amir Lerman, Stephen C. Textor, Amrutesh S. Puranik, Lilach O. Lerman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 11 (2019)
Background Hypertension may be associated with renal cellular injury. Cells in distress release extracellular vesicles (EVs), and their numbers in urine may reflect renal injury. Cellular senescence, an irreversible growth arrest in response to a nox
Externí odkaz:
https://doaj.org/article/b74fa03596b2481db9849560d6985c61
Autor:
Nattawat Klomjit, Xiang-Yang Zhu, Alfonso Eirin, Aditya S Pawar, Sabena M Conley, Amrutesh S Puranik, Christopher M Ferguson, Seo Rin Kim, Hui Tang, Kyra L Jordan, Ishran M Saadiq, Amir Lerman, Joseph P Grande, Stephen C Textor, Lilach O Lerman
Publikováno v:
Nephrol Dial Transplant
Background Renal artery stenosis (RAS) is an important cause of chronic kidney disease and secondary hypertension. In animal models, renal ischemia leads to downregulation of growth factor expression and loss of intrarenal microcirculation. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f379b009cad6ad3400af9fb8a2e9a15
https://doi.org/10.1093/ndt/gfac156
https://doi.org/10.1093/ndt/gfac156
Autor:
Alireza Khodadadi-Jamayran, Stephen C. Textor, Timothy B. Niewold, Xiangyang Zhu, Ian Taylor, Amir Lerman, Tamara Tchkonia, Lilach O. Lerman, Xiao Jun Chen, James L. Kirkland, Amrutesh S. Puranik, Seo Rin Kim, La Tonya J. Hickson, Bennett G. Childs, Kai Jiang
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Peripheral vascular diseases may induce chronic ischemia and cellular injury distal to the arterial obstruction. Cellular senescence involves proliferation arrest in response to stress, which can damage neighboring cells. Renal artery ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8cbc6c03831f61d813d9ec36ba1966
https://doi.org/10.1681/asn.2020091373
https://doi.org/10.1681/asn.2020091373
Autor:
Alfonso Eirin, Xiang-Yang Zhu, Amrutesh S Puranik, John R Woollard, Hui Tang, Surendra Dasari, Amir Lerman, Andre J van Wijnen, Lilach O Lerman
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174303 (2017)
BACKGROUND:Mesenchymal stromal/stem cell (MSC) transplantation is a promising therapy for tissue regeneration. Extracellular vesicles (EVs) released by MSCs act as their paracrine effectors by delivering proteins and genetic material to recipient cel
Externí odkaz:
https://doaj.org/article/a7651fa5d5554882a57d774f46c05b8e
Autor:
Guilherme C. de Oliveira, Tamara Tchkonia, Karthikeyani Chellappa, Karina S. Kanamori, Connor Jankowski, Katie L. Thompson, Guillermo Agorrody, Joshua D. Rabinowitz, Amrutesh S. Puranik, James L. Kirkland, Jan M. van Deursen, Kevin Dang, Gina M. Warner, Claudia C.S. Chini, Micaela A. Witte, Eduardo N. Chini, Lilian S Gomez, Starlynn Clarke, Thais Peclat, Jair Machado Espindola-Netto, Melanie R. McReynolds, Kelly A. Hogan, Marco De Cecco, Wim Van Schooten, Darren J. Baker, Paola Vidal, Bennett G. Childs, Sonu Kashyap, Mariana G. Tarragó, Joseph A. Baur, Anna L. Kirkland, John M. Sedivy
Publikováno v:
Nature metabolism
Decreased nicotinamide adenine dinucleotide (NAD+) levels have been shown to contribute to metabolic dysfunction during aging. NAD+ decline can be partially prevented by knockout of the enzyme CD38. However, it is not known how CD38 is regulated duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f293082b523d28c2c49e835f21eb18
http://europepmc.org/articles/PMC8752031
http://europepmc.org/articles/PMC8752031
Autor:
La Tonya J. Hickson, Hui Tang, James L. Kirkland, Xiangyang Zhu, Stephen C. Textor, Amrutesh S. Puranik, Tamara Tchkonia, Seo Rin Kim, Xiangyu Zou, Lilach O. Lerman, Abdelrhman Abumoawad
Publikováno v:
J Cell Physiol
Cell stress may give rise to insuperable growth arrest, which is defined as cellular senescence. Stenotic kidney (STK) ischemia and injury induced by renal artery stenosis (RAS) may be associated with cellular senescence. Mesenchymal stem cells (MSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17f9d79b0e61c3d9e418e365f8690a2
https://europepmc.org/articles/PMC7900892/
https://europepmc.org/articles/PMC7900892/
Autor:
Abdelrhman Abumoawad, Stephen C. Textor, John R. Woollard, Amir Lerman, Alfonso Eirin, Lilach O. Lerman, Adrian Santelli, Christopher M. Ferguson, Amrutesh S. Puranik, In O. Sun
Publikováno v:
Hypertension. 72:1180-1188
Hypertension, an important cause of chronic kidney disease, is characterized by peritubular capillary (PTC) loss. Circulating levels of endothelial microparticles (EMPs) reflect systemic endothelial injury. We hypothesized that systemic and urinary P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fb514ae1bf5df7184adf5cf6ea5b90
https://doi.org/10.1161/hypertensionaha.118.11766
https://doi.org/10.1161/hypertensionaha.118.11766
Autor:
Xiangyang Zhu, Amrutesh S. Puranik, Hui Tang, Kyra L. Jordan, Lilach O. Lerman, Xiangyu Zou, Kai Jiang
Publikováno v:
Stem Cells Translational Medicine
Mesenchymal stem cells (MSC) have been experimentally used for kidney repair, but modest retention limits their efficacy. Cell-surface coating allows modulating MSC homing and interaction with target cells. We coated mouse adipose tissue-derived MSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cc7e7e4a26bb16508a9939925beb8b
https://doi.org/10.1002/sctm.17-0186
https://doi.org/10.1002/sctm.17-0186