Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Amruta R. Poreddy"'
Autor:
Amolkumar S Karwa, Sungho V. Park, Amruta R. Poreddy, Raghavan Rajagopalan, Tien-Sung Lin, Yuefei Shen, Bethel Asmelash, John-Stephen Taylor
Publikováno v:
The Journal of Physical Chemistry A. 117:5454-5462
Detailed analyses of the electron spin resonance (ESR) spectra, cell viability, and DNA degradation studies are presented for the photolyzed Type I phototherapeutic agents: aromatic amines, sulfenamides, and sulfenates. The ESR studies provided evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe1818577b09daf5f6a5de5d581e2c0
https://doi.org/10.1021/jp402745m
https://doi.org/10.1021/jp402745m
Autor:
Richard B. Dorshow, Bethel Asmelash, William L. Neumann, Jeng-Jong Shieh, Kimberly R. Gaston, John N. Freskos, Richard M. Fitch, Amruta R. Poreddy, Raghavan Rajagopalan, Karen P. Galen
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:2490-2497
Novel pyrazine carboxamides bearing hydrophilic poly(ethylene glycol) (PEG) moieties were designed, synthesized, and evaluated for use as fluorescent glomerular filtration rate (GFR) tracer agents. Among these, compounds 4d and 5c that contain about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e837a5676a2e95ab4e99b82cc80665
https://doi.org/10.1016/j.bmc.2012.03.015
https://doi.org/10.1016/j.bmc.2012.03.015
Autor:
Amolkumar Karwa, Richard B. Dorshow, Tien-Sung Lin, Bethel Asmelash, Amruta R. Poreddy, Raghavan Rajagopalan
Publikováno v:
ACS Medicinal Chemistry Letters. 2:828-833
Novel type 1 phototherapeutic agents based on compounds containing S-N bonds (sulfenamides) were synthesized, assessed for free radical generation, and evaluated in vitro for cell death efficacy in four cancer cell lines (U937, HTC11, KB, and HT29).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb90a37eafd09969ca4bb516fe51518
https://doi.org/10.1021/ml2001483
https://doi.org/10.1021/ml2001483
Autor:
Kimberly R. Gaston, Amruta R. Poreddy, Jeng-Jong Shieh, William L. Neumann, Richard M. Fitch, Bethel Asmelash, Karen P. Galen, Raghavan Rajagopalan, Richard B. Dorshow, John N. Freskos
Publikováno v:
Journal of Medicinal Chemistry. 54:5048-5058
Various hydrophilic pyrazine-bis(carboxamides) derived from 3,5-diamino-pyrazine-2,5-dicarboxylic acid bearing neutral and anionic groups were prepared and evaluated for use as fluorescent glomerular filtration rate (GFR) tracer agents. Among these,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04410b5155137c0cceaf4e9dd4eabefe
https://doi.org/10.1021/jm200257k
https://doi.org/10.1021/jm200257k
Publikováno v:
Synthesis. 2010:2383-2392
A robust and scalable method was developed for the syn- thesis of N,N¢-dialkylated aminopyrazines by a reductive amination route. These new fluorescent pyrazine analogues were shown to ab- sorb and emit light at relatively long wavelengths (~50 nm)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24754eaf62ddc45a661ad36238dc1c58
https://doi.org/10.1055/s-0029-1220009
https://doi.org/10.1055/s-0029-1220009
Autor:
Jolette K. Wojdyla, Richard B. Dorshow, John N. Freskos, Karen P. Galen, Sevag Demirjian, Raghavan Rajagopalan, Richard M. Fitch, Jeng-Jong Shieh, Amruta R. Poreddy
Publikováno v:
SPIE Proceedings.
Renal function assessment is needed for the detection of acute kidney injury and chronic kidney disease. Glomerular filtration rate (GFR) is now widely accepted as the best indicator of renal function, and current clinical guidelines advocate its use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b628fdcc43d5b12247e1926fc423e4a
https://doi.org/10.1117/12.2003078
https://doi.org/10.1117/12.2003078
Autor:
Bethel Asmelash, Raghavan Rajagopalan, Amolkumar Karwa, Richard B. Dorshow, Amruta R. Poreddy, Tien-Sung Lin
The original paper was published with a C rather than an S in the table of contents and abstract graphics. The correct structure is shown below.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d8cb289828bba00018210fac5455e0
https://europepmc.org/articles/PMC4025766/
https://europepmc.org/articles/PMC4025766/
Autor:
Amolkumar Karwa, Bethel Asmelash, Raghavan Rajagopalan, Amruta R. Poreddy, Richard B. Dorshow, Tien-Sung Lin
Publikováno v:
ACS medicinal chemistry letters. 3(4)
Type 1 phototherapeutic agents based on diarylamines were assessed for free radical generation and evaluated in vitro for cell death efficacy in the U937 leukemia cancer cell line. All of the compounds were found to produce copious free radicals upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa9542978dff8c097c77298f1d63a83
https://pubmed.ncbi.nlm.nih.gov/24900465
https://pubmed.ncbi.nlm.nih.gov/24900465
Autor:
J. Micah Wilcox, Bethel Asmelash, Rana Kumar, Richard M. Fitch, Karen P. Galen, Jeng-Jong Shieh, Jolette K. Wojdyla, Amruta R. Poreddy, James G. Kostelc, John N. Freskos, Raghavan Rajagopalan, William L. Neumann, Richard B. Dorshow, Tim A. Marzan, Kimberly R. Gaston, Martin P. Debreczeny, Tasha M. Schoenstein
Publikováno v:
SPIE Proceedings.
Accurate measurement of glomerular filtration rate (GFR) at the bedside is highly desirable in order to assess renal function in real-time, which is currently an unmet clinical need. In our pursuit to develop exogenous fluorescent tracers as GFR mark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87fd694bf617e568f8adb4b6c01dd8f9
https://doi.org/10.1117/12.874917
https://doi.org/10.1117/12.874917
Publikováno v:
ChemInform. 41
N,N′-Dialkylated aminopyrazines of type (V) are easily prepared by reductive alkylation with different aldehydes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27813da7833ebdf5f3b30454a5433c44
https://doi.org/10.1002/chin.201048155
https://doi.org/10.1002/chin.201048155